Calculation Parameters
| Chain Sequence(s) |
QVQLVESGGGLVQPGGSLRLSCAASGFTFSYYDIQWVRQAPGKGLEWVSSISPSGQSTYYRREVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARRTGREEGGWIFDYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYTCNVDHKPSNTKVDKRVESEIVLTQSPATLSVSPGERATLSCRASRSVRRELAWYQQKPGQAPELLIYGASTRETGIPARFSGSGSGTDFTLTINSLEAEDAATYYCQQYRDPPGTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.5714 | Soluble |
| 2 | V | A | -1.0209 | Soluble |
| 3 | Q | A | -1.4622 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.2459 | Soluble |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.6353 | Soluble |
| 8 | G | A | -0.8386 | Soluble |
| 9 | G | A | -0.7602 | Soluble |
| 11 | G | A | -0.3868 | Soluble |
| 12 | L | A | -0.1757 | Soluble |
| 13 | V | A | -0.4554 | Soluble |
| 14 | Q | A | -1.5322 | Soluble |
| 15 | P | A | -1.6962 | Soluble |
| 16 | G | A | -1.5515 | Soluble |
| 17 | G | A | -1.1737 | Soluble |
| 18 | S | A | -1.5065 | Soluble |
| 19 | L | A | -1.2752 | Soluble |
| 20 | R | A | -2.3342 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.6374 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.4613 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.1322 | Soluble |
| 27 | G | A | -1.1522 | Soluble |
| 28 | F | A | -0.3191 | Soluble |
| 29 | T | A | 0.1182 | Aggregation-prone |
| 30 | F | A | 0.0000 | Buried |
| 35 | S | A | -0.0099 | Soluble |
| 36 | Y | A | 1.1092 | Aggregation-prone |
| 37 | Y | A | 0.3044 | Aggregation-prone |
| 38 | D | A | -0.0202 | Soluble |
| 39 | I | A | 0.0000 | Buried |
| 40 | Q | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.6099 | Soluble |
| 45 | A | A | 0.0000 | Buried |
| 46 | P | A | -1.1140 | Soluble |
| 47 | G | A | -1.5069 | Soluble |
| 48 | K | A | -2.2230 | Soluble |
| 49 | G | A | -1.3155 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.7094 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | S | A | 0.0000 | Buried |
| 55 | S | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | -0.2881 | Soluble |
| 58 | P | A | -0.2474 | Soluble |
| 59 | S | A | -0.7075 | Soluble |
| 62 | G | A | -1.1610 | Soluble |
| 63 | Q | A | -1.4267 | Soluble |
| 64 | S | A | -0.5782 | Soluble |
| 65 | T | A | 0.1139 | Aggregation-prone |
| 66 | Y | A | 0.5054 | Aggregation-prone |
| 67 | Y | A | -0.6993 | Soluble |
| 68 | R | A | -1.7706 | Soluble |
| 69 | R | A | -2.8646 | Soluble |
| 70 | E | A | -2.1364 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.5967 | Soluble |
| 74 | G | A | -1.9236 | Soluble |
| 75 | R | A | -1.8032 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.9409 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.5258 | Soluble |
| 80 | R | A | -1.1063 | Soluble |
| 81 | D | A | -1.5509 | Soluble |
| 82 | N | A | -1.7303 | Soluble |
| 83 | S | A | -1.6784 | Soluble |
| 84 | K | A | -2.4230 | Soluble |
| 85 | N | A | -1.8785 | Soluble |
| 86 | T | A | -1.1115 | Soluble |
| 87 | L | A | 0.0000 | Buried |
| 88 | Y | A | -0.5307 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.7223 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -2.0766 | Soluble |
| 93 | S | A | -1.5194 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.5339 | Soluble |
| 96 | A | A | -1.8279 | Soluble |
| 97 | E | A | -2.2980 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.6966 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.1387 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0881 | Aggregation-prone |
| 107 | R | A | 0.0000 | Buried |
| 108 | T | A | -1.0222 | Soluble |
| 109 | G | A | -1.8616 | Soluble |
