Calculation Parameters
| Chain Sequence(s) |
QVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCQIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.1532 | Soluble |
| 2 | V | A | -0.3405 | Soluble |
| 3 | Q | A | -1.1182 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | Q | A | -1.4134 | Soluble |
| 6 | Q | A | -0.9299 | Soluble |
| 7 | P | A | -0.7493 | Soluble |
| 8 | G | A | -0.7080 | Soluble |
| 9 | A | A | -0.2523 | Soluble |
| 11 | E | A | -0.3739 | Soluble |
| 12 | L | A | 0.3050 | Aggregation-prone |
| 13 | V | A | 0.0000 | Buried |
| 14 | K | A | -1.6960 | Soluble |
| 15 | P | A | -1.2170 | Soluble |
| 16 | G | A | -1.1129 | Soluble |
| 17 | A | A | -0.9295 | Soluble |
| 18 | S | A | -1.0754 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.7994 | Soluble |
| 21 | M | A | 0.0000 | Buried |
| 22 | S | A | -0.7304 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.1683 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.7434 | Soluble |
| 27 | G | A | -0.5754 | Soluble |
| 28 | Y | A | -0.0976 | Soluble |
| 29 | T | A | -0.1345 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | -0.6873 | Soluble |
| 36 | S | A | -0.0810 | Soluble |
| 37 | Y | A | 0.4668 | Aggregation-prone |
| 38 | N | A | -0.0565 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | K | A | 0.0000 | Buried |
| 44 | Q | A | -0.6061 | Soluble |
| 45 | T | A | 0.0000 | Buried |
| 46 | P | A | -1.0538 | Soluble |
| 47 | G | A | -1.5083 | Soluble |
| 48 | R | A | -2.2031 | Soluble |
| 49 | G | A | -1.3729 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.8552 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | I | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | A | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | Y | A | -0.6384 | Soluble |
| 58 | P | A | 0.0000 | Buried |
| 59 | G | A | -1.3624 | Soluble |
| 62 | N | A | -2.0794 | Soluble |
| 63 | G | A | -1.9858 | Soluble |
| 64 | D | A | -2.2602 | Soluble |
| 65 | T | A | -1.1097 | Soluble |
| 66 | S | A | -0.9878 | Soluble |
| 67 | Y | A | -1.2551 | Soluble |
| 68 | N | A | 0.0000 | Buried |
| 69 | Q | A | -2.7442 | Soluble |
| 70 | K | A | -2.7664 | Soluble |
| 71 | F | A | -2.0807 | Soluble |
| 72 | K | A | -2.7579 | Soluble |
| 74 | G | A | -1.8627 | Soluble |
| 75 | K | A | -1.5106 | Soluble |
| 76 | A | A | 0.0000 | Buried |
| 77 | T | A | -0.8258 | Soluble |
| 78 | L | A | 0.0000 | Buried |
| 79 | T | A | -0.6870 | Soluble |
| 80 | A | A | -0.8771 | Soluble |
| 81 | D | A | -1.5295 | Soluble |
| 82 | K | A | -2.3085 | Soluble |
| 83 | S | A | -1.2708 | Soluble |
| 84 | S | A | -0.9652 | Soluble |
| 85 | S | A | -1.1076 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.4645 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | Q | A | -1.1685 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -0.8342 | Soluble |
| 93 | S | A | -0.7979 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | T | A | -1.2620 | Soluble |
| 96 | S | A | -1.4041 | Soluble |
| 97 | E | A | -1.9609 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | S | A | -0.6296 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.1278 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | T | A | 1.0401 | Aggregation-prone |
| 109 | Y | A | 1.9441 | Aggregation-prone |
| 110 | Y | A | 1.6145 | Aggregation-prone |
| 111 | G | A | 0.2552 | Aggregation-prone |
| 112A | G | A | 0.3300 | Aggregation-prone |
| 112 | D | A | 0.0000 | Buried |
| 113 | W | A | 1.3732 | Aggregation-prone |
| 114 | Y | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | N | A | -0.1041 | Soluble |
| 117 | V | A | -0.2562 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | A | A | -0.3975 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | T | A | -0.0353 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.5144 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.5338 | Soluble |
| 128 | A | A | -0.5547 | Soluble |
| 129 | A | A | -0.4081 | Soluble |
| 130 | S | A | -0.6438 | Soluble |
| 131 | T | A | -0.9119 | Soluble |
| 132 | K | A | -1.0429 | Soluble |
| 133 | G | A | -1.2707 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3325 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -0.7460 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | 0.0000 | Buried |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.2899 | Soluble |
| 143 | S | A | -0.3186 | Soluble |
| 144 | K | A | -0.4953 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.5098 | Soluble |
| 147 | S | A | -0.5921 | Soluble |
| 148 | G | A | -0.7874 | Soluble |
| 149 | G | A | -0.8713 | Soluble |
