Calculation Parameters
| Chain Sequence(s) |
QVQLVQSGAEVKKPGSSVKVSCKASGGTFSNYAISWVRQAPGQGLEWMGRIIPILGIANYAQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCARGYYEARHYYYYYAMDVWGQGTAVTVSSASTKGPSVFPLAPCSSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVHHHHHDIQMTQSPSSLSASVGDRVTITCRASQSISSYLSWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTITSLQPEDFATYYCQQSYSTPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | A | -1.4436 | Soluble |
| 2 | V | A | -0.8997 | Soluble |
| 3 | Q | A | -1.4471 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.1406 | Aggregation-prone |
| 6 | Q | A | 0.0000 | Buried |
| 7 | S | A | -0.6005 | Soluble |
| 8 | G | A | -0.5489 | Soluble |
| 9 | A | A | -0.2493 | Soluble |
| 11 | E | A | -0.5801 | Soluble |
| 12 | V | A | 0.1148 | Aggregation-prone |
| 13 | K | A | -1.1997 | Soluble |
| 14 | K | A | -2.2270 | Soluble |
| 15 | P | A | -2.1264 | Soluble |
| 16 | G | A | -1.5165 | Soluble |
| 17 | S | A | -1.1971 | Soluble |
| 18 | S | A | -1.3430 | Soluble |
| 19 | V | A | 0.0000 | Buried |
| 20 | K | A | -2.0444 | Soluble |
| 21 | V | A | 0.0000 | Buried |
| 22 | S | A | -0.4589 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | K | A | -0.7371 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -0.8261 | Soluble |
| 27 | G | A | -1.1703 | Soluble |
| 28 | G | A | -0.9090 | Soluble |
| 29 | T | A | -0.7171 | Soluble |
| 30 | F | A | 0.0000 | Buried |
| 35 | S | A | -0.3622 | Soluble |
| 36 | N | A | -0.6676 | Soluble |
| 37 | Y | A | -0.1556 | Soluble |
| 38 | A | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | S | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | -0.4512 | Soluble |
| 44 | Q | A | -0.6847 | Soluble |
| 45 | A | A | -1.0382 | Soluble |
| 46 | P | A | -1.0482 | Soluble |
| 47 | G | A | -1.2220 | Soluble |
| 48 | Q | A | -1.8551 | Soluble |
| 49 | G | A | -1.3582 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -0.8109 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | M | A | 0.0000 | Buried |
| 54 | G | A | 0.0000 | Buried |
| 55 | R | A | -0.4707 | Soluble |
| 56 | I | A | 0.0000 | Buried |
| 57 | I | A | 0.0000 | Buried |
| 58 | P | A | 0.0000 | Buried |
| 59 | I | A | 1.3254 | Aggregation-prone |
| 62 | L | A | 2.0120 | Aggregation-prone |
| 63 | G | A | 0.7925 | Aggregation-prone |
| 64 | I | A | 1.2657 | Aggregation-prone |
| 65 | A | A | -0.0113 | Soluble |
| 66 | N | A | -1.2523 | Soluble |
| 67 | Y | A | -1.4438 | Soluble |
| 68 | A | A | 0.0000 | Buried |
| 69 | Q | A | -2.5072 | Soluble |
| 70 | K | A | -2.5803 | Soluble |
| 71 | F | A | 0.0000 | Buried |
| 72 | Q | A | -2.4893 | Soluble |
| 74 | G | A | -1.6348 | Soluble |
| 75 | R | A | -1.4091 | Soluble |
| 76 | V | A | 0.0000 | Buried |
| 77 | T | A | -0.9644 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | T | A | -0.3757 | Soluble |
| 80 | A | A | -0.5649 | Soluble |
| 81 | D | A | -1.7842 | Soluble |
| 82 | K | A | -1.9561 | Soluble |
| 83 | S | A | -1.3478 | Soluble |
| 84 | T | A | -1.0837 | Soluble |
| 85 | S | A | 0.0000 | Buried |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | -0.4631 | Soluble |
| 89 | M | A | 0.0000 | Buried |
| 90 | E | A | -1.4592 | Soluble |
| 91 | L | A | 0.0000 | Buried |
| 92 | S | A | -1.1030 | Soluble |