| 110 | R | A | -3.3849 | Soluble |
| 111 | E | A | -3.6823 | Soluble |
| 111A | E | A | -3.4558 | Soluble |
| 112A | G | A | -2.4165 | Soluble |
| 112 | G | A | -1.7923 | Soluble |
| 113 | W | A | -0.9165 | Soluble |
| 114 | I | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.3197 | Soluble |
| 117 | Y | A | -0.2309 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4026 | Soluble |
| 121 | G | A | -0.7169 | Soluble |
| 122 | T | A | -0.2897 | Soluble |
| 123 | L | A | -0.0038 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.6107 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.8829 | Soluble |
| 128 | S | A | -0.6453 | Soluble |
| 129 | A | A | -0.5516 | Soluble |
| 130 | S | A | -0.7170 | Soluble |
| 131 | T | A | -0.9346 | Soluble |
| 132 | K | A | -1.6798 | Soluble |
| 133 | G | A | -1.7247 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.5483 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.1033 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.5129 | Soluble |
| 141 | P | A | -0.3378 | Soluble |
| 142 | C | A | -0.7861 | Soluble |
| 143 | S | A | -1.1817 | Soluble |
| 144 | R | A | -1.8772 | Soluble |
| 145 | S | A | -1.4778 | Soluble |
| 146 | T | A | -1.4974 | Soluble |
| 147 | S | A | -1.5242 | Soluble |
| 148 | E | A | -2.1377 | Soluble |
| 149 | S | A | -1.3014 | Soluble |
| 150 | T | A | -0.8493 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0669 | Aggregation-prone |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | -0.3019 | Soluble |
| 159 | D | A | -0.5040 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | -0.6680 | Soluble |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.9113 | Soluble |
| 164 | P | A | -0.8384 | Soluble |
| 165 | V | A | -0.7776 | Soluble |
| 166 | T | A | -0.6335 | Soluble |
| 167 | V | A | -0.1255 | Soluble |
| 168 | S | A | -0.3671 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -1.0150 | Soluble |
| 171 | S | A | -0.7081 | Soluble |
| 172 | G | A | -0.5618 | Soluble |
| 173 | A | A | -0.2248 | Soluble |
| 174 | L | A | -0.1039 | Soluble |
| 175 | T | A | -0.0944 | Soluble |
| 176 | S | A | -0.2907 | Soluble |
| 177 | G | A | -0.0210 | Soluble |
| 178 | V | A | 0.2898 | Aggregation-prone |
| 179 | H | A | -0.1211 | Soluble |
| 180 | T | A | 0.0350 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3309 | Soluble |
| 183 | A | A | 0.2797 | Aggregation-prone |
| 184 | V | A | 0.4184 | Aggregation-prone |
| 185 | L | A | 1.2154 | Aggregation-prone |
| 186 | Q | A | 0.1553 | Aggregation-prone |
| 187 | S | A | -0.3590 | Soluble |
| 188 | S | A | -0.3212 | Soluble |
| 189 | G | A | -0.1218 | Soluble |
| 190 | L | A | -0.1579 | Soluble |
| 191 | Y | A | 0.1993 | Aggregation-prone |
| 192 | S | A | 0.1860 | Aggregation-prone |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | 0.0567 | Aggregation-prone |
| 199 | V | A | 0.0550 | Aggregation-prone |
| 200 | P | A | -0.4102 | Soluble |
| 201 | S | A | -0.9739 | Soluble |
| 202 | S | A | -0.6871 | Soluble |
| 203 | S | A | -0.2214 | Soluble |
| 204 | L | A | -0.3362 | Soluble |
| 205 | G | A | -0.6708 | Soluble |
| 206 | T | A | -0.6089 | Soluble |
| 207 | Q | A | -0.9767 | Soluble |
| 208 | T | A | -1.2353 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | T | A | -1.9284 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.5946 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | D | A | -1.7948 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7621 | Soluble |
| 217 | P | A | -1.7662 | Soluble |
