Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.3850 | Soluble |
| 2 | V | A | -0.9640 | Soluble |
| 3 | Q | A | -1.5583 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.2156 | Soluble |
| 6 | Q | A | -0.3666 | Soluble |
| 7 | S | A | -0.7202 | Soluble |
| 8 | G | A | -0.5155 | Soluble |
| 9 | A | A | -0.0965 | Soluble |
| 11 | E | A | -0.6568 | Soluble |
| 12 | V | A | 0.2704 | Aggregation-prone |
| 13 | K | A | -1.2718 | Soluble |
| 14 | K | A | -2.4366 | Soluble |
| 15 | P | A | -2.6507 | Soluble |
| 16 | G | A | -2.4423 | Soluble |
| 17 | A | A | -1.9583 | Soluble |
| 18 | S | A | -2.1715 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.1257 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6004 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.1779 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.9811 | Soluble |
| 27 | G | A | -0.9603 | Soluble |
| 28 | Y | A | -0.4372 | Soluble |
| 29 | P | A | -0.3161 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.1945 | Aggregation-prone |
| 36 | S | A | 0.3453 | Aggregation-prone |
| 37 | Y | A | 0.4864 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | -0.3307 | Soluble |
| 44 | Q | A | -0.6251 | Soluble |
| 45 | A | A | -0.9594 | Soluble |
| 46 | P | A | -0.7952 | Soluble |
| 47 | G | A | -1.2309 | Soluble |
| 48 | Q | A | -1.7550 | Soluble |
| 49 | G | A | -1.1106 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.5573 | Soluble |
| 52 | W | A | -0.2398 | Soluble |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.4495 | Aggregation-prone |
| 62 | N | A | -0.9953 | Soluble |
| 63 | G | A | -1.4402 | Soluble |
| 64 | N | A | -1.6809 | Soluble |
| 65 | T | A | -1.3888 | Soluble |
| 66 | N | A | -1.5096 | Soluble |
| 67 | Y | A | -1.1737 | Soluble |
| 68 | A | A | -1.6216 | Soluble |
| 69 | Q | A | -2.5924 | Soluble |
| 70 | K | A | -2.6788 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.4855 | Soluble |
| 74 | G | A | -1.8775 | Soluble |
| 75 | R | A | -1.8023 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.8049 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.4071 | Soluble |
| 80 | T | A | -0.6120 | Soluble |
| 81 | D | A | -1.0438 | Soluble |
| 82 | T | A | -0.4737 | Soluble |
| 83 | S | A | -0.5293 | Soluble |
| 84 | T | A | -0.6544 | Soluble |
| 85 | T | A | -0.7828 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.4510 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.4659 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -2.7239 | Soluble |
| 93 | R | A | -3.2994 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.5945 | Soluble |
| 96 | S | A | -2.4030 | Soluble |
| 97 | D | A | -2.5019 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.6836 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.3226 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.3589 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 0.7718 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.2669 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.5113 | Aggregation-prone |
| 111C | F | A | 1.5861 | Aggregation-prone |
| 112D | G | A | -0.3654 | Soluble |
| 112C | E | A | -1.4049 | Soluble |
| 112B | S | A | -0.6396 | Soluble |
| 112A | L | A | 0.5215 | Aggregation-prone |
| 112 | I | A | 1.7475 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.8344 | Soluble |
| 117 | N | A | -0.8917 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4391 | Soluble |
| 121 | G | A | -0.5194 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.8316 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.1741 | Soluble |
| 128 | S | A | -0.9191 | Soluble |
| 129 | A | A | -0.7304 | Soluble |
| 130 | S | A | -0.7472 | Soluble |
| 131 | T | A | -0.7540 | Soluble |
| 132 | K | A | -1.3938 | Soluble |
| 133 | G | A | -1.5148 | Soluble |
| 134 | P | A | -0.7752 | Soluble |
| 135 | S | A | -0.6166 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.1707 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.0460 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -1.1135 | Soluble |
| 143 | S | A | -1.5232 | Soluble |
| 144 | K | A | -1.9682 | Soluble |
| 145 | S | A | -1.3004 | Soluble |
| 146 | T | A | -1.0754 | Soluble |
| 147 | S | A | -0.8126 | Soluble |
| 148 | G | A | -0.7479 | Soluble |
| 149 | G | A | -0.8658 | Soluble |
| 150 | T | A | -0.5154 | Soluble |
| 151 | A | A | -0.4759 | Soluble |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.8632 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | -0.7926 | Soluble |
| 163 | E | A | -0.7035 | Soluble |
