Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCARSPNPYYYDSSGYYYPGAFDIWGQGTMVTVSSASVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGGLTQPPSVSVAPGQTARITCGGNNIGSKSVHWYQQKPGQAPVLVVYDDSDRPSGIPERFSGSNSGNTATLTISRVEAGDEADYYCQVWDSSSDHYVFGTGTKVTVLSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.1119 | Soluble |
| 2 | V | A | -0.2039 | Soluble |
| 3 | Q | A | -0.7628 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.0482 | Soluble |
| 6 | Q | A | -0.3110 | Soluble |
| 7 | S | A | -0.6276 | Soluble |
| 8 | G | A | -0.2880 | Soluble |
| 9 | A | A | 0.1408 | Aggregation-prone |
| 11 | E | A | 0.1139 | Aggregation-prone |
| 12 | V | A | 0.9885 | Aggregation-prone |
| 13 | K | A | -0.8938 | Soluble |
| 14 | K | A | -2.3460 | Soluble |
| 15 | P | A | -2.6396 | Soluble |
| 16 | G | A | -2.2551 | Soluble |
| 17 | A | A | -1.7523 | Soluble |
| 18 | S | A | -1.8439 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.8018 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6374 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -0.5753 | Soluble |
| 25 | A | A | -0.1761 | Soluble |
| 26 | S | A | -0.4249 | Soluble |
| 27 | G | A | -0.6148 | Soluble |
| 28 | Y | A | -0.2593 | Soluble |
| 29 | T | A | -0.0761 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | -0.5406 | Soluble |
| 36 | G | A | 0.0000 | Buried |
| 37 | Y | A | 0.0000 | Buried |
| 38 | Y | A | -0.0902 | Soluble |
| 39 | M | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.6080 | Soluble |
| 45 | A | A | -0.9854 | Soluble |
| 46 | P | A | -1.0591 | Soluble |
| 47 | G | A | -1.2411 | Soluble |
| 48 | Q | A | -1.6804 | Soluble |
| 49 | G | A | -1.0767 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.5703 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | -0.0699 | Soluble |
| 56 | I | A | 0.0000 | Buried |
| 57 | N | A | -0.8263 | Soluble |
| 58 | P | A | 0.0000 | Buried |
| 59 | N | A | -1.6458 | Soluble |
| 62 | S | A | -1.0685 | Soluble |
| 63 | G | A | -0.9959 | Soluble |
| 64 | G | A | -0.7800 | Soluble |
| 65 | T | A | -0.4340 | Soluble |
| 66 | N | A | -1.0156 | Soluble |
| 67 | Y | A | -1.2042 | Soluble |
| 68 | A | A | -1.7710 | Soluble |
| 69 | Q | A | -2.6224 | Soluble |
| 70 | K | A | -2.7435 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.5120 | Soluble |
| 74 | G | A | -1.8995 | Soluble |
| 75 | R | A | -1.7954 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.8728 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.6570 | Soluble |
| 80 | R | A | -1.1125 | Soluble |
| 81 | D | A | -1.0870 | Soluble |
| 82 | T | A | -0.5666 | Soluble |
| 83 | S | A | 0.0616 | Aggregation-prone |
| 84 | I | A | 0.7300 | Aggregation-prone |
| 85 | S | A | -0.0760 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.7895 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.5019 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -1.9317 | Soluble |
| 93 | R | A | -2.8733 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.3907 | Soluble |
| 96 | S | A | -2.3521 | Soluble |
