Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAVSGYSITSGYSWNWIRQAPGKGLEWVASITYDGSTNYNPSVKGRITISRDDSKNTFYLQMNSLRAEDTAVYYCARGSHYFGHWHFAVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKDIQLTQSPSSLSASVGDRVTITCRASQSVDYDGDSYMNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSHEDPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1518 | Soluble |
| 2 | V | A | -1.3394 | Soluble |
| 3 | Q | A | -1.4069 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.8766 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.4985 | Soluble |
| 8 | G | A | -1.1044 | Soluble |
| 9 | G | A | -0.6004 | Soluble |
| 11 | G | A | -0.3182 | Soluble |
| 12 | L | A | -0.0615 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.6412 | Soluble |
| 15 | P | A | -1.5457 | Soluble |
| 16 | G | A | -1.5007 | Soluble |
| 17 | G | A | -1.3008 | Soluble |
| 18 | S | A | -1.7007 | Soluble |
| 19 | L | A | 0.0000 | Buried |
| 20 | R | A | -2.4656 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.5905 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.1814 | Soluble |
| 25 | V | A | 0.0000 | Buried |
| 26 | S | A | -0.8244 | Soluble |
| 27 | G | A | -1.2585 | Soluble |
| 28 | Y | A | -0.5701 | Soluble |
| 29 | S | A | -0.4087 | Soluble |
| 30 | I | A | 0.0000 | Buried |
| 31 | T | A | -0.5036 | Soluble |
| 35 | S | A | 0.0728 | Aggregation-prone |
| 36 | G | A | 0.0000 | Buried |
| 37 | Y | A | 0.1317 | Aggregation-prone |
| 38 | S | A | 0.0000 | Buried |
| 39 | W | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | I | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.7142 | Soluble |
| 45 | A | A | -1.1546 | Soluble |
| 46 | P | A | -0.9620 | Soluble |
| 47 | G | A | -1.4626 | Soluble |
| 48 | K | A | -2.3794 | Soluble |
| 49 | G | A | -1.6320 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.8996 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | S | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | T | A | -0.1418 | Soluble |
| 58 | Y | A | 0.3199 | Aggregation-prone |
| 59 | D | A | -1.3316 | Soluble |
| 63 | G | A | -0.9750 | Soluble |
| 64 | S | A | -0.7202 | Soluble |
| 65 | T | A | -0.4876 | Soluble |
| 66 | N | A | -0.8870 | Soluble |
| 67 | Y | A | -0.9063 | Soluble |
| 68 | N | A | 0.0000 | Buried |
| 69 | P | A | -1.4249 | Soluble |
| 70 | S | A | -0.9153 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.1873 | Soluble |
| 74 | G | A | -1.6092 | Soluble |
| 75 | R | A | -1.5252 | Soluble |
| 76 | I | A | 0.0000 | Buried |
| 77 | T | A | -1.0720 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.7353 | Soluble |
| 80 | R | A | -1.4715 | Soluble |
| 81 | D | A | -2.2131 | Soluble |
| 82 | D | A | -2.5290 | Soluble |
| 83 | S | A | -2.0551 | Soluble |
| 84 | K | A | -2.6220 | Soluble |
| 85 | N | A | -1.9492 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | F | A | 0.0000 | Buried |
| 88 | Y | A | -0.7845 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.7494 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.9051 | Soluble |
| 93 | S | A | -1.4114 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.4442 | Soluble |
| 96 | A | A | -1.7438 | Soluble |
| 97 | E | A | -2.2603 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.6943 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2372 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.1960 | Soluble |
| 107 | G | A | 0.0000 | Buried |
| 108 | S | A | 0.1104 | Aggregation-prone |
| 109 | H | A | -0.1057 | Soluble |
| 110 | Y | A | 1.2637 | Aggregation-prone |
| 111 | F | A | 1.4160 | Aggregation-prone |