| 164 | P | A | -0.8663 | Soluble |
| 165 | V | A | -0.6928 | Soluble |
| 166 | T | A | -0.5396 | Soluble |
| 167 | V | A | -0.0966 | Soluble |
| 168 | S | A | -0.2560 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.6528 | Soluble |
| 171 | S | A | -0.5565 | Soluble |
| 172 | G | A | -0.5763 | Soluble |
| 173 | A | A | -0.1448 | Soluble |
| 174 | L | A | 0.0756 | Aggregation-prone |
| 175 | T | A | -0.1757 | Soluble |
| 176 | S | A | -0.2173 | Soluble |
| 177 | G | A | -0.1531 | Soluble |
| 178 | V | A | 0.2265 | Aggregation-prone |
| 179 | H | A | -0.2200 | Soluble |
| 180 | T | A | 0.0000 | Buried |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.4942 | Soluble |
| 183 | A | A | 0.0285 | Aggregation-prone |
| 184 | V | A | 0.2512 | Aggregation-prone |
| 185 | L | A | 0.7875 | Aggregation-prone |
| 186 | Q | A | -0.0414 | Soluble |
| 187 | S | A | -0.1876 | Soluble |
| 188 | S | A | -0.3882 | Soluble |
| 189 | G | A | -0.2526 | Soluble |
| 190 | L | A | 0.0000 | Buried |
| 191 | Y | A | 0.1104 | Aggregation-prone |
| 192 | S | A | 0.0460 | Aggregation-prone |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | -0.0344 | Soluble |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1058 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5308 | Soluble |
| 201 | S | A | -0.7457 | Soluble |
| 202 | S | A | -0.6197 | Soluble |
| 203 | S | A | -0.6993 | Soluble |
| 204 | L | A | -0.9579 | Soluble |
| 205 | G | A | -1.1176 | Soluble |
| 206 | T | A | -0.8632 | Soluble |
| 207 | Q | A | -1.5119 | Soluble |
| 208 | T | A | -1.2154 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.1216 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | 0.0000 | Buried |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -2.0558 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.8409 | Soluble |
| 217 | P | A | -1.7140 | Soluble |
| 218 | S | A | -1.9049 | Soluble |
| 219 | N | A | -2.6138 | Soluble |
| 220 | T | A | -2.2974 | Soluble |
| 221 | K | A | -2.8453 | Soluble |
| 222 | V | A | -1.8247 | Soluble |
| 223 | D | A | -2.6260 | Soluble |
| 224 | K | A | -2.0629 | Soluble |
| 225 | K | A | -2.5099 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.8202 | Soluble |
| 228 | P | A | -2.0292 | Soluble |
| 229 | K | A | -2.3237 | Soluble |
| 1 | E | B | -1.5823 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.7350 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.5660 | Soluble |
| 6 | Q | B | -0.9902 | Soluble |
| 7 | S | B | -0.9416 | Soluble |
| 8 | P | B | -0.7109 | Soluble |
| 9 | G | B | -0.9419 | Soluble |
| 10 | T | B | -0.7376 | Soluble |
| 11 | L | B | -0.4769 | Soluble |
| 12 | S | B | -0.6877 | Soluble |
| 13 | L | B | -1.0791 | Soluble |
| 14 | S | B | -1.7146 | Soluble |
| 15 | P | B | -1.8524 | Soluble |
| 16 | G | B | -2.3942 | Soluble |
| 17 | E | B | -2.9894 | Soluble |
| 18 | R | B | -3.1850 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.5243 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -1.0670 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.5765 | Soluble |
| 25 | A | B | -1.3500 | Soluble |
| 26 | S | B | -1.1402 | Soluble |
| 27 | Q | B | -1.5773 | Soluble |
| 28 | T | B | -1.4259 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6959 | Soluble |
| 36 | S | B | -0.3398 | Soluble |
| 37 | T | B | 0.1763 | Aggregation-prone |
| 38 | S | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.2318 | Soluble |
| 46 | P | B | -1.1999 | Soluble |
| 47 | G | B | -1.3960 | Soluble |
| 48 | Q | B | -1.9685 | Soluble |
| 49 | A | B | -1.3405 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.2469 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.2380 | Aggregation-prone |
| 56 | G | B | 0.2161 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.6196 | Soluble |
| 66 | S | B | -0.7049 | Soluble |
| 67 | R | B | -1.5427 | Soluble |
| 68 | A | B | -0.8450 | Soluble |
| 69 | T | B | -0.6641 | Soluble |
| 70 | G | B | -0.8915 | Soluble |
| 71 | I | B | 0.0000 | Buried |
| 72 | P | B | -1.3882 | Soluble |
| 74 | D | B | -2.4481 | Soluble |
| 75 | R | B | -2.0096 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -1.0137 | Soluble |
| 78 | G | B | -0.5284 | Soluble |
| 79 | S | B | -0.7679 | Soluble |
| 80 | G | B | -1.2575 | Soluble |
| 83 | S | B | -1.0491 | Soluble |
| 84 | G | B | -1.3521 | Soluble |
| 85 | T | B | -2.0401 | Soluble |
| 86 | D | B | -2.7218 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.9245 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8418 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.4391 | Soluble |