| 97 | D | A | -2.6177 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.8428 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2239 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | P | A | 0.0000 | Buried |
| 109 | N | A | 0.0000 | Buried |
| 110 | P | A | 1.0229 | Aggregation-prone |
| 111 | Y | A | 1.6892 | Aggregation-prone |
| 111A | Y | A | 1.4748 | Aggregation-prone |
| 111B | Y | A | 1.5565 | Aggregation-prone |
| 111C | D | A | 0.2122 | Aggregation-prone |
| 111D | S | A | -0.2390 | Soluble |
| 112E | S | A | -0.1663 | Soluble |
| 112D | G | A | -0.0150 | Soluble |
| 112C | Y | A | 0.6101 | Aggregation-prone |
| 112B | Y | A | 0.9584 | Aggregation-prone |
| 112A | Y | A | 0.0000 | Buried |
| 112 | P | A | 0.5497 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | A | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | 0.3206 | Aggregation-prone |
| 117 | I | A | 0.3804 | Aggregation-prone |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3362 | Soluble |
| 121 | G | A | -0.6785 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | M | A | 0.3781 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.2699 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0570 | Soluble |
| 128 | S | A | -0.9932 | Soluble |
| 129 | A | A | -0.1086 | Soluble |
| 130 | S | A | 0.6197 | Aggregation-prone |
| 131 | V | A | 1.3709 | Aggregation-prone |
| 132 | A | A | 0.5463 | Aggregation-prone |
| 133 | A | A | 0.0882 | Aggregation-prone |
| 134 | P | A | -0.2024 | Soluble |
| 135 | S | A | -0.2529 | Soluble |
| 136 | V | A | -0.0665 | Soluble |
| 137 | F | A | 0.0000 | Buried |
| 138 | I | A | 0.0618 | Aggregation-prone |
| 139 | F | A | 0.0000 | Buried |
| 140 | P | A | -0.6505 | Soluble |
| 141 | P | A | -0.5781 | Soluble |
| 142 | S | A | -1.3281 | Soluble |
| 143 | D | A | -2.6032 | Soluble |
| 144 | E | A | -2.1818 | Soluble |
| 145 | Q | A | 0.0000 | Buried |
| 146 | L | A | -1.8258 | Soluble |
| 147 | K | A | -2.5610 | Soluble |
| 148 | S | A | -1.5549 | Soluble |
| 149 | G | A | -1.2422 | Soluble |
| 150 | T | A | -0.8277 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | S | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | V | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | L | A | 0.0000 | Buried |
| 158 | N | A | 0.0000 | Buried |
| 159 | N | A | -0.8013 | Soluble |
| 160 | F | A | 0.0000 | Buried |
| 161 | Y | A | -0.2958 | Soluble |
| 162 | P | A | 0.0000 | Buried |
| 163 | R | A | -1.2622 | Soluble |
| 164 | E | A | -2.5540 | Soluble |
| 165 | A | A | -1.9825 | Soluble |
| 166 | K | A | -2.0912 | Soluble |
| 167 | V | A | -1.0183 | Soluble |
| 168 | Q | A | -0.5952 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | K | A | -0.5686 | Soluble |
| 171 | V | A | 0.0000 | Buried |
| 172 | D | A | -2.1782 | Soluble |
| 173 | N | A | -1.6521 | Soluble |
| 174 | A | A | -0.3207 | Soluble |
| 175 | L | A | 0.7765 | Aggregation-prone |
| 176 | Q | A | -0.0943 | Soluble |
| 177 | S | A | -0.4718 | Soluble |
| 178 | G | A | -0.8908 | Soluble |
| 179 | N | A | -0.9675 | Soluble |
| 180 | S | A | -0.9326 | Soluble |
| 181 | Q | A | -0.8488 | Soluble |
| 182 | E | A | -0.6318 | Soluble |
| 183 | S | A | 0.0407 | Aggregation-prone |