| 93 | S | A | -1.1006 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.7913 | Soluble |
| 96 | S | A | -2.2615 | Soluble |
| 97 | E | A | -2.4775 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.9454 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.0531 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | R | A | -0.2706 | Soluble |
| 107 | G | A | 0.0000 | Buried |
| 108 | Y | A | 0.0000 | Buried |
| 109 | Y | A | -0.0868 | Soluble |
| 110 | E | A | -0.8399 | Soluble |
| 111 | A | A | -0.5807 | Soluble |
| 111A | R | A | -1.5818 | Soluble |
| 111B | H | A | -0.2775 | Soluble |
| 112C | Y | A | 1.0209 | Aggregation-prone |
| 112B | Y | A | 1.5732 | Aggregation-prone |
| 112A | Y | A | 1.0339 | Aggregation-prone |
| 112 | Y | A | 1.3905 | Aggregation-prone |
| 113 | Y | A | 0.9091 | Aggregation-prone |
| 114 | A | A | 0.0000 | Buried |
| 115 | M | A | 0.0000 | Buried |
| 116 | D | A | -0.4098 | Soluble |
| 117 | V | A | -0.5930 | Soluble |
| 118 | W | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4935 | Soluble |
| 121 | G | A | -0.8182 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | A | A | -0.1905 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.6474 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -1.2378 | Soluble |
| 128 | S | A | -1.0855 | Soluble |
| 129 | A | A | -0.6180 | Soluble |
| 130 | S | A | -0.6655 | Soluble |
| 131 | T | A | -0.7605 | Soluble |
| 132 | K | A | -1.5144 | Soluble |
| 133 | G | A | -1.6520 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.3591 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.3307 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | 0.0000 | Buried |
| 141 | P | A | -0.4502 | Soluble |
| 142 | C | A | -0.4835 | Soluble |
| 143 | S | A | -0.6715 | Soluble |
| 144 | S | A | -1.2256 | Soluble |
| 145 | E | A | -2.1299 | Soluble |
| 146 | S | A | -1.2831 | Soluble |
| 147 | T | A | -0.9132 | Soluble |
| 148 | A | A | -0.7538 | Soluble |
| 149 | A | A | 0.0000 | Buried |
| 150 | L | A | 0.0000 | Buried |
| 151 | G | A | 0.0000 | Buried |
| 152 | C | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | V | A | 0.0000 | Buried |
| 155 | K | A | 0.0000 | Buried |
| 156 | D | A | -0.6201 | Soluble |
| 157 | Y | A | 0.0000 | Buried |
| 158 | F | A | 0.0000 | Buried |
| 159 | P | A | 0.0000 | Buried |
| 160 | E | A | -1.1339 | Soluble |
| 161 | P | A | -1.3447 | Soluble |
| 162 | V | A | -1.1935 | Soluble |
| 163 | T | A | -0.9478 | Soluble |
| 164 | V | A | -0.5966 | Soluble |
| 165 | S | A | -0.6037 | Soluble |
| 166 | W | A | 0.0000 | Buried |
| 167 | N | A | -0.9326 | Soluble |
| 168 | S | A | -0.7634 | Soluble |
| 169 | G | A | -0.6005 | Soluble |
| 170 | A | A | -0.2838 | Soluble |
| 171 | L | A | -0.1011 | Soluble |
| 172 | T | A | -0.1792 | Soluble |
| 173 | S | A | -0.3298 | Soluble |
| 174 | G | A | -0.1113 | Soluble |
| 175 | V | A | 0.1912 | Aggregation-prone |
| 176 | H | A | -0.2753 | Soluble |
| 177 | T | A | 0.0256 | Aggregation-prone |
| 178 | F | A | 0.0000 | Buried |
| 179 | P | A | -0.4097 | Soluble |
| 180 | A | A | -0.0581 | Soluble |
| 181 | V | A | 0.2731 | Aggregation-prone |
| 182 | L | A | 0.9057 | Aggregation-prone |
| 183 | Q | A | 0.1668 | Aggregation-prone |
| 184 | S | A | -0.1204 | Soluble |
