Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.4393 | Soluble |
| 2 | V | A | -1.1701 | Soluble |
| 3 | Q | A | -1.6919 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.4217 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.7286 | Soluble |
| 8 | G | A | -0.6465 | Soluble |
| 9 | A | A | -0.1873 | Soluble |
| 11 | E | A | -0.5840 | Soluble |
| 12 | V | A | -0.0275 | Soluble |
| 13 | K | A | -1.3465 | Soluble |
| 14 | K | A | -2.5659 | Soluble |
| 15 | P | A | -2.6656 | Soluble |
| 16 | G | A | -2.3678 | Soluble |
| 17 | A | A | -1.7594 | Soluble |
| 18 | S | A | -2.0130 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.9467 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6670 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.3433 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.9995 | Soluble |
| 27 | G | A | -1.0132 | Soluble |
| 28 | Y | A | -0.4992 | Soluble |
| 29 | P | A | -0.2037 | Soluble |
| 30 | F | A | 0.0857 | Aggregation-prone |
| 35 | T | A | 0.2725 | Aggregation-prone |
| 36 | S | A | 0.3573 | Aggregation-prone |
| 37 | Y | A | 0.4391 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | -0.4675 | Soluble |
| 44 | Q | A | -0.6748 | Soluble |
| 45 | A | A | -0.9968 | Soluble |
| 46 | P | A | -0.8443 | Soluble |
| 47 | G | A | -1.2281 | Soluble |
| 48 | Q | A | -1.7575 | Soluble |
| 49 | G | A | -1.0989 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.6027 | Soluble |
| 52 | W | A | -0.2377 | Soluble |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.4537 | Aggregation-prone |
| 62 | N | A | -0.8938 | Soluble |
| 63 | G | A | -1.2981 | Soluble |
| 64 | N | A | -1.4309 | Soluble |
| 65 | T | A | -1.0527 | Soluble |
| 66 | N | A | -1.0527 | Soluble |
| 67 | Y | A | -1.1444 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | Q | A | -2.5350 | Soluble |
| 70 | K | A | -2.6625 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.3731 | Soluble |
| 74 | G | A | -1.6079 | Soluble |
| 75 | R | A | -1.7686 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.6843 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.3508 | Soluble |
| 80 | T | A | -0.6600 | Soluble |
| 81 | D | A | -0.7438 | Soluble |
| 82 | T | A | -0.4384 | Soluble |
| 83 | S | A | -0.4518 | Soluble |
| 84 | T | A | -0.5853 | Soluble |
| 85 | T | A | -0.7028 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.4885 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.1161 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -2.3661 | Soluble |
| 93 | R | A | -3.1159 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.4622 | Soluble |
| 96 | S | A | -2.5427 | Soluble |
| 97 | D | A | -2.5154 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.8745 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.0985 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.1696 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 0.9187 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.3208 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.3246 | Aggregation-prone |
| 111C | F | A | 1.5194 | Aggregation-prone |
| 112D | G | A | -0.2811 | Soluble |
| 112C | E | A | -1.4563 | Soluble |
| 112B | S | A | -0.7928 | Soluble |
| 112A | L | A | 0.3590 | Aggregation-prone |
| 112 | I | A | 1.7295 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.6883 | Soluble |
| 117 | N | A | -1.2020 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4626 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.1167 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.3621 | Soluble |
| 128 | S | A | -1.0869 | Soluble |
| 129 | A | A | -0.6896 | Soluble |
| 130 | S | A | -0.7431 | Soluble |
| 131 | T | A | -0.7602 | Soluble |
| 132 | K | A | -1.2209 | Soluble |
| 133 | G | A | -1.4062 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.4862 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.2375 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.2411 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.8952 | Soluble |
| 143 | S | A | -0.8548 | Soluble |
| 144 | K | A | -0.9220 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.6925 | Soluble |
| 147 | S | A | -0.7846 | Soluble |
| 148 | G | A | -0.8083 | Soluble |
| 149 | G | A | -0.7943 | Soluble |
| 150 | T | A | -0.5709 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.4758 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | -0.5930 | Soluble |