| 184 | V | A | 0.6106 | Aggregation-prone |
| 185 | T | A | -0.3731 | Soluble |
| 186 | E | A | -1.6325 | Soluble |
| 187 | Q | A | -2.3684 | Soluble |
| 188 | D | A | -3.2031 | Soluble |
| 189 | S | A | -2.3362 | Soluble |
| 190 | K | A | -2.7931 | Soluble |
| 191 | D | A | -2.4224 | Soluble |
| 192 | S | A | -2.0885 | Soluble |
| 193 | T | A | 0.0000 | Buried |
| 194 | Y | A | -0.9767 | Soluble |
| 195 | S | A | 0.0000 | Buried |
| 196 | L | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | S | A | 0.0000 | Buried |
| 199 | T | A | -0.3924 | Soluble |
| 200 | L | A | 0.0000 | Buried |
| 201 | T | A | -0.2030 | Soluble |
| 202 | L | A | -0.6806 | Soluble |
| 203 | S | A | -1.1964 | Soluble |
| 204 | K | A | -2.1739 | Soluble |
| 205 | A | A | -2.2995 | Soluble |
| 206 | D | A | -3.2965 | Soluble |
| 207 | Y | A | -2.7365 | Soluble |
| 208 | E | A | -4.0277 | Soluble |
| 209 | K | A | -3.9308 | Soluble |
| 210 | H | A | -3.3158 | Soluble |
| 211 | K | A | -3.8651 | Soluble |
| 212 | V | A | -2.3506 | Soluble |
| 213 | Y | A | 0.0000 | Buried |
| 214 | A | A | 0.0000 | Buried |
| 215 | C | A | 0.0000 | Buried |
| 216 | E | A | -0.9706 | Soluble |
| 217 | V | A | 0.0000 | Buried |
| 218 | T | A | -1.2017 | Soluble |
| 219 | H | A | 0.0000 | Buried |
| 220 | Q | A | -1.1146 | Soluble |
| 221 | G | A | -0.0808 | Soluble |
| 222 | L | A | -0.0596 | Soluble |
| 223 | S | A | -0.4221 | Soluble |
| 224 | S | A | -0.3847 | Soluble |
| 225 | P | A | -0.2705 | Soluble |
| 226 | V | A | -0.1355 | Soluble |
| 227 | T | A | -0.6685 | Soluble |
| 228 | K | A | -0.9386 | Soluble |
| 229 | S | A | -0.7435 | Soluble |
| 230 | F | A | -1.0691 | Soluble |
| 231 | N | A | -2.5756 | Soluble |
| 232 | R | A | -3.0490 | Soluble |
| 233 | G | A | -1.4905 | Soluble |
| 3 | G | B | -0.6998 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.3004 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | P | B | -0.3699 | Soluble |
| 8 | P | B | -0.6301 | Soluble |
| 9 | S | B | -0.6349 | Soluble |
| 11 | V | B | -0.4443 | Soluble |
| 12 | S | B | -0.3980 | Soluble |
| 13 | V | B | -0.5783 | Soluble |
| 14 | A | B | -0.8332 | Soluble |
| 15 | P | B | -1.7410 | Soluble |
| 16 | G | B | -2.2456 | Soluble |
| 17 | Q | B | -2.3508 | Soluble |
| 18 | T | B | -1.9546 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | R | B | -1.9363 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.5863 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | G | B | -1.1654 | Soluble |
| 25 | G | B | -1.7604 | Soluble |
| 26 | N | B | -2.6677 | Soluble |
| 27 | N | B | -2.8639 | Soluble |
| 28 | I | B | 0.0000 | Buried |
| 29 | G | B | -1.9387 | Soluble |
| 36 | S | B | -1.4674 | Soluble |
| 37 | K | B | -1.5640 | Soluble |
| 38 | S | B | -0.9334 | Soluble |
| 39 | V | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.5626 | Soluble |
| 46 | P | B | -1.4199 | Soluble |
| 47 | G | B | -1.4465 | Soluble |
| 48 | Q | B | -1.8308 | Soluble |
| 49 | A | B | -0.8631 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | V | B | 1.0061 | Aggregation-prone |