| 185 | S | A | -0.2344 | Soluble |
| 186 | G | A | -0.0610 | Soluble |
| 187 | L | A | -0.1729 | Soluble |
| 188 | Y | A | 0.0000 | Buried |
| 189 | S | A | 0.0163 | Aggregation-prone |
| 190 | L | A | 0.0000 | Buried |
| 191 | S | A | 0.0000 | Buried |
| 192 | S | A | 0.0000 | Buried |
| 193 | V | A | 0.0000 | Buried |
| 194 | V | A | 0.0000 | Buried |
| 195 | T | A | -0.0947 | Soluble |
| 196 | V | A | 0.0000 | Buried |
| 197 | P | A | -0.6505 | Soluble |
| 198 | S | A | -0.8793 | Soluble |
| 199 | S | A | -0.7672 | Soluble |
| 200 | S | A | -0.5868 | Soluble |
| 201 | L | A | -0.7892 | Soluble |
| 202 | G | A | -0.8151 | Soluble |
| 203 | T | A | -0.7530 | Soluble |
| 204 | K | A | -1.1687 | Soluble |
| 205 | T | A | -1.2175 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | T | A | 0.0000 | Buried |
| 208 | C | A | 0.0000 | Buried |
| 209 | N | A | -1.8402 | Soluble |
| 210 | V | A | 0.0000 | Buried |
| 211 | D | A | -2.8081 | Soluble |
| 212 | H | A | 0.0000 | Buried |
| 213 | K | A | -3.0676 | Soluble |
| 214 | P | A | -1.8690 | Soluble |
| 215 | S | A | -1.9872 | Soluble |
| 216 | N | A | -2.7254 | Soluble |
| 217 | T | A | -2.3273 | Soluble |
| 218 | K | A | -3.0361 | Soluble |
| 219 | V | A | -1.7582 | Soluble |
| 220 | D | A | -2.8372 | Soluble |
| 221 | K | A | -2.1582 | Soluble |
| 222 | R | A | -2.7697 | Soluble |
| 223 | V | A | 0.0000 | Buried |
| 224 | H | A | -2.1175 | Soluble |
| 225 | H | A | -1.7985 | Soluble |
| 226 | H | A | -1.4584 | Soluble |
| 227 | H | A | -1.4151 | Soluble |
| 228 | H | A | -1.9336 | Soluble |
| 1 | D | B | -2.3544 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | Q | B | -2.1585 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -1.4057 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.8783 | Soluble |
| 8 | P | B | -0.5193 | Soluble |
| 9 | S | B | -0.8420 | Soluble |
| 10 | S | B | -0.8556 | Soluble |
| 11 | L | B | -0.6182 | Soluble |
| 12 | S | B | -0.9847 | Soluble |
| 13 | A | B | 0.0000 | Buried |
| 14 | S | B | -0.4412 | Soluble |
| 15 | V | B | 0.5015 | Aggregation-prone |
| 16 | G | B | -0.5404 | Soluble |
| 17 | D | B | -1.3590 | Soluble |
| 18 | R | B | -2.1423 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.5872 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.7985 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.6575 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -1.7851 | Soluble |
| 27 | Q | B | -1.6912 | Soluble |
| 28 | S | B | -0.9957 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 36 | S | B | -0.3143 | Soluble |
| 37 | S | B | 0.1278 | Aggregation-prone |
| 38 | Y | B | 0.6894 | Aggregation-prone |
| 39 | L | B | 0.0000 | Buried |
| 40 | S | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.7337 | Soluble |
| 46 | P | B | -1.4627 | Soluble |
| 47 | G | B | -1.6398 | Soluble |
| 48 | K | B | -2.6194 | Soluble |
| 49 | A | B | -1.7297 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.7692 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 0.4952 | Aggregation-prone |
| 56 | A | B | 0.5813 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.2533 | Soluble |
| 66 | S | B | 0.2262 | Aggregation-prone |
| 67 | L | B | 0.2887 | Aggregation-prone |
