Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARSPNPYYYDSSGYYYPGAFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPGLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHYVFGTGTKVTVLRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
input.pdb
|
| Selected Chain(s) | A (Heavy), D (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.5243 | Soluble |
| 2 | V | A | -1.0663 | Soluble |
| 3 | Q | A | -1.3748 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.4629 | Aggregation-prone |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.5305 | Soluble |
| 8 | G | A | -0.6689 | Soluble |
| 9 | A | A | -0.6975 | Soluble |
| 11 | E | A | -1.0675 | Soluble |
| 12 | V | A | -0.6936 | Soluble |
| 13 | K | A | -1.7425 | Soluble |
| 14 | K | A | -2.7203 | Soluble |
| 15 | P | A | -2.6609 | Soluble |
| 16 | G | A | -2.4178 | Soluble |
| 17 | A | A | -1.8160 | Soluble |
| 18 | S | A | -1.8325 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.8520 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6400 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -0.8566 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.6459 | Soluble |
| 27 | G | A | -1.0098 | Soluble |
| 28 | Y | A | -0.3166 | Soluble |
| 29 | T | A | 0.0102 | Aggregation-prone |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.0266 | Aggregation-prone |
| 36 | G | A | 0.0000 | Buried |
| 37 | Y | A | 0.4209 | Aggregation-prone |
| 38 | Y | A | 0.0000 | Buried |
| 39 | M | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.6443 | Soluble |
| 45 | A | A | -1.0117 | Soluble |
| 46 | P | A | -0.8411 | Soluble |
| 47 | G | A | -1.2268 | Soluble |
| 48 | Q | A | -1.6872 | Soluble |
| 49 | G | A | -1.1026 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.6925 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | N | A | 0.0000 | Buried |
| 58 | P | A | 0.0000 | Buried |
| 59 | N | A | -0.5459 | Soluble |
| 62 | S | A | -0.4420 | Soluble |
| 63 | G | A | -0.7411 | Soluble |
| 64 | G | A | -0.6024 | Soluble |
| 65 | T | A | -0.3679 | Soluble |
| 66 | N | A | -0.8409 | Soluble |
| 67 | Y | A | -1.1441 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | Q | A | -2.6234 | Soluble |
| 70 | K | A | -2.6791 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.3730 | Soluble |
| 74 | G | A | -1.7461 | Soluble |
| 75 | R | A | -1.7154 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.8665 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.5840 | Soluble |
| 80 | R | A | -0.8943 | Soluble |
| 81 | D | A | -0.7533 | Soluble |
| 82 | T | A | -0.1961 | Soluble |
| 83 | S | A | 0.3557 | Aggregation-prone |
| 84 | I | A | 1.1293 | Aggregation-prone |
| 85 | S | A | 0.0536 | Aggregation-prone |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.8321 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.5308 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -1.9141 | Soluble |
| 93 | R | A | -2.8876 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.4899 | Soluble |
