Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTWIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGFMFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSDIQMTQSPSSLSASVGDRVTITCRASQDIPRSISGYVAWYQQKPGKAPKLLIYWGSYLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1137 | Soluble |
| 2 | V | A | -1.2675 | Soluble |
| 3 | Q | A | -1.1713 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 1.0733 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.3664 | Soluble |
| 8 | G | A | -0.8242 | Soluble |
| 9 | G | A | -0.6709 | Soluble |
| 11 | G | A | -0.3667 | Soluble |
| 12 | L | A | -0.1011 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.7184 | Soluble |
| 15 | P | A | -1.9432 | Soluble |
| 16 | G | A | -1.6435 | Soluble |
| 17 | G | A | -1.3012 | Soluble |
| 18 | S | A | -1.4988 | Soluble |
| 19 | L | A | -1.2351 | Soluble |
| 20 | R | A | -2.1058 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.3523 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.0338 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.1837 | Soluble |
| 27 | G | A | -1.4184 | Soluble |
| 28 | F | A | -1.5518 | Soluble |
| 29 | N | A | -2.5744 | Soluble |
| 30 | I | A | 0.0000 | Buried |
| 35 | K | A | -3.0061 | Soluble |
| 36 | D | A | -2.6206 | Soluble |
| 37 | T | A | 0.0000 | Buried |
| 38 | W | A | -0.0877 | Soluble |
| 39 | I | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.8039 | Soluble |
| 45 | A | A | -1.1883 | Soluble |
| 46 | P | A | -0.9651 | Soluble |
| 47 | G | A | -1.4689 | Soluble |
| 48 | K | A | -2.3800 | Soluble |
| 49 | G | A | -1.6460 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.0729 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | R | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | Y | A | -0.4069 | Soluble |
| 58 | P | A | 0.0000 | Buried |
| 59 | T | A | -1.4220 | Soluble |
| 62 | N | A | -1.3280 | Soluble |
| 63 | G | A | -0.5879 | Soluble |
| 64 | Y | A | 0.2831 | Aggregation-prone |
| 65 | T | A | -0.0413 | Soluble |
| 66 | R | A | -0.7819 | Soluble |
| 67 | Y | A | -1.1582 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | D | A | -2.5195 | Soluble |
| 70 | S | A | -1.5798 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.6773 | Soluble |
| 74 | G | A | -1.8092 | Soluble |
| 75 | R | A | -1.5072 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -1.1256 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.2156 | Soluble |
| 80 | A | A | -0.9195 | Soluble |
| 81 | D | A | -1.4198 | Soluble |
| 82 | T | A | -1.8851 | Soluble |
| 83 | S | A | -1.6178 | Soluble |
| 84 | K | A | -2.2399 | Soluble |
| 85 | N | A | -1.8827 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.5715 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.6368 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.9739 | Soluble |
| 93 | S | A | -1.5011 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.6434 | Soluble |
| 96 | A | A | -1.8547 | Soluble |
| 97 | E | A | -2.3043 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7690 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2157 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | R | A | 0.0380 | Aggregation-prone |
| 107 | W | A | 0.0000 | Buried |
| 108 | G | A | 0.0000 | Buried |
| 109 | G | A | 0.3474 | Aggregation-prone |
| 110 | F | A | 1.7984 | Aggregation-prone |
| 111 | M | A | 1.3644 | Aggregation-prone |
| 112 | F | A | 1.4800 | Aggregation-prone |
| 113 | Y | A | 0.9991 | Aggregation-prone |
| 114 | A | A | 0.0000 | Buried |
| 115 | M | A | 0.0000 | Buried |
| 116 | D | A | -0.0305 | Soluble |
| 117 | Y | A | 0.0477 | Aggregation-prone |