| 112A | G | A | 0.3883 | Aggregation-prone |
| 112 | H | A | 0.2021 | Aggregation-prone |
| 113 | W | A | -0.2530 | Soluble |
| 114 | H | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | A | A | -0.1636 | Soluble |
| 117 | V | A | -0.0828 | Soluble |
| 118 | W | A | -0.4486 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3726 | Soluble |
| 121 | G | A | -0.5950 | Soluble |
| 122 | T | A | -0.0838 | Soluble |
| 123 | L | A | 0.1452 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.3952 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.7393 | Soluble |
| 128 | S | A | -0.6921 | Soluble |
| 129 | A | A | -0.5127 | Soluble |
| 130 | S | A | -0.6522 | Soluble |
| 131 | T | A | -1.0587 | Soluble |
| 132 | K | A | -1.5658 | Soluble |
| 133 | G | A | -1.6858 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3595 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.4819 | Soluble |
| 138 | P | A | -0.9000 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.9947 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.9385 | Soluble |
| 143 | S | A | -1.5411 | Soluble |
| 144 | K | A | -1.9614 | Soluble |
| 145 | S | A | -1.3710 | Soluble |
| 146 | T | A | -0.9140 | Soluble |
| 147 | S | A | -0.7931 | Soluble |
| 148 | G | A | -1.1033 | Soluble |
| 149 | G | A | -0.6719 | Soluble |
| 150 | T | A | -0.4851 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.7064 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.6034 | Soluble |
| 164 | P | A | -0.7830 | Soluble |
| 165 | V | A | -0.7551 | Soluble |
| 166 | T | A | -0.6487 | Soluble |
| 167 | V | A | -0.2717 | Soluble |
| 168 | S | A | -0.4336 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.7429 | Soluble |
| 171 | S | A | -0.6752 | Soluble |
| 172 | G | A | -0.5368 | Soluble |
| 173 | A | A | -0.2481 | Soluble |
| 174 | L | A | -0.0119 | Soluble |
| 175 | T | A | -0.1664 | Soluble |
| 176 | S | A | -0.1842 | Soluble |
| 177 | G | A | -0.2263 | Soluble |
| 178 | V | A | 0.1757 | Aggregation-prone |
| 179 | H | A | 0.0000 | Buried |
| 180 | T | A | -0.0770 | Soluble |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3410 | Soluble |
| 183 | A | A | 0.1623 | Aggregation-prone |
| 184 | V | A | 0.4350 | Aggregation-prone |
| 185 | L | A | 1.1418 | Aggregation-prone |
| 186 | Q | A | 0.2061 | Aggregation-prone |
| 187 | S | A | -0.0847 | Soluble |
| 188 | S | A | -0.2730 | Soluble |
| 189 | G | A | -0.0484 | Soluble |
| 190 | L | A | -0.0168 | Soluble |
| 191 | Y | A | 0.3384 | Aggregation-prone |
| 192 | S | A | 0.1701 | Aggregation-prone |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1166 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.4708 | Soluble |
| 201 | S | A | -0.7928 | Soluble |
| 202 | S | A | -0.6029 | Soluble |
| 203 | S | A | -0.4985 | Soluble |
| 204 | L | A | -0.7798 | Soluble |
| 205 | G | A | -0.9496 | Soluble |
| 206 | T | A | -0.6010 | Soluble |
| 207 | Q | A | -0.9446 | Soluble |
| 208 | T | A | -0.9602 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.2192 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4756 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -2.1782 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.8330 | Soluble |
| 217 | P | A | -1.6687 | Soluble |
| 218 | S | A | -1.9828 | Soluble |
| 219 | N | A | -2.6828 | Soluble |
| 220 | T | A | -2.2058 | Soluble |
| 221 | K | A | -2.7987 | Soluble |
| 222 | V | A | -1.6423 | Soluble |
| 223 | D | A | -2.5471 | Soluble |
| 224 | K | A | -2.1122 | Soluble |