| 96 | S | A | -2.4130 | Soluble |
| 97 | D | A | -2.4924 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -1.0819 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.1209 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | P | A | 0.2025 | Aggregation-prone |
| 109 | N | A | 0.0000 | Buried |
| 110 | P | A | 0.4403 | Aggregation-prone |
| 111 | Y | A | 1.1353 | Aggregation-prone |
| 111A | Y | A | 1.1105 | Aggregation-prone |
| 111B | Y | A | 0.6155 | Aggregation-prone |
| 111C | D | A | -0.9773 | Soluble |
| 111D | S | A | -0.2202 | Soluble |
| 112E | S | A | -0.0418 | Soluble |
| 112D | G | A | 0.0776 | Aggregation-prone |
| 112C | Y | A | 1.2600 | Aggregation-prone |
| 112B | Y | A | 0.7207 | Aggregation-prone |
| 112A | Y | A | 0.8626 | Aggregation-prone |
| 112 | P | A | -0.0300 | Soluble |
| 113 | G | A | 0.0000 | Buried |
| 114 | A | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.1577 | Soluble |
| 117 | I | A | 0.0080 | Aggregation-prone |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.1736 | Soluble |
| 121 | G | A | -0.5596 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | M | A | -0.1483 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.4962 | Soluble |
| 128 | S | A | -1.2144 | Soluble |
| 129 | A | A | -0.6231 | Soluble |
| 130 | S | A | -0.7032 | Soluble |
| 131 | T | A | -0.7426 | Soluble |
| 132 | K | A | -1.1667 | Soluble |
| 133 | G | A | -1.3743 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3164 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.4687 | Soluble |
| 138 | P | A | -0.9212 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.8604 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.7253 | Soluble |
| 143 | S | A | -0.7177 | Soluble |
| 144 | K | A | -1.0368 | Soluble |
| 145 | S | A | 0.0000 | Buried |
| 146 | T | A | -0.6799 | Soluble |
| 147 | S | A | -0.7387 | Soluble |
| 148 | G | A | -0.8136 | Soluble |
| 149 | G | A | -0.8650 | Soluble |
| 150 | T | A | -0.6000 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.5976 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.3919 | Soluble |
| 164 | P | A | -0.5269 | Soluble |
| 165 | V | A | -0.5354 | Soluble |
| 166 | T | A | -0.5095 | Soluble |
| 167 | V | A | -0.1696 | Soluble |
| 168 | S | A | -0.3501 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.6922 | Soluble |
| 171 | S | A | -0.6224 | Soluble |
| 172 | G | A | -0.3997 | Soluble |
| 173 | A | A | -0.1537 | Soluble |
| 174 | L | A | 0.0869 | Aggregation-prone |
| 175 | T | A | -0.1211 | Soluble |
| 176 | S | A | -0.1748 | Soluble |
| 177 | G | A | -0.1595 | Soluble |
| 178 | V | A | 0.1640 | Aggregation-prone |
| 179 | H | A | -0.1330 | Soluble |
| 180 | T | A | -0.0038 | Soluble |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3436 | Soluble |
| 183 | A | A | 0.1571 | Aggregation-prone |
| 184 | V | A | 0.3998 | Aggregation-prone |
| 185 | L | A | 0.8128 | Aggregation-prone |
| 186 | Q | A | 0.0555 | Aggregation-prone |
| 187 | S | A | -0.2211 | Soluble |
