Calculation Parameters
| Chain Sequence(s) |
QVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPQIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.2943 | Soluble |
| 2 | V | A | -0.4950 | Soluble |
| 3 | Q | A | -1.6061 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | Q | A | -1.8357 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | P | A | -0.9904 | Soluble |
| 8 | G | A | -1.0730 | Soluble |
| 9 | A | A | -0.9882 | Soluble |
| 11 | E | A | -1.3683 | Soluble |
| 12 | L | A | -0.5987 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | K | A | -1.8508 | Soluble |
| 15 | P | A | -1.2709 | Soluble |
| 16 | G | A | -1.1560 | Soluble |
| 17 | A | A | -0.9356 | Soluble |
| 18 | S | A | -1.1221 | Soluble |
| 19 | V | A | -1.2815 | Soluble |
| 20 | K | A | -1.9891 | Soluble |
| 21 | M | A | 0.0000 | Buried |
| 22 | S | A | -0.8094 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.4392 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0511 | Soluble |
| 27 | G | A | -0.7782 | Soluble |
| 28 | Y | A | -0.2343 | Soluble |
| 29 | T | A | -0.2246 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | -0.9305 | Soluble |
| 36 | S | A | -0.2561 | Soluble |
| 37 | Y | A | 0.2624 | Aggregation-prone |
| 38 | N | A | -0.5096 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | K | A | 0.0000 | Buried |
| 44 | Q | A | -0.6242 | Soluble |
| 45 | T | A | 0.0000 | Buried |
| 46 | P | A | -1.0296 | Soluble |
| 47 | G | A | -1.5173 | Soluble |
| 48 | R | A | -2.2334 | Soluble |
| 49 | G | A | -1.4188 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.0681 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | I | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | A | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | Y | A | -1.0176 | Soluble |
| 58 | P | A | 0.0000 | Buried |
| 59 | G | A | -1.8497 | Soluble |
| 62 | N | A | -2.5130 | Soluble |
| 63 | G | A | -2.2544 | Soluble |
| 64 | D | A | -2.4783 | Soluble |
| 65 | T | A | -1.1799 | Soluble |
| 66 | S | A | -0.9453 | Soluble |
| 67 | Y | A | -1.1184 | Soluble |
| 68 | N | A | 0.0000 | Buried |
| 69 | Q | A | -2.6859 | Soluble |
| 70 | K | A | -2.9050 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | K | A | -2.9014 | Soluble |
| 74 | G | A | -2.0177 | Soluble |
| 75 | K | A | -1.7281 | Soluble |
| 76 | A | A | 0.0000 | Buried |
| 77 | T | A | -0.9387 | Soluble |
| 78 | L | A | 0.0000 | Buried |
| 79 | T | A | -0.6397 | Soluble |
| 80 | A | A | -1.2141 | Soluble |
| 81 | D | A | -1.8404 | Soluble |
| 82 | K | A | -2.4986 | Soluble |
| 83 | S | A | -1.3799 | Soluble |
| 84 | S | A | -1.1467 | Soluble |
| 85 | S | A | -1.2450 | Soluble |
| 86 | T | A | -1.1089 | Soluble |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.4844 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | Q | A | -1.4273 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -0.9180 | Soluble |
| 93 | S | A | -0.9655 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | T | A | -1.2344 | Soluble |
| 96 | S | A | -1.3887 | Soluble |
| 97 | E | A | -1.9416 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | S | A | -0.6720 | Soluble |
| 100 | A | A | -0.2143 | Soluble |
| 101 | V | A | 0.2500 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | T | A | 0.9287 | Aggregation-prone |
| 109 | Y | A | 1.7179 | Aggregation-prone |
| 110 | Y | A | 1.5375 | Aggregation-prone |
| 111 | G | A | 0.1928 | Aggregation-prone |
| 112A | G | A | -0.0155 | Soluble |
| 112 | D | A | 0.5091 | Aggregation-prone |
| 113 | W | A | 0.9965 | Aggregation-prone |
