Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.2291 | Soluble |
| 2 | V | A | -0.6068 | Soluble |
| 3 | Q | A | -0.9695 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.2961 | Aggregation-prone |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.5333 | Soluble |
| 8 | G | A | -0.5442 | Soluble |
| 9 | A | A | 0.1046 | Aggregation-prone |
| 11 | E | A | -0.3302 | Soluble |
| 12 | V | A | 0.9932 | Aggregation-prone |
| 13 | K | A | -0.7954 | Soluble |
| 14 | K | A | -1.9763 | Soluble |
| 15 | P | A | -2.3891 | Soluble |
| 16 | G | A | -2.2665 | Soluble |
| 17 | A | A | -1.7872 | Soluble |
| 18 | S | A | -1.9058 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.0078 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.4118 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -0.5029 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.5512 | Soluble |
| 27 | G | A | -0.7013 | Soluble |
| 28 | Y | A | -0.3082 | Soluble |
| 29 | P | A | -0.1959 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.2056 | Aggregation-prone |
| 36 | S | A | 0.3637 | Aggregation-prone |
| 37 | Y | A | 0.4726 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.4196 | Soluble |
| 45 | A | A | -0.8263 | Soluble |
| 46 | P | A | -0.7001 | Soluble |
| 47 | G | A | -1.2097 | Soluble |
| 48 | Q | A | -1.7202 | Soluble |
| 49 | G | A | -1.0749 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.7758 | Soluble |
| 52 | W | A | -0.2617 | Soluble |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.3245 | Aggregation-prone |
| 62 | N | A | -1.0060 | Soluble |
| 63 | G | A | -1.3835 | Soluble |
| 64 | N | A | -1.5595 | Soluble |
| 65 | T | A | -1.1810 | Soluble |
| 66 | N | A | -1.1607 | Soluble |
| 67 | Y | A | -1.0165 | Soluble |
| 68 | A | A | -1.4135 | Soluble |
| 69 | Q | A | -2.4298 | Soluble |
| 70 | K | A | -2.6545 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.2621 | Soluble |
| 74 | G | A | -1.7783 | Soluble |
| 75 | R | A | -1.7956 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.7222 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.3796 | Soluble |
| 80 | T | A | -0.6464 | Soluble |
| 81 | D | A | -0.7689 | Soluble |
| 82 | T | A | -0.3888 | Soluble |
| 83 | S | A | -0.4787 | Soluble |
| 84 | T | A | -0.5218 | Soluble |
| 85 | T | A | -0.5707 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.3320 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.2161 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -2.4264 | Soluble |
| 93 | R | A | -3.0913 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.4864 | Soluble |
| 96 | S | A | -2.2431 | Soluble |
| 97 | D | A | -2.4480 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.6343 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.5975 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.2740 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 0.8570 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.2734 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.4683 | Aggregation-prone |
| 111C | F | A | 1.5711 | Aggregation-prone |
| 112D | G | A | -0.3688 | Soluble |
| 112C | E | A | -1.3394 | Soluble |
| 112B | S | A | -0.6526 | Soluble |
| 112A | L | A | 0.5346 | Aggregation-prone |
| 112 | I | A | 2.1626 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.6734 | Soluble |
| 117 | N | A | -0.7248 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.1767 | Soluble |