| 188 | S | A | -0.2876 | Soluble |
| 189 | G | A | -0.0293 | Soluble |
| 190 | L | A | 0.0153 | Aggregation-prone |
| 191 | Y | A | 0.2896 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1505 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5494 | Soluble |
| 201 | S | A | -0.6010 | Soluble |
| 202 | S | A | -0.5739 | Soluble |
| 203 | S | A | -0.6014 | Soluble |
| 204 | L | A | -0.7539 | Soluble |
| 205 | G | A | -0.9522 | Soluble |
| 206 | T | A | -0.6736 | Soluble |
| 207 | Q | A | -1.1200 | Soluble |
| 208 | T | A | -1.0193 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.1446 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4543 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.8346 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.8244 | Soluble |
| 217 | P | A | -1.6455 | Soluble |
| 218 | S | A | -1.7941 | Soluble |
| 219 | N | A | -2.5565 | Soluble |
| 220 | T | A | -2.0657 | Soluble |
| 221 | K | A | -2.6646 | Soluble |
| 222 | V | A | -1.5684 | Soluble |
| 223 | D | A | -2.5017 | Soluble |
| 224 | K | A | -1.9065 | Soluble |
| 225 | K | A | -2.3233 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.4104 | Soluble |
| 228 | P | A | -1.2033 | Soluble |
| 3 | G | D | -0.4822 | Soluble |
| 4 | L | D | 0.0000 | Buried |
| 5 | T | D | -0.4559 | Soluble |
| 6 | Q | D | 0.0000 | Buried |
| 7 | P | D | -0.3808 | Soluble |
| 8 | P | D | -0.6202 | Soluble |
| 9 | S | D | -0.6338 | Soluble |
| 11 | V | D | -0.6126 | Soluble |
| 12 | S | D | -0.4806 | Soluble |
| 13 | V | D | 0.0000 | Buried |
| 14 | A | D | -1.0378 | Soluble |
| 15 | P | D | -1.7999 | Soluble |
| 16 | G | D | -2.3038 | Soluble |
| 17 | Q | D | -2.4304 | Soluble |
| 18 | T | D | -1.9269 | Soluble |
| 19 | A | D | 0.0000 | Buried |
| 20 | R | D | -2.0035 | Soluble |
| 21 | I | D | 0.0000 | Buried |
| 22 | T | D | -0.7240 | Soluble |
| 23 | C | D | 0.0000 | Buried |
| 24 | G | D | -1.1709 | Soluble |
| 25 | G | D | -1.7997 | Soluble |
| 26 | N | D | -2.5514 | Soluble |
| 27 | N | D | -2.8505 | Soluble |
| 28 | I | D | 0.0000 | Buried |
| 29 | G | D | -1.9528 | Soluble |
| 36 | S | D | -1.4806 | Soluble |
| 37 | K | D | -1.5109 | Soluble |
| 38 | S | D | -1.1654 | Soluble |
| 39 | V | D | 0.0000 | Buried |
| 40 | H | D | 0.0000 | Buried |
| 41 | W | D | 0.0000 | Buried |
| 42 | Y | D | 0.0000 | Buried |
| 43 | Q | D | 0.0000 | Buried |
| 44 | Q | D | -0.6561 | Soluble |
| 45 | K | D | -1.3346 | Soluble |
| 46 | P | D | -1.4524 | Soluble |
| 47 | G | D | -1.5427 | Soluble |
| 48 | Q | D | -1.6883 | Soluble |
| 49 | A | D | -0.7910 | Soluble |
| 50 | P | D | 0.0000 | Buried |
| 51 | V | D | 0.9689 | Aggregation-prone |
| 52 | L | D | 0.0000 | Buried |
| 53 | V | D | 0.0000 | Buried |
| 54 | V | D | 0.0000 | Buried |
| 55 | Y | D | -1.3323 | Soluble |
| 56 | D | D | -2.1787 | Soluble |
| 57 | D | D | -1.8649 | Soluble |
| 65 | S | D | -1.7392 | Soluble |
| 66 | D | D | -2.2814 | Soluble |
| 67 | R | D | -1.9946 | Soluble |
| 68 | P | D | -0.7686 | Soluble |