| 150 | T | A | -0.6323 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.3017 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | -1.1669 | Soluble |
| 163 | E | A | -1.6054 | Soluble |
| 164 | P | A | -1.3687 | Soluble |
| 165 | V | A | -1.0610 | Soluble |
| 166 | T | A | -0.6973 | Soluble |
| 167 | V | A | -0.2461 | Soluble |
| 168 | S | A | -0.2904 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.6503 | Soluble |
| 171 | S | A | -0.5601 | Soluble |
| 172 | G | A | -0.4716 | Soluble |
| 173 | A | A | -0.2031 | Soluble |
| 174 | L | A | -0.0293 | Soluble |
| 175 | T | A | -0.1897 | Soluble |
| 176 | S | A | -0.2009 | Soluble |
| 177 | G | A | -0.2240 | Soluble |
| 178 | V | A | 0.1409 | Aggregation-prone |
| 179 | H | A | -0.2415 | Soluble |
| 180 | T | A | 0.0568 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.4634 | Soluble |
| 183 | A | A | 0.0335 | Aggregation-prone |
| 184 | V | A | 0.2107 | Aggregation-prone |
| 185 | L | A | 0.7485 | Aggregation-prone |
| 186 | Q | A | 0.1609 | Aggregation-prone |
| 187 | S | A | -0.1234 | Soluble |
| 188 | S | A | -0.2203 | Soluble |
| 189 | G | A | 0.0217 | Aggregation-prone |
| 190 | L | A | -0.1719 | Soluble |
| 191 | Y | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1376 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5431 | Soluble |
| 201 | S | A | -0.6268 | Soluble |
| 202 | S | A | -0.6562 | Soluble |
| 203 | S | A | -0.6889 | Soluble |
| 204 | L | A | 0.0000 | Buried |
| 205 | G | A | -1.1014 | Soluble |
| 206 | T | A | -0.7649 | Soluble |
| 207 | Q | A | -1.0087 | Soluble |
| 208 | T | A | -1.0433 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -0.7377 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | 0.0000 | Buried |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.9045 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7667 | Soluble |
| 217 | P | A | -1.8163 | Soluble |
| 218 | S | A | -1.8145 | Soluble |
| 219 | N | A | -2.5928 | Soluble |
| 220 | T | A | -2.0981 | Soluble |
| 221 | K | A | -2.5365 | Soluble |
| 222 | V | A | -1.2763 | Soluble |
| 223 | D | A | -1.9353 | Soluble |
| 224 | K | A | -1.4170 | Soluble |
| 225 | K | A | -1.9597 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -1.3236 | Soluble |
| 228 | P | A | -1.1258 | Soluble |
| 229 | K | A | -1.9294 | Soluble |
| 230 | S | A | -1.0919 | Soluble |
| 231 | C | A | -0.3502 | Soluble |
| 1 | Q | B | -1.1807 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.9834 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | S | B | -0.6981 | Soluble |
| 6 | Q | B | -0.6976 | Soluble |
| 7 | S | B | -0.6730 | Soluble |
| 8 | P | B | -0.1677 | Soluble |
| 9 | A | B | -0.1571 | Soluble |
| 10 | I | B | 0.1748 | Aggregation-prone |
| 11 | L | B | -0.1477 | Soluble |
| 12 | S | B | -0.9267 | Soluble |
| 13 | A | B | 0.0000 | Buried |
| 14 | S | B | -2.1080 | Soluble |
| 15 | P | B | -2.3972 | Soluble |
| 16 | G | B | -2.5229 | Soluble |
| 17 | E | B | -3.2606 | Soluble |
| 18 | K | B | -3.1793 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.5911 | Soluble |
| 21 | M | B | 0.0000 | Buried |
| 22 | T | B | -0.7063 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -1.8999 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -0.3810 | Soluble |
| 27 | S | B | -0.5107 | Soluble |
| 28 | S | B | -0.7041 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 37 | S | B | -0.1656 | Soluble |
| 38 | Y | B | 0.1923 | Aggregation-prone |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | F | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.1663 | Soluble |
| 45 | K | B | -1.5971 | Soluble |
| 46 | P | B | -1.1669 | Soluble |
| 47 | G | B | -0.8181 | Soluble |
| 48 | S | B | -0.8862 | Soluble |
| 49 | S | B | -0.6838 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.5301 | Soluble |
| 52 | P | B | -0.7232 | Soluble |
| 53 | W | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.0922 | Aggregation-prone |
| 56 | A | B | 0.0000 | Buried |
| 57 | T | B | -0.2900 | Soluble |
| 65 | S | B | -0.4637 | Soluble |
| 66 | N | B | -0.6918 | Soluble |
| 67 | L | B | 0.1449 | Aggregation-prone |
| 68 | A | B | 0.0000 | Buried |
| 69 | S | B | -0.4970 | Soluble |
| 70 | G | B | -0.2741 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | 0.5779 | Aggregation-prone |
| 74 | V | B | 1.5297 | Aggregation-prone |
| 75 | R | B | -0.3293 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0239 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -0.5387 | Soluble |
| 80 | G | B | -0.7167 | Soluble |
| 83 | S | B | -0.6873 | Soluble |
| 84 | G | B | -0.7051 | Soluble |
| 85 | T | B | -0.9889 | Soluble |
| 86 | S | B | -1.1189 | Soluble |
