Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPDIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | B | -2.1749 | Soluble |
| 2 | V | B | -1.4411 | Soluble |
| 3 | Q | B | -1.3280 | Soluble |
| 4 | L | B | -0.0833 | Soluble |
| 5 | V | B | 1.1187 | Aggregation-prone |
| 6 | E | B | 0.1295 | Aggregation-prone |
| 7 | S | B | -0.2634 | Soluble |
| 8 | G | B | -0.6338 | Soluble |
| 9 | G | B | -0.2635 | Soluble |
| 11 | G | B | -0.2516 | Soluble |
| 12 | L | B | -0.1852 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | Q | B | -1.6227 | Soluble |
| 15 | P | B | -1.6763 | Soluble |
| 16 | G | B | -1.3554 | Soluble |
| 17 | G | B | -1.0989 | Soluble |
| 18 | S | B | -1.0137 | Soluble |
| 19 | L | B | -0.8587 | Soluble |
| 20 | R | B | -1.5190 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.2025 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.0253 | Soluble |
| 25 | A | B | -0.4674 | Soluble |
| 26 | S | B | -0.9459 | Soluble |
| 27 | G | B | -1.5662 | Soluble |
| 28 | F | B | -1.4928 | Soluble |
| 29 | N | B | -2.1566 | Soluble |
| 30 | I | B | 0.0000 | Buried |
| 35 | K | B | -2.9790 | Soluble |
| 36 | D | B | -2.7919 | Soluble |
| 37 | T | B | 0.0000 | Buried |
| 38 | Y | B | -0.4255 | Soluble |
| 39 | I | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | -0.8673 | Soluble |
| 44 | Q | B | -1.0889 | Soluble |
| 45 | A | B | -1.4693 | Soluble |
| 46 | P | B | -1.1974 | Soluble |
| 47 | G | B | -1.4551 | Soluble |
| 48 | K | B | -2.5703 | Soluble |
| 49 | G | B | -2.0058 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -2.1697 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | A | B | 0.0000 | Buried |
| 55 | R | B | -0.5022 | Soluble |
| 56 | I | B | 0.0000 | Buried |
| 57 | Y | B | -0.3240 | Soluble |
| 58 | P | B | 0.0000 | Buried |
| 59 | T | B | -1.4663 | Soluble |
| 62 | N | B | -1.3099 | Soluble |
| 63 | G | B | -0.4505 | Soluble |
| 64 | Y | B | 0.4860 | Aggregation-prone |
| 65 | T | B | -0.3691 | Soluble |
| 66 | R | B | -1.6419 | Soluble |
| 67 | Y | B | -1.7047 | Soluble |
| 68 | A | B | -1.9543 | Soluble |
| 69 | D | B | -2.6646 | Soluble |
| 70 | S | B | -1.6870 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -2.8675 | Soluble |
| 74 | G | B | -1.8243 | Soluble |
| 75 | R | B | -1.4266 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -0.9962 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.3385 | Soluble |
| 80 | A | B | -0.9846 | Soluble |
| 81 | D | B | -2.2613 | Soluble |
| 82 | T | B | -2.3049 | Soluble |
| 83 | S | B | -1.8202 | Soluble |
| 84 | K | B | -2.3099 | Soluble |
| 85 | N | B | -2.0617 | Soluble |
| 86 | T | B | 0.0000 | Buried |
| 87 | A | B | 0.0000 | Buried |
| 88 | Y | B | -0.5558 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.0932 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -1.3084 | Soluble |
| 93 | S | B | -1.2251 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | R | B | -2.1654 | Soluble |
| 96 | A | B | -1.7214 | Soluble |
| 97 | E | B | -2.2167 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.7313 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.0611 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | S | B | 0.0000 | Buried |
| 106 | R | B | -0.0415 | Soluble |
| 107 | W | B | 0.0000 | Buried |
| 108 | G | B | -0.6612 | Soluble |
| 109 | G | B | -1.5697 | Soluble |
| 110 | D | B | -2.0791 | Soluble |
| 111 | G | B | -1.0791 | Soluble |
| 112 | F | B | -0.2334 | Soluble |
| 113 | Y | B | 0.1004 | Aggregation-prone |
| 114 | A | B | 0.0000 | Buried |
| 115 | M | B | 0.0000 | Buried |
| 116 | D | B | 0.0000 | Buried |
| 117 | Y | B | -0.2628 | Soluble |
| 118 | W | B | 0.0000 | Buried |
