Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKEIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLEPEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.2909 | Soluble |
| 2 | V | A | -0.7731 | Soluble |
| 3 | Q | A | -1.6648 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | -0.7998 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.7448 | Soluble |
| 8 | G | A | -0.4272 | Soluble |
| 9 | A | A | -0.0459 | Soluble |
| 11 | E | A | -0.3957 | Soluble |
| 12 | V | A | -0.0664 | Soluble |
| 13 | K | A | -1.3933 | Soluble |
| 14 | K | A | -2.4903 | Soluble |
| 15 | P | A | -2.4470 | Soluble |
| 16 | G | A | -2.2193 | Soluble |
| 17 | A | A | -1.6827 | Soluble |
| 18 | S | A | -1.8821 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -1.9180 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.6964 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -1.6710 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.9446 | Soluble |
| 27 | G | A | -0.6985 | Soluble |
| 28 | Y | A | -0.3247 | Soluble |
| 29 | P | A | -0.1951 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | T | A | 0.1858 | Aggregation-prone |
| 36 | S | A | 0.3532 | Aggregation-prone |
| 37 | Y | A | 0.5086 | Aggregation-prone |
| 38 | G | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.5384 | Soluble |
| 45 | A | A | -0.9207 | Soluble |
| 46 | P | A | -0.9507 | Soluble |
| 47 | G | A | -1.2445 | Soluble |
| 48 | Q | A | -1.7207 | Soluble |
| 49 | G | A | -1.0641 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.5553 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | W | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | S | A | 0.0000 | Buried |
| 58 | T | A | 0.0000 | Buried |
| 59 | Y | A | 0.7589 | Aggregation-prone |
| 62 | N | A | -0.4427 | Soluble |
| 63 | G | A | -1.0826 | Soluble |
| 64 | N | A | -1.4198 | Soluble |
| 65 | T | A | -1.2495 | Soluble |
| 66 | N | A | -1.4007 | Soluble |
| 67 | Y | A | -1.2360 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | Q | A | -2.5697 | Soluble |
| 70 | K | A | -2.6829 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.4438 | Soluble |
| 74 | G | A | -1.8390 | Soluble |
| 75 | R | A | -1.6888 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.7069 | Soluble |
| 78 | M | A | 0.0000 | Buried |
| 79 | T | A | -0.3798 | Soluble |
| 80 | T | A | -0.5827 | Soluble |
| 81 | D | A | -0.9913 | Soluble |
| 82 | T | A | -0.4555 | Soluble |
| 83 | S | A | -0.5350 | Soluble |
| 84 | T | A | -0.7575 | Soluble |
| 85 | T | A | -0.8441 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | G | A | 0.0000 | Buried |
| 88 | Y | A | -0.4202 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.1523 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | R | A | -2.1834 | Soluble |
| 93 | R | A | -2.9908 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -3.4758 | Soluble |
| 96 | S | A | -2.5995 | Soluble |
| 97 | D | A | -2.5276 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.9126 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2876 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.2794 | Soluble |
| 107 | D | A | 0.0000 | Buried |
| 108 | Y | A | 1.0330 | Aggregation-prone |
| 109 | T | A | 0.0000 | Buried |
| 110 | R | A | -0.0906 | Soluble |
| 111 | G | A | 0.0000 | Buried |
| 111A | A | A | 0.0000 | Buried |
| 111B | W | A | 1.6348 | Aggregation-prone |
| 111C | F | A | 1.6062 | Aggregation-prone |
| 112D | G | A | -0.4391 | Soluble |
| 112C | E | A | -1.3505 | Soluble |
| 112B | S | A | -0.5450 | Soluble |
| 112A | L | A | 0.6666 | Aggregation-prone |
| 112 | I | A | 2.2326 | Aggregation-prone |