| 121 | G | A | -0.3743 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.8480 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.2117 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0596 | Soluble |
| 128 | S | A | -1.0583 | Soluble |
| 129 | A | A | -0.6057 | Soluble |
| 130 | S | A | -0.6309 | Soluble |
| 131 | T | A | -0.6203 | Soluble |
| 132 | K | A | -1.0493 | Soluble |
| 133 | G | A | -1.2277 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.1796 | Soluble |
| 136 | V | A | -0.0327 | Soluble |
| 137 | F | A | -0.4858 | Soluble |
| 138 | P | A | -0.9219 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.1155 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.9129 | Soluble |
| 143 | S | A | -0.4132 | Soluble |
| 144 | G | A | -0.8451 | Soluble |
| 145 | G | A | -0.8402 | Soluble |
| 146 | T | A | -0.5794 | Soluble |
| 147 | A | A | -0.3540 | Soluble |
| 148 | A | A | 0.0000 | Buried |
| 149 | L | A | 0.0000 | Buried |
| 150 | G | A | 0.0000 | Buried |
| 151 | C | A | 0.0000 | Buried |
| 152 | L | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | K | A | 0.0000 | Buried |
| 155 | D | A | -0.2352 | Soluble |
| 156 | Y | A | 0.0000 | Buried |
| 157 | F | A | 0.0000 | Buried |
| 158 | P | A | -0.3588 | Soluble |
| 159 | E | A | -0.8033 | Soluble |
| 160 | P | A | -0.9810 | Soluble |
| 161 | V | A | -0.7669 | Soluble |
| 162 | T | A | -0.6547 | Soluble |
| 163 | V | A | -0.2896 | Soluble |
| 164 | S | A | -0.3556 | Soluble |
| 165 | W | A | 0.0000 | Buried |
| 166 | N | A | -0.6513 | Soluble |
| 167 | S | A | -0.6008 | Soluble |
| 168 | G | A | -0.5782 | Soluble |
| 169 | A | A | -0.2476 | Soluble |
| 170 | L | A | -0.0364 | Soluble |
| 171 | T | A | -0.1794 | Soluble |
| 172 | S | A | -0.3651 | Soluble |
| 173 | G | A | -0.2369 | Soluble |
| 174 | V | A | 0.1471 | Aggregation-prone |
| 175 | H | A | 0.0000 | Buried |
| 176 | T | A | 0.0613 | Aggregation-prone |
| 177 | F | A | 0.0000 | Buried |
| 178 | P | A | -0.2832 | Soluble |
| 179 | A | A | 0.3005 | Aggregation-prone |
| 180 | V | A | 0.6906 | Aggregation-prone |
| 181 | L | A | 1.2715 | Aggregation-prone |
| 182 | Q | A | 0.2974 | Aggregation-prone |
| 183 | S | A | -0.0327 | Soluble |
| 184 | S | A | -0.1855 | Soluble |
| 185 | G | A | 0.0424 | Aggregation-prone |
| 186 | L | A | 0.1516 | Aggregation-prone |
| 187 | Y | A | 0.4895 | Aggregation-prone |
| 188 | S | A | 0.0000 | Buried |
| 189 | L | A | 0.3883 | Aggregation-prone |
| 190 | S | A | 0.0000 | Buried |
| 191 | S | A | 0.0000 | Buried |
| 192 | V | A | 0.0000 | Buried |
| 193 | V | A | 0.0000 | Buried |
| 194 | T | A | -0.2014 | Soluble |
| 195 | V | A | 0.0000 | Buried |
| 196 | P | A | -0.6547 | Soluble |
| 197 | S | A | -0.7732 | Soluble |
| 198 | S | A | -0.6907 | Soluble |
| 199 | S | A | -0.7249 | Soluble |
| 200 | L | A | -0.9726 | Soluble |
| 201 | G | A | -1.1388 | Soluble |
| 202 | T | A | -1.0631 | Soluble |
| 203 | Q | A | -1.6184 | Soluble |
| 204 | T | A | -1.2748 | Soluble |
| 205 | Y | A | 0.0000 | Buried |
| 206 | I | A | -1.0467 | Soluble |
| 207 | C | A | 0.0000 | Buried |
| 208 | N | A | -1.1120 | Soluble |
| 209 | V | A | 0.0000 | Buried |
| 210 | N | A | -1.8702 | Soluble |
| 211 | H | A | 0.0000 | Buried |
| 212 | K | A | -2.7256 | Soluble |
| 213 | P | A | -1.6124 | Soluble |
| 214 | S | A | -1.7419 | Soluble |
| 215 | N | A | -2.5610 | Soluble |
| 216 | T | A | -1.9709 | Soluble |
| 217 | K | A | -2.4369 | Soluble |