| 118 | W | A | -0.2339 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.2712 | Soluble |
| 121 | G | A | 0.0000 | Buried |
| 122 | T | A | -0.0306 | Soluble |
| 123 | L | A | 0.0241 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.5065 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.8427 | Soluble |
| 128 | S | A | -0.7289 | Soluble |
| 129 | A | A | -0.4520 | Soluble |
| 130 | S | A | -0.5594 | Soluble |
| 131 | T | A | -0.5950 | Soluble |
| 132 | K | A | -1.1831 | Soluble |
| 133 | G | A | -1.3697 | Soluble |
| 134 | P | A | -0.5769 | Soluble |
| 135 | S | A | -0.4093 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.6610 | Soluble |
| 138 | P | A | -1.1887 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.2076 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -0.7572 | Soluble |
| 143 | S | A | -0.6003 | Soluble |
| 144 | G | A | -0.8623 | Soluble |
| 145 | G | A | -0.9243 | Soluble |
| 146 | T | A | -0.6630 | Soluble |
| 147 | A | A | -0.3755 | Soluble |
| 148 | A | A | 0.0000 | Buried |
| 149 | L | A | 0.0000 | Buried |
| 150 | G | A | 0.0000 | Buried |
| 151 | C | A | 0.0000 | Buried |
| 152 | L | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | K | A | 0.0000 | Buried |
| 155 | D | A | -0.3511 | Soluble |
| 156 | Y | A | 0.0000 | Buried |
| 157 | F | A | 0.0000 | Buried |
| 158 | P | A | 0.0000 | Buried |
| 159 | E | A | -0.3763 | Soluble |
| 160 | P | A | -0.6234 | Soluble |
| 161 | V | A | -0.5794 | Soluble |
| 162 | T | A | -0.4921 | Soluble |
| 163 | V | A | -0.3020 | Soluble |
| 164 | S | A | -0.3870 | Soluble |
| 165 | W | A | 0.0000 | Buried |
| 166 | N | A | -0.8261 | Soluble |
| 167 | S | A | -0.6813 | Soluble |
| 168 | G | A | -0.5449 | Soluble |
| 169 | A | A | -0.2604 | Soluble |
| 170 | L | A | -0.0491 | Soluble |
| 171 | T | A | -0.1997 | Soluble |
| 172 | S | A | -0.2020 | Soluble |
| 173 | G | A | -0.2583 | Soluble |
| 174 | V | A | 0.1356 | Aggregation-prone |
| 175 | H | A | -0.3230 | Soluble |
| 176 | T | A | 0.0368 | Aggregation-prone |
| 177 | F | A | 0.0000 | Buried |
| 178 | P | A | -0.2707 | Soluble |
| 179 | A | A | 0.3555 | Aggregation-prone |
| 180 | V | A | 0.7860 | Aggregation-prone |
| 181 | L | A | 1.4892 | Aggregation-prone |
| 182 | Q | A | 0.4617 | Aggregation-prone |
| 183 | S | A | -0.0117 | Soluble |
| 184 | S | A | -0.1900 | Soluble |
| 185 | G | A | 0.0590 | Aggregation-prone |
| 186 | L | A | 0.1983 | Aggregation-prone |
| 187 | Y | A | 0.5749 | Aggregation-prone |
| 188 | S | A | 0.0000 | Buried |
| 189 | L | A | 0.0000 | Buried |
| 190 | S | A | 0.0000 | Buried |
| 191 | S | A | 0.0000 | Buried |
| 192 | V | A | 0.0000 | Buried |
| 193 | V | A | 0.0000 | Buried |
| 194 | T | A | -0.2060 | Soluble |
| 195 | V | A | 0.0000 | Buried |
| 196 | P | A | -0.6877 | Soluble |
| 197 | S | A | -0.6482 | Soluble |
| 198 | S | A | -0.6544 | Soluble |
| 199 | S | A | -0.7276 | Soluble |
| 200 | L | A | -0.8959 | Soluble |
| 201 | G | A | -1.0290 | Soluble |
| 202 | T | A | -0.8331 | Soluble |
| 203 | Q | A | -1.4589 | Soluble |
| 204 | T | A | -1.2406 | Soluble |
| 205 | Y | A | 0.0000 | Buried |
| 206 | I | A | -1.2958 | Soluble |
| 207 | C | A | 0.0000 | Buried |
| 208 | N | A | -1.4372 | Soluble |
| 209 | V | A | 0.0000 | Buried |
| 210 | N | A | -1.8186 | Soluble |
| 211 | H | A | 0.0000 | Buried |
| 212 | K | A | -2.7234 | Soluble |
| 213 | P | A | -1.5744 | Soluble |
| 214 | S | A | -1.8066 | Soluble |
| 215 | N | A | -2.5234 | Soluble |
| 216 | T | A | -2.0225 | Soluble |
| 217 | K | A | -2.6670 | Soluble |
| 218 | V | A | -1.7298 | Soluble |
