Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.4456 | Soluble |
| 2 | V | A | -1.1041 | Soluble |
| 3 | Q | A | -1.6113 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.1248 | Soluble |
| 6 | Q | A | -0.3931 | Soluble |
| 7 | S | A | -0.6640 | Soluble |
| 8 | G | A | -0.3336 | Soluble |
| 9 | A | A | 0.3009 | Aggregation-prone |
| 11 | E | A | 0.0377 | Aggregation-prone |
| 12 | V | A | 0.9961 | Aggregation-prone |
| 13 | K | A | -0.9126 | Soluble |
| 14 | K | A | -2.3321 | Soluble |
| 15 | P | A | -2.3611 | Soluble |
| 16 | G | A | -2.3442 | Soluble |
| 17 | A | A | -1.9406 | Soluble |
| 18 | S | A | -2.0484 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.0932 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6734 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.3783 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.0460 | Soluble |
| 27 | G | A | -1.0229 | Soluble |
| 28 | Y | A | -0.4711 | Soluble |
| 29 | P | A | -0.2641 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.2351 | Aggregation-prone |
| 36 | S | A | 0.3278 | Aggregation-prone |
| 37 | Y | A | 0.4335 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.5347 | Soluble |
| 45 | A | A | -0.8922 | Soluble |
| 46 | P | A | -0.7513 | Soluble |
| 47 | G | A | -1.2203 | Soluble |
| 48 | Q | A | -1.7266 | Soluble |
| 49 | G | A | -1.0843 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.5584 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.6087 | Aggregation-prone |
| 62 | N | A | -0.7392 | Soluble |
| 63 | G | A | -1.2729 | Soluble |
| 64 | N | A | -1.4629 | Soluble |
| 65 | T | A | -1.1380 | Soluble |
| 66 | N | A | -1.1221 | Soluble |
| 67 | Y | A | -1.0463 | Soluble |
| 68 | A | A | -1.5828 | Soluble |
| 69 | Q | A | -2.6175 | Soluble |
| 70 | K | A | -2.7352 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.5345 | Soluble |
| 74 | G | A | -1.8260 | Soluble |
| 75 | R | A | -2.1554 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.9007 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.4663 | Soluble |
| 80 | T | A | -0.6433 | Soluble |
| 81 | D | A | -1.1226 | Soluble |
| 82 | T | A | -0.4777 | Soluble |
| 83 | S | A | -0.5360 | Soluble |
| 84 | T | A | -0.6961 | Soluble |
| 85 | T | A | -0.8478 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.5734 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.6174 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -2.8443 | Soluble |
| 93 | R | A | -3.2298 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.2219 | Soluble |
| 96 | S | A | -2.1365 | Soluble |
| 97 | D | A | -2.3883 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.5988 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.3854 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.3107 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 0.7079 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.4904 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.5538 | Aggregation-prone |
| 111C | F | A | 1.6279 | Aggregation-prone |
| 112D | G | A | -0.2428 | Soluble |
| 112C | E | A | -1.4020 | Soluble |
| 112B | S | A | -0.7255 | Soluble |
| 112A | L | A | 0.5123 | Aggregation-prone |
| 112 | I | A | 1.7247 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.8020 | Soluble |
| 117 | N | A | -0.8495 | Soluble |
| 118 | W | A | -0.6763 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.2021 | Soluble |