| 69 | S | D | -0.7154 | Soluble |
| 70 | G | D | -0.8035 | Soluble |
| 71 | I | D | -0.6119 | Soluble |
| 72 | P | D | -1.2372 | Soluble |
| 74 | E | D | -2.1254 | Soluble |
| 75 | R | D | -1.5511 | Soluble |
| 76 | F | D | 0.0000 | Buried |
| 77 | S | D | -1.3160 | Soluble |
| 78 | G | D | -1.2052 | Soluble |
| 79 | S | D | -0.9675 | Soluble |
| 80 | N | D | -1.4148 | Soluble |
| 83 | S | D | -1.4044 | Soluble |
| 84 | G | D | -2.0025 | Soluble |
| 85 | N | D | -2.6466 | Soluble |
| 86 | T | D | -1.4864 | Soluble |
| 87 | A | D | 0.0000 | Buried |
| 88 | T | D | -0.7772 | Soluble |
| 89 | L | D | 0.0000 | Buried |
| 90 | T | D | -1.0818 | Soluble |
| 91 | I | D | 0.0000 | Buried |
| 92 | S | D | -2.1025 | Soluble |
| 93 | R | D | -2.6805 | Soluble |
| 94 | V | D | 0.0000 | Buried |
| 95 | E | D | -2.9100 | Soluble |
| 96 | A | D | 0.0000 | Buried |
| 97 | G | D | -1.6337 | Soluble |
| 98 | D | D | 0.0000 | Buried |
| 99 | E | D | 0.0000 | Buried |
| 100 | A | D | 0.0000 | Buried |
| 101 | D | D | -0.9602 | Soluble |
| 102 | Y | D | 0.0000 | Buried |
| 103 | Y | D | 0.0000 | Buried |
| 104 | C | D | 0.0000 | Buried |
| 105 | Q | D | 0.0000 | Buried |
| 106 | V | D | 0.0000 | Buried |
| 107 | W | D | -0.4745 | Soluble |
| 108 | D | D | -1.0503 | Soluble |
| 109 | S | D | -1.0378 | Soluble |
| 110 | S | D | -0.8285 | Soluble |
| 113 | S | D | -1.0974 | Soluble |
| 114 | D | D | -1.5553 | Soluble |
| 115 | H | D | -1.0596 | Soluble |
| 116 | Y | D | 0.0000 | Buried |
| 117 | V | D | -0.1424 | Soluble |
| 118 | F | D | 0.0000 | Buried |
| 119 | G | D | 0.0000 | Buried |
| 120 | T | D | -0.5292 | Soluble |
| 121 | G | D | 0.0000 | Buried |
| 122 | T | D | 0.0000 | Buried |
| 123 | K | D | -1.1491 | Soluble |
| 124 | V | D | 0.0000 | Buried |
| 125 | T | D | -0.5671 | Soluble |
| 126 | V | D | 0.0000 | Buried |
| 127 | L | D | 0.0084 | Aggregation-prone |
| 128 | R | D | -0.1843 | Soluble |
| 129 | T | D | 0.2878 | Aggregation-prone |
| 130 | V | D | 0.5443 | Aggregation-prone |
| 131 | A | D | -0.0511 | Soluble |
| 132 | A | D | -0.1005 | Soluble |
| 133 | P | D | 0.0000 | Buried |
| 134 | S | D | -0.1295 | Soluble |
| 135 | V | D | -0.0588 | Soluble |
| 136 | F | D | 0.0000 | Buried |
| 137 | I | D | 0.0000 | Buried |
| 138 | F | D | 0.0000 | Buried |
| 139 | P | D | -0.8891 | Soluble |
| 140 | P | D | -0.7924 | Soluble |
| 141 | S | D | -1.3157 | Soluble |
| 142 | D | D | -2.5932 | Soluble |
| 143 | E | D | -2.2097 | Soluble |
| 144 | Q | D | 0.0000 | Buried |
| 145 | L | D | -1.7927 | Soluble |
| 146 | K | D | -2.5926 | Soluble |
| 147 | S | D | -1.5731 | Soluble |
| 148 | G | D | -1.2456 | Soluble |
| 149 | T | D | -1.1112 | Soluble |
| 150 | A | D | 0.0000 | Buried |
| 151 | S | D | 0.0000 | Buried |
| 152 | V | D | 0.0000 | Buried |
| 153 | V | D | 0.0000 | Buried |
| 154 | C | D | 0.0000 | Buried |
| 155 | L | D | 0.0000 | Buried |
| 156 | L | D | 0.0000 | Buried |
| 157 | N | D | 0.0000 | Buried |
| 158 | N | D | -0.8242 | Soluble |
| 159 | F | D | 0.0000 | Buried |