| 114 | Y | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | N | A | -0.2168 | Soluble |
| 117 | V | A | -0.2356 | Soluble |
| 118 | W | A | -0.4435 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | A | A | -0.4319 | Soluble |
| 121 | G | A | -0.2509 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | T | A | -0.2738 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.6504 | Soluble |
| 126 | V | A | -0.8981 | Soluble |
| 127 | S | A | -0.6073 | Soluble |
| 128 | A | A | -0.6349 | Soluble |
| 129 | A | A | -0.3869 | Soluble |
| 130 | S | A | -0.5878 | Soluble |
| 131 | T | A | -0.7360 | Soluble |
| 132 | K | A | -1.1897 | Soluble |
| 133 | G | A | -1.2991 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.2939 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | 0.0000 | Buried |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.6312 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.2294 | Soluble |
| 143 | S | A | -0.4604 | Soluble |
| 144 | K | A | -0.7974 | Soluble |
| 145 | S | A | -0.7784 | Soluble |
| 146 | T | A | -0.6243 | Soluble |
| 147 | S | A | -0.8389 | Soluble |
| 148 | G | A | -0.9977 | Soluble |
| 149 | G | A | -0.9413 | Soluble |
| 150 | T | A | -0.6439 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.3055 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.9595 | Soluble |
| 164 | P | A | -0.9616 | Soluble |
| 165 | V | A | -0.7447 | Soluble |
| 166 | T | A | -0.6604 | Soluble |
| 167 | V | A | 0.0000 | Buried |
| 168 | S | A | -0.5670 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.8460 | Soluble |
| 171 | S | A | -0.5887 | Soluble |
| 172 | G | A | -0.6410 | Soluble |
| 173 | A | A | -0.2614 | Soluble |
| 174 | L | A | -0.0120 | Soluble |
| 175 | T | A | -0.1654 | Soluble |
| 176 | S | A | -0.1569 | Soluble |
| 177 | G | A | -0.1870 | Soluble |
| 178 | V | A | 0.1966 | Aggregation-prone |
| 179 | H | A | -0.3320 | Soluble |
| 180 | T | A | -0.1727 | Soluble |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.5009 | Soluble |
| 183 | A | A | 0.2719 | Aggregation-prone |
| 184 | V | A | 0.6718 | Aggregation-prone |
| 185 | L | A | 1.5324 | Aggregation-prone |
| 186 | Q | A | 0.4190 | Aggregation-prone |
| 187 | S | A | -0.0407 | Soluble |
| 188 | S | A | -0.2154 | Soluble |
| 189 | G | A | 0.0102 | Aggregation-prone |
| 190 | L | A | 0.1711 | Aggregation-prone |
| 191 | Y | A | 0.5016 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.3586 | Aggregation-prone |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1152 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5608 | Soluble |
| 201 | S | A | -0.7246 | Soluble |
| 202 | S | A | -0.5496 | Soluble |
| 203 | S | A | -0.6049 | Soluble |
| 204 | L | A | -0.7506 | Soluble |
| 205 | G | A | -1.0239 | Soluble |
| 206 | T | A | -0.7196 | Soluble |
| 207 | Q | A | -1.0273 | Soluble |
| 208 | T | A | -1.1738 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.3409 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.6362 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.8878 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.8616 | Soluble |
| 217 | P | A | -1.7752 | Soluble |
| 218 | S | A | -1.8047 | Soluble |
| 219 | N | A | -2.4952 | Soluble |
| 220 | T | A | -2.1726 | Soluble |
| 221 | K | A | -2.6059 | Soluble |
| 222 | V | A | -1.5631 | Soluble |
| 223 | D | A | -2.5692 | Soluble |
| 224 | K | A | -2.0824 | Soluble |
| 225 | K | A | -2.6900 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.4044 | Soluble |
| 228 | P | A | -1.4446 | Soluble |