| 52 | L | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | V | B | 0.0000 | Buried |
| 55 | Y | B | -1.0484 | Soluble |
| 56 | D | B | -2.0600 | Soluble |
| 57 | D | B | -2.6349 | Soluble |
| 65 | S | B | -2.2761 | Soluble |
| 66 | D | B | -2.4059 | Soluble |
| 67 | R | B | -1.6293 | Soluble |
| 68 | P | B | -0.3355 | Soluble |
| 69 | S | B | -0.4522 | Soluble |
| 70 | G | B | -0.6878 | Soluble |
| 71 | I | B | -0.5570 | Soluble |
| 72 | P | B | -1.1264 | Soluble |
| 74 | E | B | -2.2407 | Soluble |
| 75 | R | B | -1.8333 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -1.6646 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -1.1931 | Soluble |
| 80 | N | B | -1.7137 | Soluble |
| 83 | S | B | -1.4670 | Soluble |
| 84 | G | B | -2.1491 | Soluble |
| 85 | N | B | -2.7625 | Soluble |
| 86 | T | B | -1.5891 | Soluble |
| 87 | A | B | 0.0000 | Buried |
| 88 | T | B | -0.9556 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -1.2415 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.1747 | Soluble |
| 93 | R | B | -2.9769 | Soluble |
| 94 | V | B | 0.0000 | Buried |
| 95 | E | B | -2.7818 | Soluble |
| 96 | A | B | -1.2212 | Soluble |
| 97 | G | B | -1.2720 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | E | B | -1.4528 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | D | B | -1.2233 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | V | B | 0.0000 | Buried |
| 107 | W | B | -0.4290 | Soluble |
| 108 | D | B | -1.0537 | Soluble |
| 109 | S | B | -0.8973 | Soluble |
| 110 | S | B | -0.8124 | Soluble |
| 113 | S | B | -0.9476 | Soluble |
| 114 | D | B | -1.2348 | Soluble |
| 115 | H | B | -1.3864 | Soluble |
| 116 | Y | B | 0.0000 | Buried |
| 117 | V | B | -0.0024 | Soluble |
| 118 | F | B | 0.1644 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | T | B | -0.4332 | Soluble |
| 121 | G | B | -0.7109 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.3419 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | -0.5551 | Soluble |
| 126 | V | B | -0.4922 | Soluble |
| 127 | L | B | -0.0377 | Soluble |
| 128 | S | B | -0.0854 | Soluble |
| 129 | S | B | -0.2245 | Soluble |
| 130 | A | B | -0.3384 | Soluble |
| 131 | S | B | -0.5190 | Soluble |
| 132 | T | B | -0.8789 | Soluble |
| 133 | K | B | -1.2326 | Soluble |
| 134 | G | B | -1.3828 | Soluble |
| 135 | P | B | -0.6284 | Soluble |
| 136 | S | B | -0.3068 | Soluble |
| 137 | V | B | 0.0000 | Buried |
| 138 | F | B | -0.5224 | Soluble |
| 139 | P | B | -0.9893 | Soluble |
| 140 | L | B | 0.0000 | Buried |
| 141 | A | B | -1.1277 | Soluble |
| 142 | P | B | 0.0000 | Buried |
| 143 | S | B | -0.9678 | Soluble |
| 144 | S | B | -0.4685 | Soluble |
| 145 | K | B | 0.0000 | Buried |
| 146 | S | B | -0.5167 | Soluble |
| 147 | T | B | -0.4758 | Soluble |
| 148 | S | B | -0.5784 | Soluble |
| 149 | G | B | -0.6799 | Soluble |
| 150 | G | B | -0.7505 | Soluble |
| 151 | T | B | -0.5239 | Soluble |
| 152 | A | B | 0.0000 | Buried |
| 153 | A | B | 0.0000 | Buried |
| 154 | L | B | 0.0000 | Buried |
| 155 | G | B | 0.0000 | Buried |
| 156 | C | B | 0.0000 | Buried |
| 157 | L | B | 0.0000 | Buried |
| 158 | V | B | 0.0000 | Buried |