| 163 | E | A | -0.6418 | Soluble |
| 164 | P | A | -0.7721 | Soluble |
| 165 | V | A | -0.6600 | Soluble |
| 166 | T | A | -0.5387 | Soluble |
| 167 | V | A | -0.1054 | Soluble |
| 168 | S | A | -0.1645 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.7495 | Soluble |
| 171 | S | A | -0.6669 | Soluble |
| 172 | G | A | -0.5937 | Soluble |
| 173 | A | A | -0.2584 | Soluble |
| 174 | L | A | 0.0133 | Aggregation-prone |
| 175 | T | A | -0.1462 | Soluble |
| 176 | S | A | -0.3549 | Soluble |
| 177 | G | A | -0.1751 | Soluble |
| 178 | V | A | 0.1483 | Aggregation-prone |
| 179 | H | A | -0.3384 | Soluble |
| 180 | T | A | -0.0211 | Soluble |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3660 | Soluble |
| 183 | A | A | 0.0667 | Aggregation-prone |
| 184 | V | A | 0.4394 | Aggregation-prone |
| 185 | L | A | 1.2599 | Aggregation-prone |
| 186 | Q | A | 0.2756 | Aggregation-prone |
| 187 | S | A | -0.0673 | Soluble |
| 188 | S | A | -0.1963 | Soluble |
| 189 | G | A | 0.0752 | Aggregation-prone |
| 190 | L | A | 0.0806 | Aggregation-prone |
| 191 | Y | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1263 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5266 | Soluble |
| 201 | S | A | -0.5542 | Soluble |
| 202 | S | A | -0.5669 | Soluble |
| 203 | S | A | -0.5860 | Soluble |
| 204 | L | A | -0.7434 | Soluble |
| 205 | G | A | -1.0091 | Soluble |
| 206 | T | A | -0.7481 | Soluble |
| 207 | Q | A | -1.2392 | Soluble |
| 208 | T | A | -1.2623 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.3377 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4679 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | 0.0000 | Buried |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.6095 | Soluble |
| 217 | P | A | -1.6142 | Soluble |
| 218 | S | A | -1.8196 | Soluble |
| 219 | N | A | -2.3077 | Soluble |
| 220 | T | A | -2.0120 | Soluble |
| 221 | K | A | -2.5762 | Soluble |
| 222 | V | A | -1.5512 | Soluble |
| 223 | D | A | -2.6238 | Soluble |
| 224 | K | A | -2.2567 | Soluble |
| 225 | R | A | -2.7776 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.9271 | Soluble |
| 228 | P | A | -2.1597 | Soluble |
| 229 | K | A | -2.2740 | Soluble |
| 1 | E | B | -1.6526 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.4457 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.7570 | Soluble |
| 6 | Q | B | -1.0813 | Soluble |
| 7 | S | B | -0.8800 | Soluble |
| 8 | P | B | -0.5602 | Soluble |
| 9 | G | B | -0.7661 | Soluble |
| 10 | T | B | -0.3818 | Soluble |
| 11 | L | B | -0.1904 | Soluble |
| 12 | S | B | -0.6558 | Soluble |
| 13 | L | B | -1.0740 | Soluble |
| 14 | S | B | -1.4254 | Soluble |
| 15 | P | B | -1.8756 | Soluble |
| 16 | G | B | -2.1708 | Soluble |
| 17 | E | B | -2.9006 | Soluble |
| 18 | R | B | -3.3223 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.5488 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -1.0499 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.4440 | Soluble |
| 25 | A | B | -1.3492 | Soluble |
| 26 | S | B | -1.1852 | Soluble |
| 27 | Q | B | -1.7149 | Soluble |
| 28 | T | B | -1.1006 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6832 | Soluble |
| 36 | S | B | -0.2880 | Soluble |
| 37 | T | B | 0.2165 | Aggregation-prone |
| 38 | S | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.4400 | Soluble |
| 46 | P | B | -1.2518 | Soluble |
| 47 | G | B | -1.4182 | Soluble |
| 48 | Q | B | -2.0441 | Soluble |
| 49 | A | B | -1.4687 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.5998 | Soluble |
| 52 | L | B | -0.6958 | Soluble |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.5124 | Aggregation-prone |
| 56 | G | B | 0.3279 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.5158 | Soluble |
| 66 | S | B | -0.3405 | Soluble |
| 67 | R | B | -0.9635 | Soluble |
| 68 | A | B | -0.5334 | Soluble |
| 69 | T | B | -0.4176 | Soluble |
| 70 | G | B | -0.8189 | Soluble |
| 71 | I | B | -0.8262 | Soluble |
| 72 | P | B | -1.1986 | Soluble |
| 74 | D | B | -2.3022 | Soluble |
| 75 | R | B | -1.9598 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.7857 | Soluble |
| 78 | G | B | -0.3959 | Soluble |
| 79 | S | B | -0.6827 | Soluble |
| 80 | G | B | -1.0643 | Soluble |
| 83 | S | B | -1.0091 | Soluble |
| 84 | G | B | -1.2574 | Soluble |
| 85 | T | B | -1.9213 | Soluble |