| 218 | S | A | -1.9107 | Soluble |
| 219 | N | A | -2.3805 | Soluble |
| 220 | T | A | -1.9643 | Soluble |
| 221 | K | A | -2.6232 | Soluble |
| 222 | V | A | -1.3554 | Soluble |
| 223 | D | A | -2.6275 | Soluble |
| 224 | K | A | -2.3061 | Soluble |
| 225 | R | A | -2.9421 | Soluble |
| 226 | V | A | -1.9302 | Soluble |
| 227 | E | A | -2.3787 | Soluble |
| 228 | S | A | -1.4443 | Soluble |
| 1 | E | B | -1.9468 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.5846 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.5544 | Soluble |
| 6 | Q | B | -0.9266 | Soluble |
| 7 | S | B | -0.7584 | Soluble |
| 8 | P | B | -0.4016 | Soluble |
| 9 | A | B | -0.2898 | Soluble |
| 10 | T | B | -0.1224 | Soluble |
| 11 | L | B | -0.1714 | Soluble |
| 12 | S | B | -0.5566 | Soluble |
| 13 | V | B | -1.5587 | Soluble |
| 14 | S | B | -2.0952 | Soluble |
| 15 | P | B | -2.3621 | Soluble |
| 16 | G | B | -2.4502 | Soluble |
| 17 | E | B | -3.6934 | Soluble |
| 18 | R | B | -3.5030 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.8944 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.9822 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.5668 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -1.2659 | Soluble |
| 27 | R | B | -2.6223 | Soluble |
| 28 | S | B | -2.6570 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 36 | R | B | -3.6664 | Soluble |
| 37 | R | B | -3.4425 | Soluble |
| 38 | E | B | -2.3583 | Soluble |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | -1.0626 | Soluble |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.8138 | Soluble |
| 46 | P | B | -1.4898 | Soluble |
| 47 | G | B | -1.6160 | Soluble |
| 48 | Q | B | -2.1566 | Soluble |
| 49 | A | B | 0.0000 | Buried |
| 50 | P | B | 0.0000 | Buried |
| 51 | E | B | -1.9842 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | -0.4106 | Soluble |
| 56 | G | B | -1.3384 | Soluble |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.9238 | Soluble |
| 66 | T | B | -0.8117 | Soluble |
| 67 | R | B | -1.6823 | Soluble |
| 68 | E | B | -1.1842 | Soluble |
| 69 | T | B | -0.8059 | Soluble |
| 70 | G | B | -0.7027 | Soluble |
| 71 | I | B | -0.7494 | Soluble |
| 72 | P | B | -0.6235 | Soluble |
| 74 | A | B | -0.8495 | Soluble |
| 75 | R | B | -1.5834 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.8277 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -0.9125 | Soluble |
| 80 | G | B | -1.8499 | Soluble |
| 83 | S | B | -2.5244 | Soluble |
| 84 | G | B | -2.8453 | Soluble |
| 85 | T | B | -2.7011 | Soluble |
| 86 | D | B | -2.8944 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.8331 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.9440 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | N | B | -2.9072 | Soluble |
| 93 | S | B | -2.5996 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.4852 | Soluble |
| 96 | A | B | -2.5354 | Soluble |
| 97 | E | B | -2.7823 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | A | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.3833 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | Y | B | 0.0000 | Buried |
| 108 | R | B | -2.5747 | Soluble |
| 109 | D | B | -1.7332 | Soluble |
| 114 | P | B | -0.9113 | Soluble |
| 115 | P | B | -0.9262 | Soluble |
| 116 | G | B | -0.5900 | Soluble |
| 117 | T | B | -0.3459 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -1.0942 | Soluble |
| 121 | G | B | -0.8509 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.3810 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -2.2129 | Soluble |