| 218 | V | A | -1.0116 | Soluble |
| 219 | D | A | -1.6006 | Soluble |
| 220 | K | A | -1.5528 | Soluble |
| 221 | K | A | -2.1670 | Soluble |
| 222 | V | A | 0.0000 | Buried |
| 223 | E | A | -2.8920 | Soluble |
| 224 | P | A | -1.9997 | Soluble |
| 225 | K | A | -2.4313 | Soluble |
| 1 | E | B | -1.6959 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.4940 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.5641 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.7169 | Soluble |
| 8 | P | B | -0.5673 | Soluble |
| 9 | G | B | -0.7517 | Soluble |
| 10 | T | B | -0.3951 | Soluble |
| 11 | L | B | -0.2690 | Soluble |
| 12 | S | B | -0.6293 | Soluble |
| 13 | L | B | -1.1040 | Soluble |
| 14 | S | B | -1.6894 | Soluble |
| 15 | P | B | -1.9574 | Soluble |
| 16 | G | B | -2.1971 | Soluble |
| 17 | E | B | -3.0589 | Soluble |
| 18 | R | B | -3.3160 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6403 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.7986 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -1.9366 | Soluble |
| 25 | A | B | -1.0173 | Soluble |
| 26 | S | B | -0.9699 | Soluble |
| 27 | Q | B | -1.7126 | Soluble |
| 28 | T | B | -1.2579 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6549 | Soluble |
| 36 | S | B | -0.2673 | Soluble |
| 37 | T | B | 0.3559 | Aggregation-prone |
| 38 | S | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -0.9083 | Soluble |
| 45 | K | B | -1.5995 | Soluble |
| 46 | P | B | -1.5053 | Soluble |
| 47 | G | B | -1.3265 | Soluble |
| 48 | Q | B | -2.0230 | Soluble |
| 49 | A | B | -1.3002 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.0718 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.4989 | Aggregation-prone |
| 56 | G | B | 0.4833 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.5425 | Soluble |
| 66 | S | B | -0.2348 | Soluble |
| 67 | R | B | -1.1015 | Soluble |
| 68 | A | B | -0.6049 | Soluble |
| 69 | T | B | -0.5308 | Soluble |
| 70 | G | B | -0.8380 | Soluble |
| 71 | I | B | 0.0000 | Buried |
| 72 | P | B | -1.2768 | Soluble |
| 74 | D | B | -2.1596 | Soluble |
| 75 | R | B | -2.0712 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.7864 | Soluble |
| 78 | G | B | -0.4310 | Soluble |
| 79 | S | B | -0.6948 | Soluble |
| 80 | G | B | -1.2056 | Soluble |
| 83 | S | B | -1.0947 | Soluble |
| 84 | G | B | -1.1225 | Soluble |
| 85 | T | B | -1.6005 | Soluble |
| 86 | D | B | -2.0574 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7318 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8170 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.4478 | Soluble |
| 93 | R | B | -3.4215 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.5857 | Soluble |
| 96 | P | B | -1.7727 | Soluble |
| 97 | E | B | -2.3695 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.0859 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | D | B | -1.3449 | Soluble |
| 114 | T | B | -0.9809 | Soluble |
| 115 | S | B | -0.9067 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.2433 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.7001 | Soluble |
| 121 | G | B | -0.7005 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.5026 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -0.6652 | Soluble |
| 127 | K | B | -1.6818 | Soluble |
| 128 | R | B | -0.9431 | Soluble |
| 129 | T | B | 0.0472 | Aggregation-prone |
| 130 | V | B | 0.8191 | Aggregation-prone |