| 119 | G | B | -0.6948 | Soluble |
| 120 | Q | B | -1.4105 | Soluble |
| 121 | G | B | -0.7311 | Soluble |
| 122 | T | B | -0.0983 | Soluble |
| 123 | L | B | 0.2439 | Aggregation-prone |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -0.9297 | Soluble |
| 128 | S | B | -0.8082 | Soluble |
| 129 | A | B | -0.5829 | Soluble |
| 130 | S | B | -0.7155 | Soluble |
| 131 | T | B | -1.1045 | Soluble |
| 132 | K | B | -1.7593 | Soluble |
| 133 | G | B | -1.8073 | Soluble |
| 134 | P | B | 0.0000 | Buried |
| 135 | S | B | -0.3768 | Soluble |
| 136 | V | B | -0.4928 | Soluble |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.1647 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | -0.8691 | Soluble |
| 141 | P | B | -0.8183 | Soluble |
| 142 | S | B | -0.9890 | Soluble |
| 143 | S | B | -1.1619 | Soluble |
| 144 | K | B | -1.9617 | Soluble |
| 145 | S | B | 0.0000 | Buried |
| 146 | T | B | -0.8932 | Soluble |
| 147 | S | B | -0.7512 | Soluble |
| 148 | G | B | -0.8410 | Soluble |
| 149 | G | B | -0.9294 | Soluble |
| 150 | T | B | -0.6523 | Soluble |
| 151 | A | B | 0.0000 | Buried |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.8243 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | 0.0000 | Buried |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.6296 | Soluble |
| 164 | P | B | -0.7858 | Soluble |
| 165 | V | B | 0.0000 | Buried |
| 166 | T | B | -0.7002 | Soluble |
| 167 | V | B | -0.4550 | Soluble |
| 168 | S | B | -0.3996 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.5032 | Soluble |
| 171 | S | B | -0.4982 | Soluble |
| 172 | G | B | -0.2641 | Soluble |
| 173 | A | B | 0.2276 | Aggregation-prone |
| 174 | L | B | 1.1484 | Aggregation-prone |
| 175 | T | B | 0.4419 | Aggregation-prone |
| 176 | S | B | 0.2467 | Aggregation-prone |
| 177 | G | B | 0.0278 | Aggregation-prone |
| 178 | V | B | 0.4506 | Aggregation-prone |
| 179 | H | B | -0.2113 | Soluble |
| 180 | T | B | -0.0883 | Soluble |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.1506 | Soluble |
| 183 | A | B | 0.2252 | Aggregation-prone |
| 184 | V | B | 0.2294 | Aggregation-prone |
| 185 | L | B | 0.5469 | Aggregation-prone |
| 186 | Q | B | -0.2292 | Soluble |
| 187 | S | B | -0.3321 | Soluble |
| 188 | S | B | -0.2800 | Soluble |
| 189 | G | B | -0.0713 | Soluble |
| 190 | L | B | -0.1760 | Soluble |
| 191 | Y | B | 0.2121 | Aggregation-prone |
| 192 | S | B | 0.0000 | Buried |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1416 | Soluble |
| 199 | V | B | -0.0847 | Soluble |
| 200 | P | B | -0.5501 | Soluble |
| 201 | S | B | -0.7052 | Soluble |
| 202 | S | B | -0.6160 | Soluble |
| 203 | S | B | -0.5912 | Soluble |
| 204 | L | B | -0.7741 | Soluble |
| 205 | G | B | -1.0977 | Soluble |
| 206 | T | B | -0.8319 | Soluble |
| 207 | Q | B | -1.4543 | Soluble |
| 208 | T | B | -1.3698 | Soluble |
| 209 | Y | B | -0.9739 | Soluble |
| 210 | I | B | -1.3351 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.7593 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.0672 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8361 | Soluble |
| 217 | P | B | -1.6887 | Soluble |
| 218 | S | B | -2.0487 | Soluble |
| 219 | N | B | -2.6171 | Soluble |
| 220 | T | B | -2.3842 | Soluble |
| 221 | K | B | -2.7617 | Soluble |
| 222 | V | B | -1.7651 | Soluble |
| 223 | D | B | -2.6352 | Soluble |
| 224 | K | B | -2.2465 | Soluble |
| 225 | K | B | -2.6403 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.5451 | Soluble |
| 228 | P | B | -1.4034 | Soluble |
| 1 | D | A | -1.9982 | Soluble |
| 2 | I | A | -1.6648 | Soluble |