| 87 | Y | B | 0.0000 | Buried |
| 88 | S | B | -0.6026 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8128 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.0933 | Soluble |
| 93 | R | B | -3.5904 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.8508 | Soluble |
| 96 | A | B | -2.2554 | Soluble |
| 97 | E | B | -2.4124 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | A | B | -1.2110 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.7474 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | W | B | -0.1096 | Soluble |
| 108 | T | B | -0.3797 | Soluble |
| 109 | S | B | -1.0555 | Soluble |
| 114 | N | B | -1.7243 | Soluble |
| 115 | P | B | 0.0000 | Buried |
| 116 | P | B | 0.0000 | Buried |
| 117 | T | B | -0.1916 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.9127 | Soluble |
| 121 | G | B | -0.6092 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.0630 | Soluble |
| 124 | L | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.9728 | Soluble |
| 128 | R | B | -1.0314 | Soluble |
| 129 | T | B | 0.1877 | Aggregation-prone |
| 130 | V | B | 1.0732 | Aggregation-prone |
| 131 | A | B | 0.5466 | Aggregation-prone |
| 132 | A | B | 0.1240 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2677 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | 0.0000 | Buried |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | 0.0000 | Buried |
| 142 | D | B | -1.6438 | Soluble |
| 143 | E | B | -1.7970 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.7320 | Soluble |
| 146 | K | B | -2.3936 | Soluble |
| 147 | S | B | -1.4955 | Soluble |
| 148 | G | B | -1.3212 | Soluble |
| 149 | T | B | -1.1333 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.6307 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.0084 | Soluble |
| 162 | R | B | -1.7512 | Soluble |
| 163 | E | B | -2.0099 | Soluble |
| 164 | A | B | -1.7043 | Soluble |
| 165 | K | B | -2.0296 | Soluble |
| 166 | V | B | 0.0000 | Buried |
| 167 | Q | B | -0.6321 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.6862 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.7796 | Soluble |
| 172 | N | B | -1.5539 | Soluble |
| 173 | A | B | -0.4470 | Soluble |
| 174 | L | B | 0.4427 | Aggregation-prone |
| 175 | Q | B | -0.2690 | Soluble |
| 176 | S | B | -0.5500 | Soluble |
| 177 | G | B | -0.9491 | Soluble |
| 178 | N | B | -0.8891 | Soluble |
| 179 | S | B | -1.0796 | Soluble |
| 180 | Q | B | -1.2429 | Soluble |
| 181 | E | B | -1.5231 | Soluble |
| 182 | S | B | -0.5726 | Soluble |
| 183 | V | B | -0.1905 | Soluble |
| 184 | T | B | -0.8123 | Soluble |
| 185 | E | B | -2.0984 | Soluble |
| 186 | Q | B | -1.8549 | Soluble |
| 187 | D | B | -2.1323 | Soluble |
| 188 | S | B | -2.0841 | Soluble |
| 189 | K | B | -2.3481 | Soluble |
| 190 | D | B | -1.8850 | Soluble |
| 191 | S | B | -2.0128 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | -1.0339 | Soluble |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.5604 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4906 | Soluble |
| 201 | L | B | -0.7518 | Soluble |
| 202 | S | B | -1.3410 | Soluble |
| 203 | K | B | -2.2267 | Soluble |
| 204 | A | B | -2.0442 | Soluble |
| 205 | D | B | -2.7660 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.2472 | Soluble |
| 208 | K | B | -3.4763 | Soluble |
| 209 | H | B | -2.8695 | Soluble |
| 210 | K | B | -2.6831 | Soluble |
| 211 | V | B | -1.2316 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.5445 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.6551 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -0.9642 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.1892 | Soluble |
| 220 | G | B | -0.2018 | Soluble |
| 221 | L | B | -0.0872 | Soluble |
| 222 | S | B | -0.3913 | Soluble |
| 223 | S | B | -0.3610 | Soluble |
| 224 | P | B | -0.4616 | Soluble |
| 225 | V | B | 0.1833 | Aggregation-prone |
| 226 | T | B | -0.2290 | Soluble |
| 227 | K | B | -0.3673 | Soluble |
| 228 | S | B | -0.4338 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.4886 | Soluble |
| 231 | R | B | -1.8844 | Soluble |
| 232 | G | B | -1.4602 | Soluble |
| 233 | E | B | -1.5573 | Soluble |
| 234 | C | B | -0.3828 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6704 | 2.8492 | CSV PDB |
| 4.5 | -0.7001 | 2.8492 | CSV PDB |
| 5.0 | -0.734 | 2.8492 | CSV PDB |
| 5.5 | -0.7631 | 2.8492 | CSV PDB |
| 6.0 | -0.7765 | 2.8492 | CSV PDB |
| 6.5 | -0.7665 | 2.8492 | CSV PDB |
| 7.0 | -0.7339 | 2.8492 | CSV PDB |
| 7.5 | -0.6868 | 2.8491 | CSV PDB |
| 8.0 | -0.6321 | 2.8488 | CSV PDB |
| 8.5 | -0.5727 | 2.848 | CSV PDB |
| 9.0 | -0.5098 | 2.8452 | CSV PDB |