| 128 | R | B | -1.4000 | Soluble |
| 129 | T | B | -0.3471 | Soluble |
| 130 | V | B | -0.0682 | Soluble |
| 131 | A | B | -0.0800 | Soluble |
| 132 | A | B | -0.2561 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.0922 | Soluble |
| 135 | V | B | 0.0847 | Aggregation-prone |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4040 | Soluble |
| 140 | P | B | -0.7082 | Soluble |
| 141 | S | B | -1.4416 | Soluble |
| 142 | D | B | -2.7290 | Soluble |
| 143 | E | B | -2.5729 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.8786 | Soluble |
| 146 | K | B | -2.6697 | Soluble |
| 147 | S | B | -1.6328 | Soluble |
| 148 | G | B | -1.3421 | Soluble |
| 149 | T | B | -0.8511 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8625 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -2.0202 | Soluble |
| 162 | R | B | -3.1012 | Soluble |
| 163 | E | B | -3.2514 | Soluble |
| 164 | A | B | -2.4252 | Soluble |
| 165 | K | B | -2.3979 | Soluble |
| 166 | V | B | -1.2139 | Soluble |
| 167 | Q | B | -0.9013 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.9504 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.7463 | Soluble |
| 172 | N | B | -1.6082 | Soluble |
| 173 | A | B | -0.4887 | Soluble |
| 174 | L | B | -0.0045 | Soluble |
| 175 | Q | B | -0.5076 | Soluble |
| 176 | S | B | -0.5898 | Soluble |
| 177 | G | B | -0.9176 | Soluble |
| 178 | N | B | -1.3244 | Soluble |
| 179 | S | B | -1.3480 | Soluble |
| 180 | Q | B | -1.5698 | Soluble |
| 181 | E | B | -1.7859 | Soluble |
| 182 | S | B | 0.0000 | Buried |
| 183 | V | B | -0.5113 | Soluble |
| 184 | T | B | -1.0741 | Soluble |
| 185 | E | B | -2.2282 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.2764 | Soluble |
| 188 | S | B | -2.5780 | Soluble |
| 189 | K | B | -2.8938 | Soluble |
| 190 | D | B | -2.7209 | Soluble |
| 191 | S | B | -2.4131 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7439 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.3750 | Soluble |
| 201 | L | B | -0.6235 | Soluble |
| 202 | S | B | -0.9807 | Soluble |
| 203 | K | B | -2.0683 | Soluble |
| 204 | A | B | -1.7313 | Soluble |
| 205 | D | B | -2.2364 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.6767 | Soluble |
| 208 | K | B | -3.5869 | Soluble |
| 209 | H | B | -2.9686 | Soluble |
| 210 | K | B | -3.4862 | Soluble |
| 211 | V | B | -1.5359 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.6717 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -0.9670 | Soluble |
| 218 | H | B | -1.4005 | Soluble |
| 219 | Q | B | -1.5265 | Soluble |
| 220 | G | B | -0.7219 | Soluble |
| 221 | L | B | -0.1653 | Soluble |
| 222 | S | B | -0.2960 | Soluble |
| 223 | S | B | -0.0643 | Soluble |
| 224 | P | B | 0.1266 | Aggregation-prone |
| 225 | V | B | 1.3229 | Aggregation-prone |
| 226 | T | B | 0.0118 | Aggregation-prone |
| 227 | K | B | -0.7868 | Soluble |
| 228 | S | B | -0.8071 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -2.1283 | Soluble |
| 231 | R | B | -3.0117 | Soluble |
| 232 | G | B | -2.2977 | Soluble |
| 233 | E | B | -2.3525 | Soluble |
| 234 | C | B | -0.7909 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.8979 | 1.8561 | CSV PDB |
| 4.5 | -0.9444 | 1.785 | CSV PDB |
| 5.0 | -1.0022 | 1.6971 | CSV PDB |
| 5.5 | -1.0602 | 1.6026 | CSV PDB |
| 6.0 | -1.1057 | 1.5211 | CSV PDB |
| 6.5 | -1.128 | 1.4958 | CSV PDB |
| 7.0 | -1.1254 | 1.4797 | CSV PDB |
| 7.5 | -1.1053 | 1.4696 | CSV PDB |
| 8.0 | -1.0759 | 1.5223 | CSV PDB |
| 8.5 | -1.0405 | 1.5878 | CSV PDB |
| 9.0 | -1.0002 | 1.6534 | CSV PDB |