| 219 | D | A | -2.5194 | Soluble |
| 220 | K | A | -2.1497 | Soluble |
| 221 | K | A | -2.4719 | Soluble |
| 222 | V | A | 0.0000 | Buried |
| 223 | E | A | -2.8886 | Soluble |
| 224 | P | A | -1.9320 | Soluble |
| 225 | K | A | -2.5564 | Soluble |
| 226 | S | A | -1.2781 | Soluble |
| 1 | D | B | -2.0567 | Soluble |
| 2 | I | B | -1.5599 | Soluble |
| 3 | Q | B | -1.7544 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -1.4086 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.9600 | Soluble |
| 8 | P | B | -0.7204 | Soluble |
| 9 | S | B | -1.0161 | Soluble |
| 10 | S | B | -1.0161 | Soluble |
| 11 | L | B | -0.6719 | Soluble |
| 12 | S | B | -0.8666 | Soluble |
| 13 | A | B | -1.0061 | Soluble |
| 14 | S | B | -0.9114 | Soluble |
| 15 | V | B | -0.1428 | Soluble |
| 16 | G | B | -0.8900 | Soluble |
| 17 | D | B | -1.7475 | Soluble |
| 18 | R | B | -2.3649 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.5096 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.7751 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.7963 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -2.1535 | Soluble |
| 27 | Q | B | -2.7424 | Soluble |
| 28 | D | B | -2.8797 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 30 | P | B | -1.4113 | Soluble |
| 31 | R | B | -1.9703 | Soluble |
| 34 | S | B | -0.5711 | Soluble |
| 35 | I | B | 0.5962 | Aggregation-prone |
| 36 | S | B | 0.2213 | Aggregation-prone |
| 37 | G | B | 0.0000 | Buried |
| 38 | Y | B | 0.8208 | Aggregation-prone |
| 39 | V | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | -1.2885 | Soluble |
| 45 | K | B | -1.7718 | Soluble |
| 46 | P | B | -1.5123 | Soluble |
| 47 | G | B | -1.8092 | Soluble |
| 48 | K | B | -2.5133 | Soluble |
| 49 | A | B | -1.5143 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.2629 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 1.0915 | Aggregation-prone |
| 56 | W | B | 1.0177 | Aggregation-prone |
| 57 | G | B | 0.3331 | Aggregation-prone |
| 65 | S | B | 0.5224 | Aggregation-prone |
| 66 | Y | B | 1.5107 | Aggregation-prone |
| 67 | L | B | 1.2182 | Aggregation-prone |
| 68 | Y | B | 0.5157 | Aggregation-prone |
| 69 | S | B | -0.0625 | Soluble |
| 70 | G | B | -0.4580 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | -0.3410 | Soluble |
| 74 | S | B | -0.3775 | Soluble |
| 75 | R | B | -0.7336 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0185 | Soluble |
| 78 | G | B | 0.0096 | Aggregation-prone |
| 79 | S | B | -0.4655 | Soluble |
| 80 | G | B | -1.0355 | Soluble |
| 83 | S | B | -1.0609 | Soluble |
| 84 | G | B | -1.7091 | Soluble |
| 85 | T | B | -2.0710 | Soluble |
| 86 | D | B | -1.7623 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7070 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6048 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.3576 | Soluble |
| 93 | S | B | -1.2336 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.1132 | Soluble |
| 96 | P | B | -1.4930 | Soluble |
| 97 | E | B | -1.6291 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | 0.0000 | Buried |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | Y | B | 0.4631 | Aggregation-prone |
| 109 | T | B | -0.1307 | Soluble |
| 114 | T | B | -0.1207 | Soluble |
| 115 | P | B | -0.3630 | Soluble |
| 116 | P | B | 0.0000 | Buried |
| 117 | T | B | -0.5244 | Soluble |
| 118 | F | B | -0.4452 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.8674 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -2.0724 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.3790 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.3358 | Soluble |
