Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAVSGYSITSGYSWNWIRQAPGKGLEWVASITYDGSTNYNPSVKGRITISRDDSKNTFYLQMNSLRAEDTAVYYCARGSHYFGHWHFAVWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKDIQLTQSPSSLSASVGDRVTITCRASQSVDYDGDSYMNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSHEDPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.0853 | Soluble |
| 2 | V | A | -1.3940 | Soluble |
| 3 | Q | A | -1.3202 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 1.1930 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.1917 | Soluble |
| 8 | G | A | -0.9330 | Soluble |
| 9 | G | A | -0.6138 | Soluble |
| 11 | G | A | -0.2629 | Soluble |
| 12 | L | A | -0.0467 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.6819 | Soluble |
| 15 | P | A | -1.6616 | Soluble |
| 16 | G | A | -1.5700 | Soluble |
| 17 | G | A | -1.3946 | Soluble |
| 18 | S | A | -1.7913 | Soluble |
| 19 | L | A | 0.0000 | Buried |
| 20 | R | A | -2.3855 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.5314 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.0697 | Soluble |
| 25 | V | A | 0.0000 | Buried |
| 26 | S | A | -0.9177 | Soluble |
| 27 | G | A | -1.1815 | Soluble |
| 28 | Y | A | -0.4292 | Soluble |
| 29 | S | A | -0.5237 | Soluble |
| 30 | I | A | 0.0000 | Buried |
| 31 | T | A | -0.7494 | Soluble |
| 35 | S | A | -0.1767 | Soluble |
| 36 | G | A | 0.0000 | Buried |
| 37 | Y | A | 0.1455 | Aggregation-prone |
| 38 | S | A | 0.0000 | Buried |
| 39 | W | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | I | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.7010 | Soluble |
| 45 | A | A | -1.1501 | Soluble |
| 46 | P | A | -1.1989 | Soluble |
| 47 | G | A | -1.4785 | Soluble |
| 48 | K | A | -2.3876 | Soluble |
| 49 | G | A | -1.6591 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.8606 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | S | A | -0.3599 | Soluble |
| 56 | I | A | 0.0000 | Buried |
| 57 | T | A | -0.4021 | Soluble |
| 58 | Y | A | -0.2247 | Soluble |
| 59 | D | A | -1.5578 | Soluble |
| 63 | G | A | -1.1148 | Soluble |
| 64 | S | A | -0.8534 | Soluble |
| 65 | T | A | -0.7166 | Soluble |
| 66 | N | A | -1.3535 | Soluble |
| 67 | Y | A | -1.0814 | Soluble |
| 68 | N | A | 0.0000 | Buried |
| 69 | P | A | -1.5320 | Soluble |
| 70 | S | A | -0.9360 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.2486 | Soluble |
| 74 | G | A | -1.6641 | Soluble |
| 75 | R | A | -1.6535 | Soluble |
| 76 | I | A | 0.0000 | Buried |
| 77 | T | A | -1.0818 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.7944 | Soluble |
| 80 | R | A | -1.5936 | Soluble |
| 81 | D | A | -2.4108 | Soluble |
| 82 | D | A | -2.9902 | Soluble |
| 83 | S | A | -2.2432 | Soluble |
| 84 | K | A | -2.7837 | Soluble |
| 85 | N | A | -2.1092 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | F | A | 0.0000 | Buried |
| 88 | Y | A | 0.0000 | Buried |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.6284 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -2.1207 | Soluble |
| 93 | S | A | -1.5862 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.8560 | Soluble |
| 96 | A | A | -1.9404 | Soluble |
| 97 | E | A | -2.4027 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.8345 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2696 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.1659 | Soluble |
| 107 | G | A | 0.0000 | Buried |
| 108 | S | A | -0.2861 | Soluble |
| 109 | H | A | -0.4537 | Soluble |
| 110 | Y | A | 0.4976 | Aggregation-prone |