| 3 | Q | A | -2.0914 | Soluble |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -1.3374 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.6168 | Soluble |
| 8 | P | A | -0.5275 | Soluble |
| 9 | S | A | -0.6486 | Soluble |
| 10 | S | A | -0.4128 | Soluble |
| 11 | L | A | -0.3775 | Soluble |
| 12 | S | A | -1.1139 | Soluble |
| 13 | A | A | -1.2931 | Soluble |
| 14 | S | A | -1.0014 | Soluble |
| 15 | V | A | 0.2671 | Aggregation-prone |
| 16 | G | A | -0.7989 | Soluble |
| 17 | D | A | -1.8332 | Soluble |
| 18 | R | A | -2.4039 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | T | A | -0.6040 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | T | A | -0.8624 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.7647 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -2.1784 | Soluble |
| 27 | Q | A | -2.9256 | Soluble |
| 28 | D | A | -2.9217 | Soluble |
| 29 | V | A | 0.0000 | Buried |
| 36 | N | A | -2.0251 | Soluble |
| 37 | T | A | -1.1880 | Soluble |
| 38 | A | A | -0.0497 | Soluble |
| 39 | V | A | 0.0000 | Buried |
| 40 | A | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | Y | A | 0.0000 | Buried |
| 43 | Q | A | -0.7516 | Soluble |
| 44 | Q | A | 0.0000 | Buried |
| 45 | K | A | -1.8763 | Soluble |
| 46 | P | A | -1.4998 | Soluble |
| 47 | G | A | -1.7575 | Soluble |
| 48 | K | A | -2.5298 | Soluble |
| 49 | A | A | -1.7042 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | K | A | -1.2876 | Soluble |
| 52 | L | A | 0.0000 | Buried |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 1.0948 | Aggregation-prone |
| 56 | S | A | 0.3347 | Aggregation-prone |
| 57 | A | A | 0.0000 | Buried |
| 65 | S | A | 0.4954 | Aggregation-prone |
| 66 | F | A | 2.1668 | Aggregation-prone |
| 67 | L | A | 1.4587 | Aggregation-prone |
| 68 | Y | A | 0.9498 | Aggregation-prone |
| 69 | S | A | 0.1326 | Aggregation-prone |
| 70 | G | A | -0.3409 | Soluble |
| 71 | V | A | 0.0022 | Aggregation-prone |
| 72 | P | A | -0.2633 | Soluble |
| 74 | S | A | -0.3772 | Soluble |
| 75 | R | A | -0.8398 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | 0.0037 | Aggregation-prone |
| 78 | G | A | -0.2740 | Soluble |
| 79 | S | A | -1.1720 | Soluble |
| 80 | R | A | -2.5525 | Soluble |
| 83 | S | A | -1.7220 | Soluble |
| 84 | G | A | -1.9580 | Soluble |
| 85 | T | A | -2.4847 | Soluble |
| 86 | D | A | -2.2051 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -1.0178 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | T | A | -0.6569 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -1.3458 | Soluble |
| 93 | S | A | -1.0700 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | Q | A | -1.0318 | Soluble |
| 96 | P | A | -1.6182 | Soluble |
| 97 | E | A | -2.5028 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | F | A | 0.0000 | Buried |
| 100 | A | A | 0.0000 | Buried |
| 101 | T | A | -0.7177 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | Q | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | H | A | 0.3960 | Aggregation-prone |
| 108 | Y | A | 0.5187 | Aggregation-prone |
| 109 | T | A | 0.1907 | Aggregation-prone |
| 114 | T | A | -0.3490 | Soluble |
| 115 | P | A | -0.8737 | Soluble |
| 116 | P | A | 0.0000 | Buried |
| 117 | T | A | -0.8065 | Soluble |
| 118 | F | A | 0.0000 | Buried |
| 119 | G | A | -1.5069 | Soluble |
| 120 | Q | A | -1.7318 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -0.8988 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | E | A | -1.2253 | Soluble |
| 126 | I | A | 0.0000 | Buried |
| 127 | K | A | -1.9749 | Soluble |
| 128 | R | A | -1.8239 | Soluble |
| 129 | T | A | -0.4157 | Soluble |
| 130 | V | A | 0.6501 | Aggregation-prone |
| 131 | A | A | 0.0578 | Aggregation-prone |