| 86 | D | B | -2.7017 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.9201 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.7713 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.3450 | Soluble |
| 93 | R | B | -3.4297 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.2054 | Soluble |
| 96 | P | B | -1.3795 | Soluble |
| 97 | E | B | -2.0417 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.5886 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.0013 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | D | B | -1.3048 | Soluble |
| 114 | T | B | -1.0241 | Soluble |
| 115 | S | B | -0.9073 | Soluble |
| 116 | L | B | -0.2111 | Soluble |
| 117 | T | B | -0.0089 | Soluble |
| 118 | F | B | 0.2829 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.7082 | Soluble |
| 121 | G | B | -0.6272 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.4585 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -1.0487 | Soluble |
| 127 | K | B | -1.7805 | Soluble |
| 128 | R | B | -1.9887 | Soluble |
| 129 | T | B | -0.5135 | Soluble |
| 130 | V | B | 0.1369 | Aggregation-prone |
| 131 | A | B | 0.0455 | Aggregation-prone |
| 132 | A | B | -0.1143 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2623 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4965 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.5998 | Soluble |
| 142 | D | B | -3.0014 | Soluble |
| 143 | E | B | -3.1515 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.0567 | Soluble |
| 146 | K | B | -2.9376 | Soluble |
| 147 | S | B | -1.8153 | Soluble |
| 148 | G | B | -1.2676 | Soluble |
| 149 | T | B | -1.0346 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -1.1137 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.8630 | Soluble |
| 162 | R | B | -2.9476 | Soluble |
| 163 | E | B | -3.1656 | Soluble |
| 164 | A | B | -2.2476 | Soluble |
| 165 | K | B | -2.2593 | Soluble |
| 166 | V | B | -0.9406 | Soluble |
| 167 | Q | B | -0.4948 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5825 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.4707 | Soluble |
| 172 | N | B | -1.2268 | Soluble |
| 173 | A | B | -0.1671 | Soluble |
| 174 | L | B | 0.7746 | Aggregation-prone |
| 175 | Q | B | -0.1772 | Soluble |
| 176 | S | B | -0.4512 | Soluble |
| 177 | G | B | -0.7591 | Soluble |
| 178 | N | B | -0.9150 | Soluble |
| 179 | S | B | -1.1252 | Soluble |
| 180 | Q | B | -1.3692 | Soluble |
| 181 | E | B | -1.9331 | Soluble |
| 182 | S | B | -0.8594 | Soluble |
| 183 | V | B | -0.7893 | Soluble |
| 184 | T | B | -1.1389 | Soluble |
| 185 | E | B | -2.2733 | Soluble |
| 186 | Q | B | -2.0836 | Soluble |
| 187 | D | B | -2.3705 | Soluble |
| 188 | S | B | -2.1086 | Soluble |
| 189 | K | B | -2.9017 | Soluble |
| 190 | D | B | -3.1019 | Soluble |
| 191 | S | B | -2.4943 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | 0.0000 | Buried |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.3503 | Soluble |
| 201 | L | B | -0.7558 | Soluble |
| 202 | S | B | -1.3573 | Soluble |
| 203 | K | B | -2.2236 | Soluble |
| 204 | A | B | -2.0185 | Soluble |
| 205 | D | B | -2.7949 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.8091 | Soluble |
| 208 | K | B | -3.6527 | Soluble |
| 209 | H | B | -2.9211 | Soluble |
| 210 | K | B | -2.8569 | Soluble |
| 211 | V | B | -1.3578 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.6664 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.0851 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.7475 | Soluble |
| 220 | G | B | -0.4429 | Soluble |
| 221 | L | B | -0.2482 | Soluble |
| 222 | S | B | -0.4531 | Soluble |
| 223 | S | B | -0.3674 | Soluble |
| 224 | P | B | -0.4159 | Soluble |
| 225 | V | B | 0.1979 | Aggregation-prone |
| 226 | T | B | -0.1701 | Soluble |
| 227 | K | B | -0.3632 | Soluble |
| 228 | S | B | -0.3250 | Soluble |
| 229 | F | B | -0.9601 | Soluble |
| 230 | N | B | -1.8354 | Soluble |
| 231 | R | B | -2.4715 | Soluble |
| 232 | G | B | -2.0624 | Soluble |
| 233 | E | B | -2.3652 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7084 | 4.8937 | CSV PDB |
| 4.5 | -0.7517 | 4.8096 | CSV PDB |
| 5.0 | -0.8024 | 4.697 | CSV PDB |
| 5.5 | -0.8508 | 4.5748 | CSV PDB |
| 6.0 | -0.8866 | 4.4618 | CSV PDB |
| 6.5 | -0.9014 | 4.377 | CSV PDB |
| 7.0 | -0.8949 | 4.3295 | CSV PDB |
| 7.5 | -0.874 | 4.3095 | CSV PDB |
| 8.0 | -0.8449 | 4.3024 | CSV PDB |
| 8.5 | -0.8099 | 4.3 | CSV PDB |
| 9.0 | -0.7687 | 4.2991 | CSV PDB |