| 131 | A | B | 0.1987 | Aggregation-prone |
| 132 | A | B | 0.0391 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1293 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.1642 | Aggregation-prone |
| 137 | I | B | 0.0910 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4554 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.6117 | Soluble |
| 142 | D | B | -2.7465 | Soluble |
| 143 | E | B | -2.5229 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1402 | Soluble |
| 146 | K | B | -2.7663 | Soluble |
| 147 | S | B | -1.7021 | Soluble |
| 148 | G | B | -1.2362 | Soluble |
| 149 | T | B | -1.1086 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.6817 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.2597 | Soluble |
| 162 | R | B | -2.0677 | Soluble |
| 163 | E | B | -2.8640 | Soluble |
| 164 | A | B | -2.1719 | Soluble |
| 165 | K | B | -2.1706 | Soluble |
| 166 | V | B | -1.2358 | Soluble |
| 167 | Q | B | -0.8160 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.7755 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.9168 | Soluble |
| 172 | N | B | -1.4723 | Soluble |
| 173 | A | B | -0.4538 | Soluble |
| 174 | L | B | 0.3070 | Aggregation-prone |
| 175 | Q | B | -0.3023 | Soluble |
| 176 | S | B | -0.6205 | Soluble |
| 177 | G | B | -0.9485 | Soluble |
| 178 | N | B | -0.8850 | Soluble |
| 179 | S | B | -1.0952 | Soluble |
| 180 | Q | B | -1.3344 | Soluble |
| 181 | E | B | -1.3914 | Soluble |
| 182 | S | B | -0.5575 | Soluble |
| 183 | V | B | -0.6203 | Soluble |
| 184 | T | B | -1.1258 | Soluble |
| 185 | E | B | -2.1603 | Soluble |
| 186 | Q | B | -1.7314 | Soluble |
| 187 | D | B | -1.8458 | Soluble |
| 188 | S | B | -1.6365 | Soluble |
| 189 | K | B | -2.1724 | Soluble |
| 190 | D | B | -1.5009 | Soluble |
| 191 | S | B | -1.5612 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.5961 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4245 | Soluble |
| 201 | L | B | -0.4625 | Soluble |
| 202 | S | B | -0.9962 | Soluble |
| 203 | K | B | -1.8428 | Soluble |
| 204 | A | B | -1.5427 | Soluble |
| 205 | D | B | -1.9011 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -2.7271 | Soluble |
| 208 | K | B | -3.1461 | Soluble |
| 209 | H | B | -2.5802 | Soluble |
| 210 | K | B | -2.6209 | Soluble |
| 211 | V | B | -1.1789 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.8859 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1639 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.3843 | Soluble |
| 220 | G | B | -0.2937 | Soluble |
| 221 | L | B | -0.1613 | Soluble |
| 222 | S | B | -0.4166 | Soluble |
| 223 | S | B | -0.3778 | Soluble |
| 224 | P | B | -0.5429 | Soluble |
| 225 | V | B | 0.1640 | Aggregation-prone |
| 226 | T | B | -0.4568 | Soluble |
| 227 | K | B | -0.7261 | Soluble |
| 228 | S | B | -0.5363 | Soluble |
| 229 | F | B | -0.8096 | Soluble |
| 230 | N | B | -1.7040 | Soluble |
| 231 | R | B | -2.2773 | Soluble |
| 232 | G | B | -1.9945 | Soluble |
| 233 | E | B | -2.6085 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6324 | 5.2255 | CSV PDB |
| 4.5 | -0.6708 | 5.1601 | CSV PDB |
| 5.0 | -0.7163 | 5.0529 | CSV PDB |
| 5.5 | -0.7595 | 4.931 | CSV PDB |
| 6.0 | -0.7898 | 4.8642 | CSV PDB |
| 6.5 | -0.7984 | 4.8056 | CSV PDB |
| 7.0 | -0.7846 | 4.7651 | CSV PDB |
| 7.5 | -0.7559 | 4.7445 | CSV PDB |
| 8.0 | -0.7191 | 4.7363 | CSV PDB |
| 8.5 | -0.6768 | 4.7334 | CSV PDB |
| 9.0 | -0.6293 | 4.7322 | CSV PDB |