Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.4129 | Soluble |
| 2 | V | A | -0.9791 | Soluble |
| 3 | Q | A | -1.7277 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.6305 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.8380 | Soluble |
| 8 | G | A | -0.7000 | Soluble |
| 9 | A | A | -0.1476 | Soluble |
| 11 | E | A | -0.5268 | Soluble |
| 12 | V | A | 0.3316 | Aggregation-prone |
| 13 | K | A | -1.2242 | Soluble |
| 14 | K | A | -2.3781 | Soluble |
| 15 | P | A | -2.3284 | Soluble |
| 16 | G | A | -2.3167 | Soluble |
| 17 | A | A | -1.9788 | Soluble |
| 18 | S | A | -2.3418 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.0470 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6431 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.7895 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0891 | Soluble |
| 27 | G | A | -0.8397 | Soluble |
| 28 | Y | A | -0.3974 | Soluble |
| 29 | P | A | -0.3051 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.2735 | Aggregation-prone |
| 36 | S | A | 0.3578 | Aggregation-prone |
| 37 | Y | A | 0.4528 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.5927 | Soluble |
| 45 | A | A | -0.9604 | Soluble |
| 46 | P | A | -0.7991 | Soluble |
| 47 | G | A | -1.2261 | Soluble |
| 48 | Q | A | -1.7464 | Soluble |
| 49 | G | A | -1.1093 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.6149 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.7717 | Aggregation-prone |
| 62 | N | A | -0.7690 | Soluble |
| 63 | G | A | -1.2192 | Soluble |
| 64 | N | A | -1.6677 | Soluble |
| 65 | T | A | -1.1352 | Soluble |
| 66 | N | A | -1.1200 | Soluble |
| 67 | Y | A | -1.1274 | Soluble |
| 68 | A | A | -1.5937 | Soluble |
| 69 | Q | A | -2.5590 | Soluble |
| 70 | K | A | -2.7209 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.4623 | Soluble |
| 74 | G | A | -1.8573 | Soluble |
| 75 | R | A | -2.0243 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.7384 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.3730 | Soluble |
| 80 | T | A | -0.4899 | Soluble |
| 81 | D | A | -1.0912 | Soluble |
| 82 | T | A | -0.4565 | Soluble |
| 83 | S | A | -0.5491 | Soluble |
| 84 | T | A | -0.7985 | Soluble |
| 85 | T | A | -0.9473 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.3490 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.4204 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -3.3325 | Soluble |
| 93 | R | A | -3.4881 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.6133 | Soluble |
| 96 | S | A | -2.3132 | Soluble |
| 97 | D | A | -2.4794 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7339 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2759 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.2636 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 0.8018 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.4307 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.6020 | Aggregation-prone |
| 111C | F | A | 1.7775 | Aggregation-prone |
| 112D | G | A | -0.3477 | Soluble |
| 112C | E | A | -1.3898 | Soluble |
| 112B | S | A | -0.7769 | Soluble |
| 112A | L | A | 0.4672 | Aggregation-prone |
| 112 | I | A | 1.6986 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.6288 | Soluble |
| 117 | N | A | -0.7929 | Soluble |
| 118 | W | A | -0.8174 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4791 | Soluble |
| 121 | G | A | -0.6739 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.2451 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.1319 | Soluble |
| 128 | S | A | -1.1043 | Soluble |
| 129 | A | A | -0.7846 | Soluble |
| 130 | S | A | -0.7964 | Soluble |
| 131 | T | A | -0.9233 | Soluble |
| 132 | K | A | -1.6353 | Soluble |
| 133 | G | A | -1.7073 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.7342 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.0678 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.2327 | Soluble |
| 141 | P | A | -0.9832 | Soluble |
| 142 | S | A | -1.1027 | Soluble |
| 143 | S | A | -1.5137 | Soluble |
| 144 | K | A | -1.9964 | Soluble |
| 145 | S | A | -1.3908 | Soluble |
| 146 | T | A | -0.9007 | Soluble |
| 147 | S | A | -0.6629 | Soluble |
| 148 | G | A | -0.9621 | Soluble |
| 149 | G | A | -0.8857 | Soluble |
| 150 | T | A | -0.6038 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | -0.8364 | Soluble |
| 159 | D | A | -1.1729 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.3003 | Soluble |
| 164 | P | A | -0.7688 | Soluble |
| 165 | V | A | -0.5710 | Soluble |