| 121 | G | A | -0.4658 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.9603 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.0404 | Soluble |
| 128 | S | A | -0.7891 | Soluble |
| 129 | A | A | -0.5827 | Soluble |
| 130 | S | A | -0.6384 | Soluble |
| 131 | T | A | -0.7705 | Soluble |
| 132 | K | A | -1.6833 | Soluble |
| 133 | G | A | -1.5291 | Soluble |
| 134 | P | A | -0.7182 | Soluble |
| 135 | S | A | -0.5013 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | -0.7026 | Soluble |
| 138 | P | A | -0.9597 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.9040 | Soluble |
| 141 | P | A | -0.9289 | Soluble |
| 142 | S | A | -1.0743 | Soluble |
| 143 | S | A | -1.4737 | Soluble |
| 144 | K | A | -1.9005 | Soluble |
| 145 | T | A | -0.2737 | Soluble |
| 146 | A | A | -0.3749 | Soluble |
| 147 | A | A | 0.0000 | Buried |
| 148 | L | A | 0.0000 | Buried |
| 149 | G | A | 0.0000 | Buried |
| 150 | C | A | 0.0000 | Buried |
| 151 | L | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | K | A | -0.5597 | Soluble |
| 154 | D | A | -1.1773 | Soluble |
| 155 | Y | A | 0.0000 | Buried |
| 156 | F | A | 0.0000 | Buried |
| 157 | P | A | -0.8088 | Soluble |
| 158 | E | A | -0.6646 | Soluble |
| 159 | P | A | -0.9088 | Soluble |
| 160 | V | A | -0.5088 | Soluble |
| 161 | T | A | -0.5858 | Soluble |
| 162 | V | A | -0.3421 | Soluble |
| 163 | S | A | -0.4719 | Soluble |
| 164 | W | A | 0.0000 | Buried |
| 165 | N | A | -1.0880 | Soluble |
| 166 | S | A | -0.6140 | Soluble |
| 167 | G | A | -0.5646 | Soluble |
| 168 | A | A | -0.2999 | Soluble |
| 169 | L | A | -0.0042 | Soluble |
| 170 | T | A | -0.2410 | Soluble |
| 171 | S | A | -0.2345 | Soluble |
| 172 | G | A | -0.1727 | Soluble |
| 173 | V | A | 0.1870 | Aggregation-prone |
| 174 | H | A | -0.3536 | Soluble |
| 175 | T | A | 0.0361 | Aggregation-prone |
| 176 | F | A | 0.0000 | Buried |
| 177 | P | A | -0.2070 | Soluble |
| 178 | A | A | 0.1723 | Aggregation-prone |
| 179 | V | A | 0.4922 | Aggregation-prone |
| 180 | L | A | 1.0648 | Aggregation-prone |
| 181 | Q | A | 0.0079 | Aggregation-prone |
| 182 | S | A | -0.1260 | Soluble |
| 183 | S | A | -0.3569 | Soluble |
| 184 | G | A | -0.1605 | Soluble |
| 185 | L | A | 0.0000 | Buried |
| 186 | Y | A | 0.0000 | Buried |
| 187 | S | A | 0.0000 | Buried |
| 188 | L | A | 0.2708 | Aggregation-prone |
| 189 | S | A | 0.0000 | Buried |
| 190 | S | A | 0.0000 | Buried |
| 191 | V | A | 0.0000 | Buried |
| 192 | V | A | 0.0000 | Buried |
| 193 | T | A | -0.1623 | Soluble |
| 194 | V | A | 0.0000 | Buried |
| 195 | P | A | -0.5363 | Soluble |
| 196 | S | A | -0.6963 | Soluble |
| 197 | S | A | -0.5951 | Soluble |
| 198 | S | A | -0.6933 | Soluble |
| 199 | L | A | -0.9174 | Soluble |
| 200 | G | A | -1.3033 | Soluble |
| 201 | T | A | -0.9984 | Soluble |
| 202 | Q | A | -1.3859 | Soluble |
| 203 | T | A | -1.1813 | Soluble |
| 204 | Y | A | 0.0000 | Buried |
| 205 | I | A | -1.4231 | Soluble |
| 206 | C | A | 0.0000 | Buried |
| 207 | N | A | -1.8869 | Soluble |
| 208 | V | A | 0.0000 | Buried |
| 209 | N | A | -1.9067 | Soluble |
| 210 | H | A | 0.0000 | Buried |
| 211 | K | A | -2.6305 | Soluble |
| 212 | P | A | -1.7046 | Soluble |
| 213 | S | A | -1.9219 | Soluble |
| 214 | N | A | -2.4279 | Soluble |
| 215 | T | A | -2.1383 | Soluble |
| 216 | K | A | -2.6708 | Soluble |
| 217 | V | A | -1.7456 | Soluble |
| 218 | D | A | -2.7373 | Soluble |
| 219 | K | A | -2.0637 | Soluble |
| 220 | K | A | -2.4405 | Soluble |