| 1 | Q | B | -1.0179 | Soluble |
| 2 | I | B | 0.1648 | Aggregation-prone |
| 3 | V | B | 1.1308 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | S | B | -0.6071 | Soluble |
| 6 | Q | B | -0.7098 | Soluble |
| 7 | S | B | -0.5345 | Soluble |
| 8 | P | B | -0.0140 | Soluble |
| 9 | A | B | 0.1471 | Aggregation-prone |
| 10 | I | B | 0.6448 | Aggregation-prone |
| 11 | L | B | -0.1222 | Soluble |
| 12 | S | B | -0.9955 | Soluble |
| 13 | A | B | 0.0000 | Buried |
| 14 | S | B | -2.2977 | Soluble |
| 15 | P | B | -2.5663 | Soluble |
| 16 | G | B | -2.7304 | Soluble |
| 17 | E | B | -3.5189 | Soluble |
| 18 | K | B | -3.1951 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.6337 | Soluble |
| 21 | M | B | 0.0000 | Buried |
| 22 | T | B | -0.6689 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -1.8135 | Soluble |
| 25 | A | B | -0.6096 | Soluble |
| 26 | S | B | -0.3080 | Soluble |
| 27 | S | B | -0.4316 | Soluble |
| 28 | S | B | -0.6398 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 37 | S | B | -0.1980 | Soluble |
| 38 | Y | B | 0.1536 | Aggregation-prone |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | F | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.5116 | Soluble |
| 46 | P | B | -1.0411 | Soluble |
| 47 | G | B | -0.7391 | Soluble |
| 48 | S | B | -0.8072 | Soluble |
| 49 | S | B | -0.6614 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.7342 | Soluble |
| 52 | P | B | -0.7609 | Soluble |
| 53 | W | B | -0.4089 | Soluble |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.2873 | Aggregation-prone |
| 56 | A | B | 0.1064 | Aggregation-prone |
| 57 | T | B | -0.2254 | Soluble |
| 65 | S | B | -0.4426 | Soluble |
| 66 | N | B | -0.4501 | Soluble |
| 67 | L | B | 0.4273 | Aggregation-prone |
| 68 | A | B | 0.0000 | Buried |
| 69 | S | B | -0.3973 | Soluble |
| 70 | G | B | -0.2749 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | 0.6671 | Aggregation-prone |
| 74 | V | B | 1.4165 | Aggregation-prone |
| 75 | R | B | -0.2874 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0012 | Soluble |
| 78 | G | B | -0.4237 | Soluble |
| 79 | S | B | -0.6354 | Soluble |
| 80 | G | B | -0.8587 | Soluble |
| 83 | S | B | -0.7400 | Soluble |
| 84 | G | B | -0.6897 | Soluble |
| 85 | T | B | -0.9519 | Soluble |
| 86 | S | B | -1.1636 | Soluble |
| 87 | Y | B | 0.0000 | Buried |
| 88 | S | B | -0.6342 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.7611 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.0114 | Soluble |
| 93 | R | B | -3.1920 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.6305 | Soluble |
| 96 | A | B | -2.6369 | Soluble |
| 97 | E | B | -2.6853 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | A | B | -1.9475 | Soluble |
| 100 | A | B | -1.2576 | Soluble |
| 101 | T | B | 0.0000 | Buried |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | -0.3794 | Soluble |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | W | B | -0.0812 | Soluble |
| 108 | T | B | -0.2655 | Soluble |
| 109 | S | B | -0.9438 | Soluble |
| 114 | N | B | -1.5224 | Soluble |
| 115 | P | B | -1.4694 | Soluble |
| 116 | P | B | 0.0000 | Buried |
| 117 | T | B | -0.1540 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.9001 | Soluble |
| 121 | G | B | -0.4791 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.1539 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | -1.3945 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -2.1168 | Soluble |
| 128 | R | B | -1.2053 | Soluble |
| 129 | T | B | 0.1497 | Aggregation-prone |