| 111 | F | A | 1.3610 | Aggregation-prone |
| 112A | G | A | 0.1591 | Aggregation-prone |
| 112 | H | A | -0.1197 | Soluble |
| 113 | W | A | -0.0017 | Soluble |
| 114 | H | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | A | A | -0.2458 | Soluble |
| 117 | V | A | -0.2805 | Soluble |
| 118 | W | A | -0.3926 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3192 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | 0.0516 | Aggregation-prone |
| 123 | L | A | 0.0971 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.7991 | Soluble |
| 128 | S | A | -0.6712 | Soluble |
| 129 | A | A | -0.4923 | Soluble |
| 130 | S | A | -0.5976 | Soluble |
| 131 | T | A | -0.8255 | Soluble |
| 132 | K | A | -1.4305 | Soluble |
| 133 | G | A | -1.5461 | Soluble |
| 134 | P | A | -0.6864 | Soluble |
| 135 | S | A | -0.3350 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.0192 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.0797 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -1.3230 | Soluble |
| 143 | S | A | -1.4357 | Soluble |
| 144 | K | A | -2.0622 | Soluble |
| 145 | S | A | -1.1666 | Soluble |
| 146 | T | A | -1.0849 | Soluble |
| 147 | S | A | -0.9720 | Soluble |
| 148 | G | A | -1.0533 | Soluble |
| 149 | G | A | -1.1565 | Soluble |
| 150 | T | A | -0.8404 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.5036 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.4021 | Soluble |
| 164 | P | A | -0.6439 | Soluble |
| 165 | V | A | -0.6761 | Soluble |
| 166 | T | A | -0.5963 | Soluble |
| 167 | V | A | -0.2104 | Soluble |
| 168 | S | A | -0.3769 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.6277 | Soluble |
| 171 | S | A | -0.6283 | Soluble |
| 172 | G | A | -0.4637 | Soluble |
| 173 | A | A | -0.2139 | Soluble |
| 174 | L | A | 0.0515 | Aggregation-prone |
| 175 | T | A | -0.1615 | Soluble |
| 176 | S | A | -0.1777 | Soluble |
| 177 | G | A | -0.1633 | Soluble |
| 178 | V | A | 0.1589 | Aggregation-prone |
| 179 | H | A | -0.2118 | Soluble |
| 180 | T | A | -0.0139 | Soluble |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3189 | Soluble |
| 183 | A | A | 0.2483 | Aggregation-prone |
| 184 | V | A | 0.5614 | Aggregation-prone |
| 185 | L | A | 1.1187 | Aggregation-prone |
| 186 | Q | A | 0.2496 | Aggregation-prone |
| 187 | S | A | -0.1640 | Soluble |
| 188 | S | A | -0.2625 | Soluble |
| 189 | G | A | -0.0316 | Soluble |
| 190 | L | A | 0.0525 | Aggregation-prone |
| 191 | Y | A | 0.4150 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1360 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.6141 | Soluble |
| 201 | S | A | -0.9374 | Soluble |
| 202 | S | A | -0.5929 | Soluble |
| 203 | S | A | -0.5754 | Soluble |
| 204 | L | A | -0.8107 | Soluble |
| 205 | G | A | -0.9315 | Soluble |
| 206 | T | A | -0.6582 | Soluble |
| 207 | Q | A | -1.0573 | Soluble |
| 208 | T | A | -0.8714 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -0.9290 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.3962 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -2.0292 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7986 | Soluble |
| 217 | P | A | -1.5965 | Soluble |
| 218 | S | A | -1.8991 | Soluble |
| 219 | N | A | -2.6423 | Soluble |
| 220 | T | A | -2.1680 | Soluble |
| 221 | K | A | -2.6973 | Soluble |
| 222 | V | A | -1.5476 | Soluble |
| 223 | D | A | -2.3904 | Soluble |
| 224 | K | A | -1.7664 | Soluble |
| 225 | K | A | -1.8502 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.6428 | Soluble |