| 221 | V | A | 0.0000 | Buried |
| 222 | E | A | -2.7638 | Soluble |
| 223 | P | A | -1.9670 | Soluble |
| 224 | K | A | -2.3205 | Soluble |
| 1 | E | B | -1.5835 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.7471 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.7803 | Soluble |
| 6 | Q | B | -1.0332 | Soluble |
| 7 | S | B | -0.9103 | Soluble |
| 8 | P | B | -0.6901 | Soluble |
| 9 | G | B | -0.8690 | Soluble |
| 10 | T | B | -0.5937 | Soluble |
| 11 | L | B | -0.4163 | Soluble |
| 12 | S | B | -0.7346 | Soluble |
| 13 | L | B | -1.2958 | Soluble |
| 14 | S | B | -1.8669 | Soluble |
| 15 | P | B | -2.0332 | Soluble |
| 16 | G | B | -2.4372 | Soluble |
| 17 | E | B | -3.5297 | Soluble |
| 18 | R | B | -3.4781 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.5363 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -1.0430 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.5444 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -1.0402 | Soluble |
| 27 | Q | B | -1.5147 | Soluble |
| 28 | T | B | -1.3398 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6568 | Soluble |
| 36 | S | B | -0.3208 | Soluble |
| 37 | T | B | 0.1616 | Aggregation-prone |
| 38 | S | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.3026 | Soluble |
| 46 | P | B | -1.1478 | Soluble |
| 47 | G | B | -1.2465 | Soluble |
| 48 | Q | B | -1.9333 | Soluble |
| 49 | A | B | -1.2872 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.2238 | Soluble |
| 52 | L | B | -0.6464 | Soluble |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.2348 | Aggregation-prone |
| 56 | G | B | 0.2097 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.5979 | Soluble |
| 66 | S | B | -0.4903 | Soluble |
| 67 | R | B | -1.3089 | Soluble |
| 68 | A | B | -0.7143 | Soluble |
| 69 | T | B | -0.5447 | Soluble |
| 70 | G | B | -0.7595 | Soluble |
| 71 | I | B | -0.7597 | Soluble |
| 72 | P | B | -1.2117 | Soluble |
| 74 | D | B | -2.1728 | Soluble |
| 75 | R | B | -1.8442 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.9217 | Soluble |
| 78 | G | B | -0.5013 | Soluble |
| 79 | S | B | -0.7496 | Soluble |
| 80 | G | B | -1.2056 | Soluble |
| 83 | S | B | -1.1975 | Soluble |
| 84 | G | B | -1.2632 | Soluble |
| 85 | T | B | -1.8754 | Soluble |
| 86 | D | B | -2.5471 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.8903 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8073 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.4979 | Soluble |
| 93 | R | B | -3.4879 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.3099 | Soluble |
| 96 | P | B | -1.5023 | Soluble |
| 97 | E | B | -2.0352 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.7277 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.3361 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | D | B | -1.0710 | Soluble |
| 114 | T | B | -1.0767 | Soluble |
| 115 | S | B | -0.7674 | Soluble |
| 116 | L | B | -0.2158 | Soluble |
| 117 | T | B | -0.0612 | Soluble |
| 118 | F | B | 0.2237 | Aggregation-prone |
| 119 | G | B | -0.2717 | Soluble |
| 120 | G | B | -0.6425 | Soluble |
| 121 | G | B | -0.8140 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.8955 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -0.6991 | Soluble |
| 126 | I | B | -0.8909 | Soluble |
| 127 | K | B | -1.7965 | Soluble |
| 128 | R | B | -1.3731 | Soluble |
| 129 | T | B | -0.0976 | Soluble |
| 130 | V | B | 1.0668 | Aggregation-prone |