| 113 | G | A | 0.0000 | Buried |
| 114 | G | A | 0.0000 | Buried |
| 115 | F | A | 0.0000 | Buried |
| 116 | D | A | -0.5987 | Soluble |
| 117 | N | A | -0.9584 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.3746 | Soluble |
| 121 | G | A | -0.5370 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | L | A | 0.5797 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | 0.0000 | Buried |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.3568 | Soluble |
| 128 | S | A | -1.1567 | Soluble |
| 129 | A | A | -0.6466 | Soluble |
| 130 | S | A | -0.6860 | Soluble |
| 131 | T | A | -0.7236 | Soluble |
| 132 | K | A | -1.1922 | Soluble |
| 133 | G | A | -1.3723 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.2861 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.0798 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.1684 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -1.2707 | Soluble |
| 143 | S | A | -1.3661 | Soluble |
| 144 | K | A | -1.7860 | Soluble |
| 145 | G | A | -0.6367 | Soluble |
| 146 | T | A | -0.4681 | Soluble |
| 147 | A | A | -0.4854 | Soluble |
| 148 | A | A | 0.0000 | Buried |
| 149 | L | A | 0.0000 | Buried |
| 150 | G | A | 0.0000 | Buried |
| 151 | C | A | 0.0000 | Buried |
| 152 | L | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | K | A | -0.3264 | Soluble |
| 155 | D | A | -0.4496 | Soluble |
| 156 | Y | A | 0.0000 | Buried |
| 157 | F | A | 0.0000 | Buried |
| 158 | P | A | 0.0000 | Buried |
| 159 | E | A | -0.6260 | Soluble |
| 160 | P | A | -0.9441 | Soluble |
| 161 | V | A | -0.7740 | Soluble |
| 162 | T | A | -0.5929 | Soluble |
| 163 | V | A | -0.2227 | Soluble |
| 164 | S | A | -0.4213 | Soluble |
| 165 | W | A | 0.0000 | Buried |
| 166 | N | A | -0.7353 | Soluble |
| 167 | S | A | -0.6782 | Soluble |
| 168 | G | A | -0.5628 | Soluble |
| 169 | A | A | -0.2318 | Soluble |
| 170 | L | A | -0.0057 | Soluble |
| 171 | T | A | -0.1684 | Soluble |
| 172 | S | A | -0.1730 | Soluble |
| 173 | G | A | -0.1844 | Soluble |
| 174 | V | A | 0.1587 | Aggregation-prone |
| 175 | H | A | -0.2876 | Soluble |
| 176 | T | A | 0.0541 | Aggregation-prone |
| 177 | F | A | 0.0000 | Buried |
| 178 | P | A | -0.2170 | Soluble |
| 179 | A | A | 0.2322 | Aggregation-prone |
| 180 | V | A | 0.6222 | Aggregation-prone |
| 181 | L | A | 1.3093 | Aggregation-prone |
| 182 | Q | A | 0.3086 | Aggregation-prone |
| 183 | S | A | -0.1104 | Soluble |
| 184 | S | A | -0.1756 | Soluble |
| 185 | G | A | 0.0662 | Aggregation-prone |
| 186 | L | A | 0.0781 | Aggregation-prone |
| 187 | Y | A | 0.3451 | Aggregation-prone |
| 188 | S | A | 0.0000 | Buried |
| 189 | L | A | 0.0000 | Buried |
| 190 | S | A | 0.0000 | Buried |
| 191 | S | A | 0.0000 | Buried |
| 192 | V | A | 0.0000 | Buried |
| 193 | V | A | 0.0000 | Buried |
| 194 | T | A | -0.1344 | Soluble |
| 195 | V | A | 0.0000 | Buried |
| 196 | P | A | -0.5982 | Soluble |
| 197 | S | A | -0.5548 | Soluble |
| 198 | S | A | -0.6419 | Soluble |
| 199 | S | A | -0.6365 | Soluble |
| 200 | L | A | -0.8647 | Soluble |
| 201 | G | A | -1.0111 | Soluble |
| 202 | T | A | -0.9045 | Soluble |
| 203 | Q | A | -1.2245 | Soluble |
| 204 | T | A | -1.1389 | Soluble |
| 205 | Y | A | 0.0000 | Buried |
| 206 | I | A | -1.4276 | Soluble |
| 207 | C | A | 0.0000 | Buried |
| 208 | N | A | -1.5611 | Soluble |
| 209 | V | A | 0.0000 | Buried |
| 210 | N | A | -2.0006 | Soluble |
| 211 | H | A | 0.0000 | Buried |
| 212 | K | A | -2.8769 | Soluble |
| 213 | P | A | -1.7402 | Soluble |
| 214 | S | A | -1.8756 | Soluble |
| 215 | N | A | -2.7087 | Soluble |
| 216 | T | A | -2.1344 | Soluble |