| 130 | V | B | 1.2351 | Aggregation-prone |
| 131 | A | B | 0.3273 | Aggregation-prone |
| 132 | A | B | 0.0233 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2423 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0169 | Aggregation-prone |
| 137 | I | B | -0.0007 | Soluble |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4094 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.8602 | Soluble |
| 142 | D | B | -2.9685 | Soluble |
| 143 | E | B | -3.0255 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.3484 | Soluble |
| 146 | K | B | -2.7107 | Soluble |
| 147 | S | B | -1.7381 | Soluble |
| 148 | G | B | -1.2377 | Soluble |
| 149 | T | B | -0.8675 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | -0.3991 | Soluble |
| 158 | N | B | -0.9162 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | -0.8812 | Soluble |
| 161 | P | B | -1.5823 | Soluble |
| 162 | R | B | -3.1751 | Soluble |
| 163 | E | B | -3.2744 | Soluble |
| 164 | A | B | -2.3582 | Soluble |
| 165 | K | B | -2.3566 | Soluble |
| 166 | V | B | -1.1110 | Soluble |
| 167 | Q | B | -0.5540 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.4169 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.4562 | Soluble |
| 172 | N | B | -1.3025 | Soluble |
| 173 | A | B | -0.1022 | Soluble |
| 174 | L | B | 0.7829 | Aggregation-prone |
| 175 | Q | B | -0.1420 | Soluble |
| 176 | S | B | -0.4406 | Soluble |
| 177 | G | B | -0.8480 | Soluble |
| 178 | N | B | -0.7259 | Soluble |
| 179 | S | B | -1.0062 | Soluble |
| 180 | Q | B | -1.1203 | Soluble |
| 181 | E | B | -1.8001 | Soluble |
| 182 | S | B | -0.8728 | Soluble |
| 183 | V | B | -0.6908 | Soluble |
| 184 | T | B | -1.0736 | Soluble |
| 185 | E | B | -2.1873 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.1139 | Soluble |
| 188 | S | B | -2.4142 | Soluble |
| 189 | K | B | -2.7119 | Soluble |
| 190 | D | B | -2.0209 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | 0.0000 | Buried |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.2243 | Soluble |
| 201 | L | B | -0.3657 | Soluble |
| 202 | S | B | -1.1884 | Soluble |
| 203 | K | B | -2.1364 | Soluble |
| 204 | A | B | -1.9619 | Soluble |
| 205 | D | B | -2.5206 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.4455 | Soluble |
| 208 | K | B | -3.5328 | Soluble |
| 209 | H | B | -2.9156 | Soluble |
| 210 | K | B | -3.0520 | Soluble |
| 211 | V | B | -1.1716 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7562 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1825 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.4512 | Soluble |
| 220 | G | B | -0.2339 | Soluble |
| 221 | L | B | -0.2066 | Soluble |
| 222 | S | B | -0.4454 | Soluble |
| 223 | S | B | -0.4516 | Soluble |
| 224 | P | B | -0.5556 | Soluble |
| 225 | V | B | -0.0488 | Soluble |
| 226 | T | B | -0.5692 | Soluble |
| 227 | K | B | -0.9178 | Soluble |
| 228 | S | B | -0.6686 | Soluble |
| 229 | F | B | -0.8793 | Soluble |
| 230 | N | B | -1.8424 | Soluble |
| 231 | R | B | -2.3903 | Soluble |
| 232 | G | B | -1.9377 | Soluble |
| 233 | E | B | -2.2443 | Soluble |
| 234 | C | B | -0.5674 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7328 | 2.2669 | CSV PDB |
| 4.5 | -0.7688 | 2.2522 | CSV PDB |
| 5.0 | -0.8112 | 2.2402 | CSV PDB |
| 5.5 | -0.8492 | 2.228 | CSV PDB |
| 6.0 | -0.8702 | 2.2158 | CSV PDB |
| 6.5 | -0.865 | 2.2037 | CSV PDB |
| 7.0 | -0.8341 | 2.1916 | CSV PDB |
| 7.5 | -0.7863 | 2.1798 | CSV PDB |
| 8.0 | -0.7298 | 2.1688 | CSV PDB |
| 8.5 | -0.6684 | 2.1585 | CSV PDB |
| 9.0 | -0.6031 | 2.1458 | CSV PDB |