| 166 | T | A | -0.5200 | Soluble |
| 167 | V | A | -0.1713 | Soluble |
| 168 | S | A | -0.4924 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.6054 | Soluble |
| 171 | S | A | -0.6443 | Soluble |
| 172 | G | A | -0.5015 | Soluble |
| 173 | A | A | -0.2119 | Soluble |
| 174 | L | A | -0.0301 | Soluble |
| 175 | T | A | -0.1691 | Soluble |
| 176 | S | A | -0.2682 | Soluble |
| 177 | G | A | -0.3485 | Soluble |
| 178 | V | A | 0.1055 | Aggregation-prone |
| 179 | H | A | -0.5392 | Soluble |
| 180 | T | A | -0.0429 | Soluble |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.4105 | Soluble |
| 183 | A | A | 0.1231 | Aggregation-prone |
| 184 | V | A | 0.4518 | Aggregation-prone |
| 185 | L | A | 1.1255 | Aggregation-prone |
| 186 | Q | A | 0.1759 | Aggregation-prone |
| 187 | S | A | -0.1166 | Soluble |
| 188 | S | A | -0.3008 | Soluble |
| 189 | G | A | -0.1711 | Soluble |
| 190 | L | A | 0.0000 | Buried |
| 191 | Y | A | 0.1540 | Aggregation-prone |
| 192 | S | A | -0.0259 | Soluble |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.2417 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.6890 | Soluble |
| 201 | S | A | -0.9326 | Soluble |
| 202 | S | A | -0.7209 | Soluble |
| 203 | S | A | -0.6746 | Soluble |
| 204 | L | A | -0.7808 | Soluble |
| 205 | G | A | -1.0880 | Soluble |
| 206 | T | A | -0.8318 | Soluble |
| 207 | Q | A | -1.5094 | Soluble |
| 208 | T | A | -1.2132 | Soluble |
| 209 | Y | A | -0.8456 | Soluble |
| 210 | I | A | -1.3848 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.7330 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -2.4184 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7961 | Soluble |
| 217 | P | A | -1.7480 | Soluble |
| 218 | S | A | -1.9716 | Soluble |
| 219 | N | A | -2.6319 | Soluble |
| 220 | T | A | -2.4247 | Soluble |
| 221 | K | A | -2.9541 | Soluble |
| 222 | V | A | -1.8405 | Soluble |
| 223 | D | A | -2.8746 | Soluble |
| 224 | K | A | -2.3637 | Soluble |
| 225 | K | A | -2.5756 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.9278 | Soluble |
| 228 | P | A | -2.0767 | Soluble |
| 229 | K | A | -2.5868 | Soluble |
| 1 | E | B | -1.7290 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.7450 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.4959 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.9187 | Soluble |
| 8 | P | B | -0.6690 | Soluble |
| 9 | G | B | -0.9074 | Soluble |
| 10 | T | B | -0.6451 | Soluble |
| 11 | L | B | -0.3895 | Soluble |
| 12 | S | B | -0.6144 | Soluble |
| 13 | L | B | -1.1361 | Soluble |
| 14 | S | B | -1.7917 | Soluble |
| 15 | P | B | -2.0562 | Soluble |
| 16 | G | B | -2.3913 | Soluble |
| 17 | E | B | -3.4599 | Soluble |
| 18 | R | B | -3.4466 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.5009 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.7868 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.1103 | Soluble |
| 25 | A | B | -1.0903 | Soluble |
| 26 | S | B | -1.0494 | Soluble |
| 27 | Q | B | -1.6496 | Soluble |
| 28 | T | B | -1.2405 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6655 | Soluble |
| 36 | S | B | -0.2858 | Soluble |
| 37 | T | B | 0.2014 | Aggregation-prone |
| 38 | S | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.3242 | Soluble |
| 46 | P | B | -1.2409 | Soluble |
| 47 | G | B | -1.4362 | Soluble |
| 48 | Q | B | -1.9990 | Soluble |
| 49 | A | B | -1.3133 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.1711 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.2732 | Aggregation-prone |
| 56 | G | B | 0.2251 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.6981 | Soluble |
| 66 | S | B | -0.6769 | Soluble |
| 67 | R | B | -1.8398 | Soluble |
| 68 | A | B | -0.9604 | Soluble |
| 69 | T | B | -0.6948 | Soluble |
| 70 | G | B | -0.9271 | Soluble |
| 71 | I | B | 0.0000 | Buried |
| 72 | P | B | -1.3907 | Soluble |
| 74 | D | B | -2.2820 | Soluble |
| 75 | R | B | -2.1194 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -1.0469 | Soluble |
| 78 | G | B | -0.5778 | Soluble |
| 79 | S | B | -0.6243 | Soluble |
| 80 | G | B | -0.7259 | Soluble |
| 83 | S | B | -0.7166 | Soluble |
| 84 | G | B | -0.9638 | Soluble |
| 85 | T | B | -1.4315 | Soluble |
| 86 | D | B | -1.7018 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.6587 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8254 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.5019 | Soluble |
| 93 | R | B | -3.4665 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.2209 | Soluble |