| 159 | K | B | 0.0000 | Buried |
| 160 | D | B | -0.3642 | Soluble |
| 161 | Y | B | 0.0000 | Buried |
| 162 | F | B | 0.0000 | Buried |
| 163 | P | B | -0.7717 | Soluble |
| 164 | E | B | -0.9488 | Soluble |
| 165 | P | B | -1.0066 | Soluble |
| 166 | V | B | -0.8305 | Soluble |
| 167 | T | B | -0.7083 | Soluble |
| 168 | V | B | -0.4362 | Soluble |
| 169 | S | B | -0.4488 | Soluble |
| 170 | W | B | 0.0000 | Buried |
| 171 | N | B | -0.7704 | Soluble |
| 172 | S | B | -0.6627 | Soluble |
| 173 | G | B | -0.4903 | Soluble |
| 174 | A | B | -0.1845 | Soluble |
| 175 | L | B | 0.0785 | Aggregation-prone |
| 176 | T | B | -0.0302 | Soluble |
| 177 | S | B | -0.0506 | Soluble |
| 178 | G | B | 0.0000 | Buried |
| 179 | V | B | 0.3375 | Aggregation-prone |
| 180 | H | B | 0.0000 | Buried |
| 181 | T | B | 0.1396 | Aggregation-prone |
| 182 | F | B | 0.0000 | Buried |
| 183 | P | B | 0.0993 | Aggregation-prone |
| 184 | A | B | 0.2756 | Aggregation-prone |
| 185 | V | B | 0.7707 | Aggregation-prone |
| 186 | L | B | 1.0997 | Aggregation-prone |
| 187 | Q | B | 0.3242 | Aggregation-prone |
| 188 | S | B | -0.0900 | Soluble |
| 189 | S | B | -0.1673 | Soluble |
| 190 | G | B | 0.0476 | Aggregation-prone |
| 191 | L | B | 0.0441 | Aggregation-prone |
| 192 | Y | B | 0.3635 | Aggregation-prone |
| 193 | S | B | 0.0000 | Buried |
| 194 | L | B | 0.0000 | Buried |
| 195 | S | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | V | B | 0.0000 | Buried |
| 199 | T | B | -0.0247 | Soluble |
| 200 | V | B | 0.0000 | Buried |
| 201 | P | B | -0.4432 | Soluble |
| 202 | S | B | -0.6273 | Soluble |
| 203 | S | B | -0.5828 | Soluble |
| 204 | S | B | -0.6375 | Soluble |
| 205 | L | B | -0.6788 | Soluble |
| 206 | G | B | -0.8864 | Soluble |
| 207 | T | B | -0.8372 | Soluble |
| 208 | Q | B | -1.2020 | Soluble |
| 209 | T | B | -1.2070 | Soluble |
| 210 | Y | B | 0.0000 | Buried |
| 211 | I | B | -1.5512 | Soluble |
| 212 | C | B | 0.0000 | Buried |
| 213 | N | B | -1.5616 | Soluble |
| 214 | V | B | 0.0000 | Buried |
| 215 | N | B | -2.0642 | Soluble |
| 216 | H | B | 0.0000 | Buried |
| 217 | K | B | -2.8251 | Soluble |
| 218 | P | B | -1.7202 | Soluble |
| 219 | S | B | -1.9327 | Soluble |
| 220 | N | B | -2.5819 | Soluble |
| 221 | T | B | -2.1018 | Soluble |
| 222 | K | B | -2.6908 | Soluble |
| 223 | V | B | -1.5068 | Soluble |
| 224 | D | B | -2.5562 | Soluble |
| 225 | K | B | -2.0173 | Soluble |
| 226 | K | B | -2.6311 | Soluble |
| 227 | V | B | 0.0000 | Buried |
| 228 | E | B | -2.7705 | Soluble |
| 229 | P | B | -2.1368 | Soluble |
| 230 | K | B | -2.2187 | Soluble |
| 231 | S | B | -0.8278 | Soluble |
| 232 | C | B | -0.0700 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.6775 | 2.2095 | CSV PDB |
| 4.5 | -0.7247 | 2.1925 | CSV PDB |
| 5.0 | -0.7779 | 2.1752 | CSV PDB |
| 5.5 | -0.8272 | 2.158 | CSV PDB |
| 6.0 | -0.8625 | 2.1408 | CSV PDB |
| 6.5 | -0.8771 | 2.1238 | CSV PDB |
| 7.0 | -0.8719 | 2.1076 | CSV PDB |
| 7.5 | -0.8541 | 2.0935 | CSV PDB |
| 8.0 | -0.829 | 2.0829 | CSV PDB |
| 8.5 | -0.7972 | 2.0756 | CSV PDB |
| 9.0 | -0.7579 | 2.067 | CSV PDB |