| 128 | R | B | -0.9683 | Soluble |
| 129 | T | B | -0.1494 | Soluble |
| 130 | V | B | 0.3236 | Aggregation-prone |
| 131 | A | B | -0.0613 | Soluble |
| 132 | A | B | -0.1579 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2190 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0382 | Aggregation-prone |
| 137 | I | B | 0.0787 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4557 | Soluble |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | -1.7765 | Soluble |
| 142 | D | B | -3.0752 | Soluble |
| 143 | E | B | -2.8738 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.2815 | Soluble |
| 146 | K | B | -2.8396 | Soluble |
| 147 | S | B | -1.7803 | Soluble |
| 148 | G | B | -1.3185 | Soluble |
| 149 | T | B | -1.0773 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -1.0564 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.5281 | Soluble |
| 162 | R | B | -2.5278 | Soluble |
| 163 | E | B | -2.9436 | Soluble |
| 164 | A | B | -2.1335 | Soluble |
| 165 | K | B | -2.2804 | Soluble |
| 166 | V | B | 0.0000 | Buried |
| 167 | Q | B | -0.9916 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -1.1315 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.9961 | Soluble |
| 172 | N | B | -1.7677 | Soluble |
| 173 | A | B | -0.6224 | Soluble |
| 174 | L | B | 0.0090 | Aggregation-prone |
| 175 | Q | B | -0.4997 | Soluble |
| 176 | S | B | -0.5638 | Soluble |
| 177 | G | B | -0.8548 | Soluble |
| 178 | N | B | -0.7692 | Soluble |
| 179 | S | B | -0.9553 | Soluble |
| 180 | Q | B | -0.9054 | Soluble |
| 181 | E | B | -1.4417 | Soluble |
| 182 | S | B | -0.6957 | Soluble |
| 183 | V | B | -0.4389 | Soluble |
| 184 | T | B | -1.0187 | Soluble |
| 185 | E | B | -2.1736 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.0648 | Soluble |
| 188 | S | B | -2.1400 | Soluble |
| 189 | K | B | -2.5655 | Soluble |
| 190 | D | B | -1.9874 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.5019 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4196 | Soluble |
| 201 | L | B | -0.6534 | Soluble |
| 202 | S | B | -1.0610 | Soluble |
| 203 | K | B | -2.0432 | Soluble |
| 204 | A | B | -1.8280 | Soluble |
| 205 | D | B | -2.5037 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.0222 | Soluble |
| 208 | K | B | -3.3983 | Soluble |
| 209 | H | B | -2.9225 | Soluble |
| 210 | K | B | -2.9888 | Soluble |
| 211 | V | B | -1.2901 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.9418 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -1.2357 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2480 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6745 | Soluble |
| 220 | G | B | -0.4362 | Soluble |
| 221 | L | B | -0.2434 | Soluble |
| 222 | S | B | -0.4614 | Soluble |
| 223 | S | B | -0.4327 | Soluble |
| 224 | P | B | -0.6022 | Soluble |
| 225 | V | B | -0.0960 | Soluble |
| 226 | T | B | -0.5294 | Soluble |
| 227 | K | B | -0.6418 | Soluble |
| 228 | S | B | -0.5107 | Soluble |
| 229 | F | B | -0.8403 | Soluble |
| 230 | N | B | -1.7787 | Soluble |
| 231 | R | B | -2.3516 | Soluble |
| 232 | G | B | -2.0401 | Soluble |
| 233 | E | B | -2.4749 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7256 | 4.7979 | CSV PDB |
| 4.5 | -0.7681 | 4.7496 | CSV PDB |
| 5.0 | -0.8163 | 4.6964 | CSV PDB |
| 5.5 | -0.8606 | 4.6415 | CSV PDB |
| 6.0 | -0.8902 | 4.5861 | CSV PDB |
| 6.5 | -0.8965 | 4.5306 | CSV PDB |
| 7.0 | -0.8801 | 4.4754 | CSV PDB |
| 7.5 | -0.849 | 4.4214 | CSV PDB |
| 8.0 | -0.8097 | 4.3706 | CSV PDB |
| 8.5 | -0.7638 | 4.3278 | CSV PDB |
| 9.0 | -0.7109 | 4.2989 | CSV PDB |