| 131 | A | B | 0.4812 | Aggregation-prone |
| 132 | A | B | 0.0681 | Aggregation-prone |
| 133 | P | B | -0.1595 | Soluble |
| 134 | S | B | -0.0933 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.4813 | Aggregation-prone |
| 137 | I | B | 0.3270 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.6778 | Soluble |
| 140 | P | B | -0.8580 | Soluble |
| 141 | S | B | -1.3657 | Soluble |
| 142 | D | B | -2.7288 | Soluble |
| 143 | E | B | -2.9344 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.1624 | Soluble |
| 146 | K | B | -2.5944 | Soluble |
| 147 | S | B | -1.7380 | Soluble |
| 148 | G | B | -1.0698 | Soluble |
| 149 | T | B | -0.9390 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | -0.3508 | Soluble |
| 158 | N | B | -0.7723 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.2012 | Soluble |
| 162 | R | B | -2.0899 | Soluble |
| 163 | E | B | -2.6952 | Soluble |
| 164 | A | B | -2.0285 | Soluble |
| 165 | K | B | -2.2186 | Soluble |
| 166 | V | B | -1.1301 | Soluble |
| 167 | Q | B | -0.6675 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -1.0519 | Soluble |
| 170 | V | B | -1.2958 | Soluble |
| 171 | D | B | -2.5470 | Soluble |
| 172 | N | B | -1.8880 | Soluble |
| 173 | A | B | -0.5612 | Soluble |
| 174 | L | B | 0.4399 | Aggregation-prone |
| 175 | Q | B | -0.6340 | Soluble |
| 176 | S | B | -1.0651 | Soluble |
| 177 | G | B | -1.5410 | Soluble |
| 178 | N | B | -1.9251 | Soluble |
| 179 | S | B | -1.8785 | Soluble |
| 180 | Q | B | -2.1203 | Soluble |
| 181 | E | B | -1.8344 | Soluble |
| 182 | S | B | -0.6415 | Soluble |
| 183 | V | B | -0.3580 | Soluble |
| 184 | T | B | -0.9118 | Soluble |
| 185 | E | B | -2.1019 | Soluble |
| 186 | Q | B | -1.7656 | Soluble |
| 187 | D | B | -1.9547 | Soluble |
| 188 | S | B | -1.7800 | Soluble |
| 189 | K | B | -2.2737 | Soluble |
| 190 | D | B | -1.8116 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.9090 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.5150 | Soluble |
| 201 | L | B | -0.6205 | Soluble |
| 202 | S | B | -1.1367 | Soluble |
| 203 | K | B | -2.3568 | Soluble |
| 204 | A | B | -2.2476 | Soluble |
| 205 | D | B | -3.3490 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.9934 | Soluble |
| 208 | K | B | -3.9045 | Soluble |
| 209 | H | B | -3.4100 | Soluble |
| 210 | K | B | -3.1569 | Soluble |
| 211 | V | B | -2.0024 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.6471 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1101 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5709 | Soluble |
| 220 | G | B | -0.2374 | Soluble |
| 221 | L | B | -0.1105 | Soluble |
| 222 | S | B | -0.4373 | Soluble |
| 223 | S | B | -0.4201 | Soluble |
| 224 | P | B | -0.5078 | Soluble |
| 225 | V | B | 0.0089 | Aggregation-prone |
| 226 | T | B | -0.4987 | Soluble |
| 227 | K | B | -0.6827 | Soluble |
| 228 | S | B | -0.9355 | Soluble |
| 229 | F | B | -1.1105 | Soluble |
| 230 | N | B | -2.1844 | Soluble |
| 231 | R | B | -2.0787 | Soluble |
| 232 | G | B | -1.2221 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7063 | 5.2431 | CSV PDB |
| 4.5 | -0.7505 | 5.1735 | CSV PDB |
| 5.0 | -0.8035 | 5.0656 | CSV PDB |
| 5.5 | -0.8543 | 4.9365 | CSV PDB |
| 6.0 | -0.8906 | 4.8614 | CSV PDB |
| 6.5 | -0.9036 | 4.8069 | CSV PDB |
| 7.0 | -0.8929 | 4.771 | CSV PDB |
| 7.5 | -0.8664 | 4.7537 | CSV PDB |
| 8.0 | -0.8313 | 4.747 | CSV PDB |
| 8.5 | -0.7903 | 4.7446 | CSV PDB |
| 9.0 | -0.7431 | 4.7434 | CSV PDB |