| 225 | K | A | -2.4112 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.7819 | Soluble |
| 228 | P | A | -2.1555 | Soluble |
| 229 | K | A | -2.3604 | Soluble |
| 1 | D | B | -2.8656 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | Q | B | -2.2670 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -1.4160 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.7777 | Soluble |
| 8 | P | B | -0.7397 | Soluble |
| 9 | S | B | -1.0550 | Soluble |
| 10 | S | B | -1.0299 | Soluble |
| 11 | L | B | -0.7172 | Soluble |
| 12 | S | B | -0.7657 | Soluble |
| 13 | A | B | -1.1383 | Soluble |
| 14 | S | B | -1.1671 | Soluble |
| 15 | V | B | -0.3956 | Soluble |
| 16 | G | B | -1.0920 | Soluble |
| 17 | D | B | -2.4484 | Soluble |
| 18 | R | B | -2.6797 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.6821 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.7981 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.6739 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -2.0077 | Soluble |
| 27 | Q | B | -2.3254 | Soluble |
| 28 | S | B | -1.3128 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | D | B | -1.1953 | Soluble |
| 31 | Y | B | -0.3389 | Soluble |
| 34 | D | B | -1.7410 | Soluble |
| 35 | G | B | -1.3533 | Soluble |
| 36 | D | B | -0.8684 | Soluble |
| 37 | S | B | 0.0000 | Buried |
| 38 | Y | B | -0.2182 | Soluble |
| 39 | M | B | 0.0000 | Buried |
| 40 | N | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.3282 | Soluble |
| 45 | K | B | -1.7938 | Soluble |
| 46 | P | B | -1.2989 | Soluble |
| 47 | G | B | -1.7525 | Soluble |
| 48 | K | B | -2.5369 | Soluble |
| 49 | A | B | -1.5939 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.5237 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.8231 | Aggregation-prone |
| 56 | A | B | 0.0000 | Buried |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | 0.2346 | Aggregation-prone |
| 66 | Y | B | 1.2041 | Aggregation-prone |
| 67 | L | B | 0.7222 | Aggregation-prone |
| 68 | E | B | -0.1076 | Soluble |
| 69 | S | B | -0.2966 | Soluble |
| 70 | G | B | -0.5250 | Soluble |
| 71 | V | B | -0.3805 | Soluble |
| 72 | P | B | -0.3522 | Soluble |
| 74 | S | B | -0.4752 | Soluble |
| 75 | R | B | -0.8164 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.1832 | Soluble |
| 78 | G | B | -0.0325 | Soluble |
| 79 | S | B | -0.4980 | Soluble |
| 80 | G | B | -0.9582 | Soluble |
| 83 | S | B | -1.0012 | Soluble |
| 84 | G | B | -1.1627 | Soluble |
| 85 | T | B | -1.7251 | Soluble |
| 86 | D | B | -1.9675 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7060 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6520 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.5418 | Soluble |
| 93 | S | B | -1.4654 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.1889 | Soluble |
| 96 | P | B | -1.5573 | Soluble |
| 97 | E | B | -2.3244 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -1.1511 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -1.0486 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | S | B | 0.0000 | Buried |
| 108 | H | B | -1.4339 | Soluble |
| 109 | E | B | -2.8504 | Soluble |
| 114 | D | B | -2.5909 | Soluble |
| 115 | P | B | 0.0000 | Buried |
| 116 | Y | B | 0.0000 | Buried |
| 117 | T | B | -1.2960 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.8737 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -2.0130 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.0623 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.4849 | Soluble |
| 128 | R | B | -0.8412 | Soluble |