| 228 | P | A | -1.9713 | Soluble |
| 229 | K | A | -2.4829 | Soluble |
| 1 | D | B | -2.9477 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | Q | B | -2.1916 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -1.0000 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.7746 | Soluble |
| 8 | P | B | -0.5636 | Soluble |
| 9 | S | B | -0.9045 | Soluble |
| 10 | S | B | -0.9745 | Soluble |
| 11 | L | B | -0.7017 | Soluble |
| 12 | S | B | -0.9653 | Soluble |
| 13 | A | B | -1.2225 | Soluble |
| 14 | S | B | -1.1571 | Soluble |
| 15 | V | B | -0.2491 | Soluble |
| 16 | G | B | -1.0835 | Soluble |
| 17 | D | B | -2.3990 | Soluble |
| 18 | R | B | -2.6889 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.7205 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.6801 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -1.8725 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -1.7928 | Soluble |
| 27 | Q | B | -2.3575 | Soluble |
| 28 | S | B | -1.4735 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | D | B | -1.3657 | Soluble |
| 31 | Y | B | -0.6582 | Soluble |
| 34 | D | B | -1.6917 | Soluble |
| 35 | G | B | -1.4397 | Soluble |
| 36 | D | B | -0.8102 | Soluble |
| 37 | S | B | 0.0000 | Buried |
| 38 | Y | B | 0.0000 | Buried |
| 39 | M | B | 0.0000 | Buried |
| 40 | N | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.3248 | Soluble |
| 45 | K | B | -1.8473 | Soluble |
| 46 | P | B | -1.5302 | Soluble |
| 47 | G | B | -1.8285 | Soluble |
| 48 | K | B | -2.5822 | Soluble |
| 49 | A | B | -1.6334 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.4389 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.4738 | Aggregation-prone |
| 56 | A | B | 0.0000 | Buried |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | 0.0488 | Aggregation-prone |
| 66 | Y | B | 0.6932 | Aggregation-prone |
| 67 | L | B | 0.6254 | Aggregation-prone |
| 68 | E | B | -0.1475 | Soluble |
| 69 | S | B | -0.3378 | Soluble |
| 70 | G | B | -0.5154 | Soluble |
| 71 | V | B | -0.3551 | Soluble |
| 72 | P | B | -0.3314 | Soluble |
| 74 | S | B | -0.4351 | Soluble |
| 75 | R | B | -0.7837 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.2150 | Soluble |
| 78 | G | B | -0.1490 | Soluble |
| 79 | S | B | -0.6426 | Soluble |
| 80 | G | B | -1.0546 | Soluble |
| 83 | S | B | -1.2348 | Soluble |
| 84 | G | B | -1.2295 | Soluble |
| 85 | T | B | -1.6184 | Soluble |
| 86 | D | B | -1.9983 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7009 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6340 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.4677 | Soluble |
| 93 | S | B | -1.3581 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.0600 | Soluble |
| 96 | P | B | -1.5616 | Soluble |
| 97 | E | B | -1.8121 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -1.3979 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | 0.0000 | Buried |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | S | B | 0.0000 | Buried |
| 108 | H | B | -1.6467 | Soluble |
| 109 | E | B | -3.1093 | Soluble |
| 114 | D | B | -3.0839 | Soluble |
| 115 | P | B | 0.0000 | Buried |
| 116 | Y | B | -1.3909 | Soluble |
| 117 | T | B | -1.2917 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.8613 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.8606 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.6120 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.2997 | Soluble |
| 128 | R | B | -0.9072 | Soluble |