| 217 | K | A | -2.6920 | Soluble |
| 218 | V | A | -1.6422 | Soluble |
| 219 | D | A | -2.5876 | Soluble |
| 220 | K | A | -2.1127 | Soluble |
| 221 | K | A | -2.6342 | Soluble |
| 222 | V | A | 0.0000 | Buried |
| 223 | E | A | -2.8289 | Soluble |
| 224 | P | A | -1.8980 | Soluble |
| 225 | K | A | -2.0778 | Soluble |
| 1 | E | B | -1.5813 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | V | B | 0.5784 | Aggregation-prone |
| 4 | L | B | 0.0000 | Buried |
| 5 | T | B | -0.7007 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.8876 | Soluble |
| 8 | P | B | -0.6423 | Soluble |
| 9 | G | B | -0.8490 | Soluble |
| 10 | T | B | -0.4879 | Soluble |
| 11 | L | B | -0.2728 | Soluble |
| 12 | S | B | -0.5993 | Soluble |
| 13 | L | B | -0.9768 | Soluble |
| 14 | S | B | -1.5960 | Soluble |
| 15 | P | B | -1.9170 | Soluble |
| 16 | G | B | -2.1918 | Soluble |
| 17 | E | B | -2.7305 | Soluble |
| 18 | R | B | -3.0773 | Soluble |
| 19 | A | B | 0.0000 | Buried |
| 20 | T | B | -0.6010 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -1.0476 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.5425 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -1.1201 | Soluble |
| 27 | Q | B | -1.8423 | Soluble |
| 28 | T | B | -1.4244 | Soluble |
| 29 | V | B | 0.0000 | Buried |
| 30 | S | B | -0.6775 | Soluble |
| 36 | S | B | -0.2390 | Soluble |
| 37 | T | B | 0.3605 | Aggregation-prone |
| 38 | S | B | 0.0000 | Buried |
| 39 | L | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | -0.6307 | Soluble |
| 44 | Q | B | -0.8968 | Soluble |
| 45 | K | B | -1.3375 | Soluble |
| 46 | P | B | -1.2158 | Soluble |
| 47 | G | B | -1.1683 | Soluble |
| 48 | Q | B | -1.4809 | Soluble |
| 49 | A | B | 0.0000 | Buried |
| 50 | P | B | 0.0000 | Buried |
| 51 | R | B | -1.2060 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.4198 | Aggregation-prone |
| 56 | G | B | 0.4095 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.6485 | Soluble |
| 66 | S | B | -0.4926 | Soluble |
| 67 | R | B | -1.5164 | Soluble |
| 68 | A | B | -0.7858 | Soluble |
| 69 | T | B | -0.5636 | Soluble |
| 70 | G | B | -0.7835 | Soluble |
| 71 | I | B | -0.8959 | Soluble |
| 72 | P | B | -1.2627 | Soluble |
| 74 | D | B | -2.1962 | Soluble |
| 75 | R | B | -2.0076 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.9305 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -0.7495 | Soluble |
| 80 | G | B | -1.2816 | Soluble |
| 83 | S | B | -1.2604 | Soluble |
| 84 | G | B | -1.3548 | Soluble |
| 85 | T | B | -2.0271 | Soluble |
| 86 | D | B | -2.8436 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.9151 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.8135 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -2.4077 | Soluble |
| 93 | R | B | -3.3262 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | E | B | -2.4822 | Soluble |
| 96 | P | B | -1.8549 | Soluble |
| 97 | E | B | -2.3186 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.7582 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | -0.4000 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | D | B | -1.1658 | Soluble |
| 114 | T | B | -1.0759 | Soluble |
| 115 | S | B | -0.9444 | Soluble |
| 116 | L | B | 0.0000 | Buried |
| 117 | T | B | -0.1004 | Soluble |
| 118 | F | B | 0.2535 | Aggregation-prone |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -0.7419 | Soluble |
| 121 | G | B | -0.7880 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -0.8810 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | 0.0000 | Buried |
| 126 | I | B | -0.9551 | Soluble |
| 127 | K | B | -1.6605 | Soluble |
| 128 | R | B | -1.1286 | Soluble |