| 129 | T | B | -0.0744 | Soluble |
| 130 | V | B | 0.6441 | Aggregation-prone |
| 131 | A | B | 0.2085 | Aggregation-prone |
| 132 | A | B | -0.0639 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.0827 | Soluble |
| 135 | V | B | 0.0831 | Aggregation-prone |
| 136 | F | B | 0.2366 | Aggregation-prone |
| 137 | I | B | 0.1735 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4510 | Soluble |
| 140 | P | B | -0.6790 | Soluble |
| 141 | S | B | -1.4928 | Soluble |
| 142 | D | B | -2.6377 | Soluble |
| 143 | E | B | -2.0234 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.9898 | Soluble |
| 146 | K | B | -2.4938 | Soluble |
| 147 | S | B | -1.5694 | Soluble |
| 148 | G | B | -1.1895 | Soluble |
| 149 | T | B | -0.9400 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8588 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.8066 | Soluble |
| 162 | R | B | -3.1908 | Soluble |
| 163 | E | B | -3.2518 | Soluble |
| 164 | A | B | -2.3302 | Soluble |
| 165 | K | B | -2.3609 | Soluble |
| 166 | V | B | -1.1092 | Soluble |
| 167 | Q | B | -0.5150 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5795 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -2.0570 | Soluble |
| 172 | N | B | -1.4331 | Soluble |
| 173 | A | B | -0.3050 | Soluble |
| 174 | L | B | 0.7664 | Aggregation-prone |
| 175 | Q | B | -0.0422 | Soluble |
| 176 | S | B | -0.3510 | Soluble |
| 177 | G | B | -0.9218 | Soluble |
| 178 | N | B | -0.8573 | Soluble |
| 179 | S | B | -1.2024 | Soluble |
| 180 | Q | B | -1.5240 | Soluble |
| 181 | E | B | -2.0326 | Soluble |
| 182 | S | B | -1.0442 | Soluble |
| 183 | V | B | -0.8098 | Soluble |
| 184 | T | B | 0.0000 | Buried |
| 185 | E | B | -1.8219 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -1.9265 | Soluble |
| 188 | S | B | -2.0592 | Soluble |
| 189 | K | B | -2.3984 | Soluble |
| 190 | D | B | -1.7392 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7210 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4308 | Soluble |
| 201 | L | B | -0.6449 | Soluble |
| 202 | S | B | -1.2024 | Soluble |
| 203 | K | B | -2.0475 | Soluble |
| 204 | A | B | -1.8716 | Soluble |
| 205 | D | B | -2.4924 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.4968 | Soluble |
| 208 | K | B | -3.6464 | Soluble |
| 209 | H | B | -3.0131 | Soluble |
| 210 | K | B | -2.9826 | Soluble |
| 211 | V | B | -1.3329 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -1.0072 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2481 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.7199 | Soluble |
| 220 | G | B | -0.4145 | Soluble |
| 221 | L | B | -0.2289 | Soluble |
| 222 | S | B | -0.4704 | Soluble |
| 223 | S | B | -0.4466 | Soluble |
| 224 | P | B | -0.6251 | Soluble |
| 225 | V | B | -0.0929 | Soluble |
| 226 | T | B | -0.4864 | Soluble |
| 227 | K | B | -0.5697 | Soluble |
| 228 | S | B | -0.4666 | Soluble |
| 229 | F | B | -0.7043 | Soluble |
| 230 | N | B | -1.6261 | Soluble |
| 231 | R | B | -2.3184 | Soluble |
| 232 | G | B | -2.0792 | Soluble |
| 233 | E | B | -2.1129 | Soluble |
| 234 | C | B | -1.0214 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7553 | 2.0279 | CSV PDB |
| 4.5 | -0.8033 | 2.0239 | CSV PDB |
| 5.0 | -0.8581 | 2.0295 | CSV PDB |
| 5.5 | -0.9092 | 2.0539 | CSV PDB |
| 6.0 | -0.9455 | 2.098 | CSV PDB |
| 6.5 | -0.9582 | 2.1476 | CSV PDB |
| 7.0 | -0.9475 | 2.1838 | CSV PDB |
| 7.5 | -0.9214 | 2.1995 | CSV PDB |
| 8.0 | -0.8866 | 2.1994 | CSV PDB |
| 8.5 | -0.8446 | 2.1908 | CSV PDB |
| 9.0 | -0.7954 | 2.1768 | CSV PDB |