| 132 | A | A | 0.1980 | Aggregation-prone |
| 133 | P | A | 0.1099 | Aggregation-prone |
| 134 | S | A | -0.0884 | Soluble |
| 135 | V | A | 0.1772 | Aggregation-prone |
| 136 | F | A | 0.0000 | Buried |
| 137 | I | A | 0.0000 | Buried |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.3680 | Soluble |
| 140 | P | A | -0.9837 | Soluble |
| 141 | S | A | -1.6480 | Soluble |
| 142 | D | A | -3.0132 | Soluble |
| 143 | E | A | -3.3042 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.1335 | Soluble |
| 146 | K | A | -2.9835 | Soluble |
| 147 | S | A | -1.9534 | Soluble |
| 148 | G | A | -1.3634 | Soluble |
| 149 | T | A | -0.9462 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | -0.1991 | Soluble |
| 158 | N | A | -0.5880 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | -1.0213 | Soluble |
| 161 | P | A | -1.6828 | Soluble |
| 162 | R | A | -2.9697 | Soluble |
| 163 | E | A | -3.3484 | Soluble |
| 164 | A | A | -2.4134 | Soluble |
| 165 | K | A | -2.6300 | Soluble |
| 166 | V | A | -1.0646 | Soluble |
| 167 | Q | A | -0.4573 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -1.1695 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -2.7432 | Soluble |
| 172 | N | A | -1.9400 | Soluble |
| 173 | A | A | -0.6532 | Soluble |
| 174 | L | A | 0.6855 | Aggregation-prone |
| 175 | Q | A | -0.1177 | Soluble |
| 176 | S | A | -0.4917 | Soluble |
| 177 | G | A | -0.8546 | Soluble |
| 178 | N | A | -1.1408 | Soluble |
| 179 | S | A | -1.2253 | Soluble |
| 180 | Q | A | -1.4918 | Soluble |
| 181 | E | A | -1.8233 | Soluble |
| 182 | S | A | -0.6916 | Soluble |
| 183 | V | A | -0.5001 | Soluble |
| 184 | T | A | -0.7773 | Soluble |
| 185 | E | A | -1.6136 | Soluble |
| 186 | Q | A | 0.0000 | Buried |
| 187 | D | A | -2.0139 | Soluble |
| 188 | S | A | -2.3095 | Soluble |
| 189 | K | A | -2.8239 | Soluble |
| 190 | D | A | -2.2188 | Soluble |
| 191 | S | A | 0.0000 | Buried |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | -1.1562 | Soluble |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | 0.0000 | Buried |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.3297 | Soluble |
| 201 | L | A | -0.8865 | Soluble |
| 202 | S | A | -1.2476 | Soluble |
| 203 | K | A | -2.3052 | Soluble |
| 204 | A | A | -1.9934 | Soluble |
| 205 | D | A | -3.2183 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -3.9052 | Soluble |
| 208 | K | A | -3.9207 | Soluble |
| 209 | H | A | -3.2714 | Soluble |
| 210 | K | A | -3.1385 | Soluble |
| 211 | V | A | -1.6525 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.6495 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.0483 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.8266 | Soluble |
| 220 | G | A | -0.5889 | Soluble |
| 221 | L | A | -0.0459 | Soluble |
| 222 | S | A | -0.3467 | Soluble |
| 223 | S | A | -0.2276 | Soluble |
| 224 | P | A | -0.2113 | Soluble |
| 225 | V | A | 0.6593 | Aggregation-prone |
| 226 | T | A | -0.1576 | Soluble |
| 227 | K | A | -0.7687 | Soluble |
| 228 | S | A | -0.8566 | Soluble |
| 229 | F | A | -0.9347 | Soluble |
| 230 | N | A | -1.2698 | Soluble |
| 231 | R | A | -1.8139 | Soluble |
| 232 | G | A | -2.0310 | Soluble |
| 233 | E | A | -2.0492 | Soluble |
| 234 | C | A | -0.6707 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7669 | 3.7307 | CSV PDB |
| 4.5 | -0.8171 | 3.7307 | CSV PDB |
| 5.0 | -0.8758 | 3.7307 | CSV PDB |
| 5.5 | -0.9318 | 3.7307 | CSV PDB |
| 6.0 | -0.9725 | 3.7307 | CSV PDB |
| 6.5 | -0.989 | 3.7307 | CSV PDB |
| 7.0 | -0.9818 | 3.7307 | CSV PDB |
| 7.5 | -0.9595 | 3.7307 | CSV PDB |
| 8.0 | -0.9286 | 3.7307 | CSV PDB |
| 8.5 | -0.8908 | 3.7306 | CSV PDB |
| 9.0 | -0.845 | 3.7302 | CSV PDB |