| 160 | Y | D | 0.0000 | Buried |
| 161 | P | D | -1.4719 | Soluble |
| 162 | R | D | -3.0890 | Soluble |
| 163 | E | D | -3.2319 | Soluble |
| 164 | A | D | -2.2582 | Soluble |
| 165 | K | D | -2.1985 | Soluble |
| 166 | V | D | -0.8927 | Soluble |
| 167 | Q | D | -0.4608 | Soluble |
| 168 | W | D | 0.0000 | Buried |
| 169 | K | D | -0.4131 | Soluble |
| 170 | V | D | 0.0000 | Buried |
| 171 | D | D | -1.9844 | Soluble |
| 172 | N | D | -1.5063 | Soluble |
| 173 | A | D | -0.2122 | Soluble |
| 174 | L | D | 0.7899 | Aggregation-prone |
| 175 | Q | D | -0.0579 | Soluble |
| 176 | S | D | -0.4458 | Soluble |
| 177 | G | D | -0.8993 | Soluble |
| 178 | N | D | -0.8650 | Soluble |
| 179 | S | D | -1.0408 | Soluble |
| 180 | Q | D | -1.2376 | Soluble |
| 181 | E | D | -1.6227 | Soluble |
| 182 | S | D | -0.8349 | Soluble |
| 183 | V | D | -0.7247 | Soluble |
| 184 | T | D | -0.9898 | Soluble |
| 185 | E | D | -1.8457 | Soluble |
| 186 | Q | D | 0.0000 | Buried |
| 187 | D | D | -1.9135 | Soluble |
| 188 | S | D | -2.1062 | Soluble |
| 189 | K | D | -2.5947 | Soluble |
| 190 | D | D | -1.9746 | Soluble |
| 191 | S | D | 0.0000 | Buried |
| 192 | T | D | 0.0000 | Buried |
| 193 | Y | D | 0.0000 | Buried |
| 194 | S | D | 0.0000 | Buried |
| 195 | L | D | 0.0000 | Buried |
| 196 | S | D | 0.0000 | Buried |
| 197 | S | D | 0.0000 | Buried |
| 198 | T | D | -0.5927 | Soluble |
| 199 | L | D | 0.0000 | Buried |
| 200 | T | D | -0.4594 | Soluble |
| 201 | L | D | -0.7978 | Soluble |
| 202 | S | D | -1.1613 | Soluble |
| 203 | K | D | -2.1196 | Soluble |
| 204 | A | D | -2.0929 | Soluble |
| 205 | D | D | -3.0210 | Soluble |
| 206 | Y | D | 0.0000 | Buried |
| 207 | E | D | -3.9493 | Soluble |
| 208 | K | D | -3.7471 | Soluble |
| 209 | H | D | -3.3340 | Soluble |
| 210 | K | D | -3.6840 | Soluble |
| 211 | V | D | -2.1575 | Soluble |
| 212 | Y | D | 0.0000 | Buried |
| 213 | A | D | 0.0000 | Buried |
| 214 | C | D | 0.0000 | Buried |
| 215 | E | D | -0.4620 | Soluble |
| 216 | V | D | 0.0000 | Buried |
| 217 | T | D | -1.0870 | Soluble |
| 218 | H | D | 0.0000 | Buried |
| 219 | Q | D | -1.7568 | Soluble |
| 220 | G | D | -0.4518 | Soluble |
| 221 | L | D | -0.2432 | Soluble |
| 222 | S | D | -0.4654 | Soluble |
| 223 | S | D | -0.3953 | Soluble |
| 224 | P | D | -0.4216 | Soluble |
| 225 | V | D | 0.4099 | Aggregation-prone |
| 226 | T | D | -0.1061 | Soluble |
| 227 | K | D | -0.4321 | Soluble |
| 228 | S | D | -0.9434 | Soluble |
| 229 | F | D | 0.0000 | Buried |
| 230 | N | D | -2.7365 | Soluble |
| 231 | R | D | -3.2197 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6478 | 2.9149 | CSV PDB |
| 4.5 | -0.6915 | 2.8823 | CSV PDB |
| 5.0 | -0.7413 | 2.8381 | CSV PDB |
| 5.5 | -0.7882 | 2.788 | CSV PDB |
| 6.0 | -0.823 | 2.7356 | CSV PDB |
| 6.5 | -0.8388 | 2.6826 | CSV PDB |
| 7.0 | -0.836 | 2.6293 | CSV PDB |
| 7.5 | -0.8211 | 2.5761 | CSV PDB |
| 8.0 | -0.7992 | 2.5233 | CSV PDB |
| 8.5 | -0.771 | 2.4717 | CSV PDB |
| 9.0 | -0.7355 | 2.4225 | CSV PDB |