| 129 | T | B | -0.0362 | Soluble |
| 130 | V | B | 0.5323 | Aggregation-prone |
| 131 | A | B | 0.2121 | Aggregation-prone |
| 132 | A | B | -0.0635 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2283 | Soluble |
| 135 | V | B | -0.1099 | Soluble |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | -0.0151 | Soluble |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.7025 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.5751 | Soluble |
| 142 | D | B | -2.8305 | Soluble |
| 143 | E | B | -2.8031 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.3009 | Soluble |
| 146 | K | B | -2.7828 | Soluble |
| 147 | S | B | -1.8056 | Soluble |
| 148 | G | B | -1.2946 | Soluble |
| 149 | T | B | -0.8793 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.9144 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.7247 | Soluble |
| 162 | R | B | -2.9422 | Soluble |
| 163 | E | B | -3.1658 | Soluble |
| 164 | A | B | -2.1881 | Soluble |
| 165 | K | B | -1.9120 | Soluble |
| 166 | V | B | -1.0170 | Soluble |
| 167 | Q | B | -0.5309 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5450 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.6985 | Soluble |
| 172 | N | B | -1.3056 | Soluble |
| 173 | A | B | -0.2129 | Soluble |
| 174 | L | B | 0.6860 | Aggregation-prone |
| 175 | Q | B | -0.0847 | Soluble |
| 176 | S | B | -0.4670 | Soluble |
| 177 | G | B | -0.8349 | Soluble |
| 178 | N | B | -0.7177 | Soluble |
| 179 | S | B | -1.0438 | Soluble |
| 180 | Q | B | -1.3360 | Soluble |
| 181 | E | B | -1.9119 | Soluble |
| 182 | S | B | -0.9794 | Soluble |
| 183 | V | B | -0.9968 | Soluble |
| 184 | T | B | -1.1607 | Soluble |
| 185 | E | B | -2.2041 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.2124 | Soluble |
| 188 | S | B | -2.2170 | Soluble |
| 189 | K | B | -2.5773 | Soluble |
| 190 | D | B | -1.9266 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.6186 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.2949 | Soluble |
| 201 | L | B | -0.6636 | Soluble |
| 202 | S | B | -1.3018 | Soluble |
| 203 | K | B | -2.2568 | Soluble |
| 204 | A | B | -1.9620 | Soluble |
| 205 | D | B | -2.6943 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.5968 | Soluble |
| 208 | K | B | -3.6143 | Soluble |
| 209 | H | B | -3.0514 | Soluble |
| 210 | K | B | -3.1199 | Soluble |
| 211 | V | B | -1.5200 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7291 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.0805 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6934 | Soluble |
| 220 | G | B | -0.3931 | Soluble |
| 221 | L | B | -0.2067 | Soluble |
| 222 | S | B | -0.4450 | Soluble |
| 223 | S | B | -0.4040 | Soluble |
| 224 | P | B | -0.5052 | Soluble |
| 225 | V | B | -0.1009 | Soluble |
| 226 | T | B | -0.6002 | Soluble |
| 227 | K | B | -0.9034 | Soluble |
| 228 | S | B | -0.7062 | Soluble |
| 229 | F | B | -1.0361 | Soluble |
| 230 | N | B | -2.0605 | Soluble |
| 231 | R | B | -2.6354 | Soluble |
| 232 | G | B | -2.1959 | Soluble |
| 233 | E | B | -2.5686 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7742 | 3.6838 | CSV PDB |
| 4.5 | -0.8233 | 3.6346 | CSV PDB |
| 5.0 | -0.8809 | 3.5778 | CSV PDB |
| 5.5 | -0.9364 | 3.5251 | CSV PDB |
| 6.0 | -0.9776 | 3.4893 | CSV PDB |
| 6.5 | -0.995 | 3.4785 | CSV PDB |
| 7.0 | -0.9883 | 3.4801 | CSV PDB |
| 7.5 | -0.9655 | 3.467 | CSV PDB |
| 8.0 | -0.9335 | 3.43 | CSV PDB |
| 8.5 | -0.8944 | 3.3812 | CSV PDB |
| 9.0 | -0.8479 | 3.3367 | CSV PDB |