| 93 | R | B | -3.4660 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -1.9231 | Soluble |
| 96 | P | B | -1.4996 | Soluble |
| 97 | E | B | -1.8084 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.6539 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.4353 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | D | B | -1.1392 | Soluble |
| 114 | T | B | -1.1340 | Soluble |
| 115 | S | B | -0.9332 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.0700 | Soluble |
| 118 | F | B | 0.2898 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.6233 | Soluble |
| 121 | G | B | -0.8061 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.1799 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -0.8858 | Soluble |
| 126 | I | B | -0.7821 | Soluble |
| 127 | K | B | -1.6617 | Soluble |
| 128 | R | B | -1.1847 | Soluble |
| 129 | T | B | 0.0731 | Aggregation-prone |
| 130 | V | B | 1.1847 | Aggregation-prone |
| 131 | A | B | 0.5086 | Aggregation-prone |
| 132 | A | B | 0.0800 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1549 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0664 | Aggregation-prone |
| 137 | I | B | 0.0950 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.5128 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.8597 | Soluble |
| 142 | D | B | -3.0664 | Soluble |
| 143 | E | B | -3.2769 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.0891 | Soluble |
| 146 | K | B | -2.8615 | Soluble |
| 147 | S | B | -1.7472 | Soluble |
| 148 | G | B | -1.1533 | Soluble |
| 149 | T | B | -0.9585 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | -0.4430 | Soluble |
| 158 | N | B | -0.8299 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | -0.7727 | Soluble |
| 161 | P | B | -1.4241 | Soluble |
| 162 | R | B | -2.7324 | Soluble |
| 163 | E | B | -3.0175 | Soluble |
| 164 | A | B | -2.1609 | Soluble |
| 165 | K | B | -2.0704 | Soluble |
| 166 | V | B | -0.8065 | Soluble |
| 167 | Q | B | -0.3505 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5616 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.4418 | Soluble |
| 172 | N | B | -1.4484 | Soluble |
| 173 | A | B | -0.1868 | Soluble |
| 174 | L | B | 0.6951 | Aggregation-prone |
| 175 | Q | B | -0.1599 | Soluble |
| 176 | S | B | -0.4825 | Soluble |
| 177 | G | B | -0.9640 | Soluble |
| 178 | N | B | -0.9106 | Soluble |
| 179 | S | B | -1.3387 | Soluble |
| 180 | Q | B | -1.7233 | Soluble |
| 181 | E | B | -2.1063 | Soluble |
| 182 | S | B | -0.9408 | Soluble |
| 183 | V | B | -0.8280 | Soluble |
| 184 | T | B | -1.1582 | Soluble |
| 185 | E | B | -2.2597 | Soluble |
| 186 | Q | B | -1.9371 | Soluble |
| 187 | D | B | -2.0469 | Soluble |
| 188 | S | B | -1.7354 | Soluble |
| 189 | K | B | -2.2275 | Soluble |
| 190 | D | B | -1.6753 | Soluble |
| 191 | S | B | -1.7757 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | -0.6268 | Soluble |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7806 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.2610 | Soluble |
| 201 | L | B | -0.5009 | Soluble |
| 202 | S | B | -1.1150 | Soluble |
| 203 | K | B | -2.1132 | Soluble |
| 204 | A | B | -1.9593 | Soluble |
| 205 | D | B | -3.1736 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.7314 | Soluble |
| 208 | K | B | -3.6756 | Soluble |
| 209 | H | B | -2.9406 | Soluble |
| 210 | K | B | -2.5532 | Soluble |
| 211 | V | B | -1.1207 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | 0.0000 | Buried |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -0.9444 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5989 | Soluble |
| 220 | G | B | -0.2139 | Soluble |
| 221 | L | B | -0.1671 | Soluble |
| 222 | S | B | -0.4328 | Soluble |
| 223 | S | B | -0.3940 | Soluble |
| 224 | P | B | -0.3453 | Soluble |
| 225 | V | B | 0.0483 | Aggregation-prone |
| 226 | T | B | -0.4567 | Soluble |
| 227 | K | B | -0.9423 | Soluble |
| 228 | S | B | -0.7534 | Soluble |
| 229 | F | B | -0.7682 | Soluble |
| 230 | N | B | -1.6459 | Soluble |
| 231 | R | B | -1.6866 | Soluble |
| 232 | G | B | -1.0774 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.723 | 5.3404 | CSV PDB |
| 4.5 | -0.7662 | 5.2651 | CSV PDB |
| 5.0 | -0.8171 | 5.1563 | CSV PDB |
| 5.5 | -0.8655 | 5.0322 | CSV PDB |
| 6.0 | -0.9 | 4.9407 | CSV PDB |
| 6.5 | -0.9115 | 4.8919 | CSV PDB |
| 7.0 | -0.8994 | 4.8621 | CSV PDB |
| 7.5 | -0.8716 | 4.8486 | CSV PDB |
| 8.0 | -0.8352 | 4.8436 | CSV PDB |
| 8.5 | -0.7926 | 4.8418 | CSV PDB |
| 9.0 | -0.7439 | 4.8408 | CSV PDB |