| 129 | T | B | -0.1290 | Soluble |
| 130 | V | B | 0.4650 | Aggregation-prone |
| 131 | A | B | 0.1147 | Aggregation-prone |
| 132 | A | B | -0.0996 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.0932 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.1483 | Aggregation-prone |
| 137 | I | B | 0.0950 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4839 | Soluble |
| 140 | P | B | -0.8297 | Soluble |
| 141 | S | B | -1.7116 | Soluble |
| 142 | D | B | -2.8076 | Soluble |
| 143 | E | B | -2.6925 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.2463 | Soluble |
| 146 | K | B | -2.7890 | Soluble |
| 147 | S | B | -1.7312 | Soluble |
| 148 | G | B | -1.2590 | Soluble |
| 149 | T | B | -0.9994 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.7914 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.2255 | Soluble |
| 162 | R | B | -1.6674 | Soluble |
| 163 | E | B | -2.5746 | Soluble |
| 164 | A | B | -1.8784 | Soluble |
| 165 | K | B | -1.9730 | Soluble |
| 166 | V | B | -0.9572 | Soluble |
| 167 | Q | B | -0.7202 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.7770 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.9470 | Soluble |
| 172 | N | B | -1.6054 | Soluble |
| 173 | A | B | -0.4293 | Soluble |
| 174 | L | B | 0.3705 | Aggregation-prone |
| 175 | Q | B | -0.2731 | Soluble |
| 176 | S | B | -0.4944 | Soluble |
| 177 | G | B | -0.8724 | Soluble |
| 178 | N | B | -0.8215 | Soluble |
| 179 | S | B | -1.0002 | Soluble |
| 180 | Q | B | -1.0221 | Soluble |
| 181 | E | B | -1.3902 | Soluble |
| 182 | S | B | -0.4712 | Soluble |
| 183 | V | B | -0.3469 | Soluble |
| 184 | T | B | -0.9750 | Soluble |
| 185 | E | B | -2.1405 | Soluble |
| 186 | Q | B | -1.8269 | Soluble |
| 187 | D | B | -2.1716 | Soluble |
| 188 | S | B | -2.0390 | Soluble |
| 189 | K | B | -2.3864 | Soluble |
| 190 | D | B | -1.9613 | Soluble |
| 191 | S | B | -1.9119 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.4885 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4172 | Soluble |
| 201 | L | B | -0.6273 | Soluble |
| 202 | S | B | -1.1946 | Soluble |
| 203 | K | B | -2.0988 | Soluble |
| 204 | A | B | -1.7895 | Soluble |
| 205 | D | B | -2.2390 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.2038 | Soluble |
| 208 | K | B | -3.4393 | Soluble |
| 209 | H | B | -2.7774 | Soluble |
| 210 | K | B | -2.9682 | Soluble |
| 211 | V | B | -1.3725 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.7817 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.9149 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.1089 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.5520 | Soluble |
| 220 | G | B | -0.4083 | Soluble |
| 221 | L | B | -0.2338 | Soluble |
| 222 | S | B | -0.4444 | Soluble |
| 223 | S | B | -0.4154 | Soluble |
| 224 | P | B | -0.5111 | Soluble |
| 225 | V | B | -0.0720 | Soluble |
| 226 | T | B | -0.4913 | Soluble |
| 227 | K | B | -0.6295 | Soluble |
| 228 | S | B | -0.4366 | Soluble |
| 229 | F | B | -0.6862 | Soluble |
| 230 | N | B | -1.5515 | Soluble |
| 231 | R | B | -2.2527 | Soluble |
| 232 | G | B | -1.8615 | Soluble |
| 233 | E | B | -2.0289 | Soluble |
| 234 | C | B | -1.0034 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7064 | 5.3694 | CSV PDB |
| 4.5 | -0.7499 | 5.279 | CSV PDB |
| 5.0 | -0.8 | 5.1547 | CSV PDB |
| 5.5 | -0.8466 | 5.0869 | CSV PDB |
| 6.0 | -0.8784 | 5.026 | CSV PDB |
| 6.5 | -0.8869 | 4.979 | CSV PDB |
| 7.0 | -0.8727 | 4.9519 | CSV PDB |
| 7.5 | -0.8431 | 4.9402 | CSV PDB |
| 8.0 | -0.8044 | 4.936 | CSV PDB |
| 8.5 | -0.7583 | 4.9344 | CSV PDB |
| 9.0 | -0.7054 | 4.9335 | CSV PDB |