| 96 | P | B | -1.5975 | Soluble |
| 97 | E | B | -2.0108 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.7199 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.4954 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | -0.6465 | Soluble |
| 108 | D | B | -1.5347 | Soluble |
| 114 | T | B | -1.1658 | Soluble |
| 115 | S | B | -1.0907 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.0955 | Soluble |
| 118 | F | B | 0.2312 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.6112 | Soluble |
| 121 | G | B | -0.8195 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.0905 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -0.7190 | Soluble |
| 126 | I | B | -0.8020 | Soluble |
| 127 | K | B | -1.5403 | Soluble |
| 128 | R | B | -1.1139 | Soluble |
| 129 | T | B | 0.0808 | Aggregation-prone |
| 130 | V | B | 1.1438 | Aggregation-prone |
| 131 | A | B | 0.4693 | Aggregation-prone |
| 132 | A | B | 0.0705 | Aggregation-prone |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1599 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.1507 | Aggregation-prone |
| 137 | I | B | 0.1798 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.7668 | Soluble |
| 140 | P | B | -0.6623 | Soluble |
| 141 | S | B | -1.6298 | Soluble |
| 142 | D | B | -2.8516 | Soluble |
| 143 | E | B | -2.5990 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.7138 | Soluble |
| 146 | K | B | -2.5816 | Soluble |
| 147 | S | B | -1.6823 | Soluble |
| 148 | G | B | -1.1819 | Soluble |
| 149 | T | B | -0.8666 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | -0.0860 | Soluble |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | -0.4635 | Soluble |
| 158 | N | B | -0.7812 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | -0.6417 | Soluble |
| 161 | P | B | 0.0000 | Buried |
| 162 | R | B | -2.8070 | Soluble |
| 163 | E | B | -3.1908 | Soluble |
| 164 | A | B | -2.3340 | Soluble |
| 165 | K | B | -2.2670 | Soluble |
| 166 | V | B | -1.1043 | Soluble |
| 167 | Q | B | -0.5683 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5173 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.4302 | Soluble |
| 172 | N | B | -1.3437 | Soluble |
| 173 | A | B | -0.1251 | Soluble |
| 174 | L | B | 0.6026 | Aggregation-prone |
| 175 | Q | B | 0.0203 | Aggregation-prone |
| 176 | S | B | -0.4929 | Soluble |
| 177 | G | B | -0.8663 | Soluble |
| 178 | N | B | -0.7885 | Soluble |
| 179 | S | B | -1.1114 | Soluble |
| 180 | Q | B | -1.3091 | Soluble |
| 181 | E | B | -1.9066 | Soluble |
| 182 | S | B | -0.8130 | Soluble |
| 183 | V | B | -0.8198 | Soluble |
| 184 | T | B | -1.0832 | Soluble |
| 185 | E | B | -2.3098 | Soluble |
| 186 | Q | B | -2.2509 | Soluble |
| 187 | D | B | -2.6198 | Soluble |
| 188 | S | B | -2.0311 | Soluble |
| 189 | K | B | -2.4487 | Soluble |
| 190 | D | B | -1.8902 | Soluble |
| 191 | S | B | -1.9084 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6149 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.2285 | Soluble |
| 201 | L | B | -0.3893 | Soluble |
| 202 | S | B | -1.0328 | Soluble |
| 203 | K | B | -2.0926 | Soluble |
| 204 | A | B | -1.6925 | Soluble |
| 205 | D | B | -2.4052 | Soluble |
| 206 | Y | B | -2.6087 | Soluble |
| 207 | E | B | -3.8186 | Soluble |
| 208 | K | B | -3.5090 | Soluble |
| 209 | H | B | 0.0000 | Buried |
| 210 | K | B | -3.1061 | Soluble |
| 211 | V | B | -1.3447 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7017 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.0974 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.2533 | Soluble |
| 220 | G | B | -0.2455 | Soluble |
| 221 | L | B | -0.2103 | Soluble |
| 222 | S | B | -0.5097 | Soluble |
| 223 | S | B | -0.4106 | Soluble |
| 224 | P | B | -0.3594 | Soluble |
| 225 | V | B | 0.1375 | Aggregation-prone |
| 226 | T | B | -0.3783 | Soluble |
| 227 | K | B | -0.5807 | Soluble |
| 228 | S | B | -0.6324 | Soluble |
| 229 | F | B | -0.9769 | Soluble |
| 230 | N | B | -2.2131 | Soluble |
| 231 | R | B | -3.2881 | Soluble |
| 232 | G | B | -1.9513 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7756 | 5.3642 | CSV PDB |
| 4.5 | -0.8167 | 5.3033 | CSV PDB |
| 5.0 | -0.8651 | 5.2031 | CSV PDB |
| 5.5 | -0.9114 | 5.0777 | CSV PDB |
| 6.0 | -0.9444 | 4.9478 | CSV PDB |
| 6.5 | -0.9548 | 4.8812 | CSV PDB |
| 7.0 | -0.9413 | 4.8434 | CSV PDB |
| 7.5 | -0.9107 | 4.8239 | CSV PDB |
| 8.0 | -0.8701 | 4.8162 | CSV PDB |
| 8.5 | -0.8221 | 4.8134 | CSV PDB |
| 9.0 | -0.7679 | 4.8119 | CSV PDB |