| 68 | Q | B | -0.2428 | Soluble |
| 69 | S | B | -0.3637 | Soluble |
| 70 | G | B | -0.4735 | Soluble |
| 71 | V | B | -0.3347 | Soluble |
| 72 | P | B | -0.3129 | Soluble |
| 74 | S | B | -0.4134 | Soluble |
| 75 | R | B | -0.7447 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.2797 | Soluble |
| 78 | G | B | -0.2648 | Soluble |
| 79 | S | B | -0.6330 | Soluble |
| 80 | G | B | -1.0488 | Soluble |
| 83 | S | B | -1.0131 | Soluble |
| 84 | G | B | -1.1843 | Soluble |
| 85 | T | B | -1.6181 | Soluble |
| 86 | D | B | -1.9283 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7157 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6123 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | T | B | -1.3228 | Soluble |
| 93 | S | B | -0.9412 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -0.7499 | Soluble |
| 96 | P | B | -0.8741 | Soluble |
| 97 | E | B | -1.8772 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | -0.6354 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | 0.0000 | Buried |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | S | B | 0.0000 | Buried |
| 108 | Y | B | 0.8208 | Aggregation-prone |
| 109 | S | B | -0.0802 | Soluble |
| 114 | T | B | -0.6392 | Soluble |
| 115 | P | B | 0.0000 | Buried |
| 116 | R | B | -0.5235 | Soluble |
| 117 | T | B | -0.8353 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.4086 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.5002 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.3837 | Soluble |
| 126 | I | B | -0.6794 | Soluble |
| 127 | K | B | -1.4138 | Soluble |
| 128 | R | B | -1.1188 | Soluble |
| 129 | T | B | 0.1408 | Aggregation-prone |
| 130 | V | B | 1.2110 | Aggregation-prone |
| 131 | A | B | 0.6943 | Aggregation-prone |
| 132 | A | B | 0.3973 | Aggregation-prone |
| 133 | P | B | 0.0954 | Aggregation-prone |
| 134 | S | B | -0.1959 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0000 | Buried |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | 0.0000 | Buried |
| 140 | P | B | 0.0000 | Buried |
| 141 | S | B | 0.0000 | Buried |
| 142 | D | B | -3.2606 | Soluble |
| 143 | E | B | -3.3558 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.3836 | Soluble |
| 146 | K | B | -2.9679 | Soluble |
| 147 | S | B | -1.8514 | Soluble |
| 148 | G | B | -1.5362 | Soluble |
| 149 | T | B | -1.1695 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8003 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.4182 | Soluble |
| 162 | R | B | -2.9147 | Soluble |
| 163 | E | B | -3.0898 | Soluble |
| 164 | A | B | -2.2473 | Soluble |
| 165 | K | B | -2.2120 | Soluble |
| 166 | V | B | -1.2340 | Soluble |
| 167 | Q | B | -0.6213 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.5644 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.4806 | Soluble |
| 172 | N | B | -1.3372 | Soluble |
| 173 | A | B | -0.1513 | Soluble |
| 174 | L | B | 0.7172 | Aggregation-prone |
| 175 | Q | B | -0.1213 | Soluble |
| 176 | S | B | -0.4931 | Soluble |
| 177 | G | B | -0.8791 | Soluble |
| 178 | N | B | -0.7896 | Soluble |
| 179 | S | B | -1.1649 | Soluble |
| 180 | Q | B | -1.4726 | Soluble |
| 181 | E | B | -2.0210 | Soluble |
| 182 | S | B | -0.9106 | Soluble |
| 183 | V | B | -0.9013 | Soluble |
| 184 | T | B | -1.2091 | Soluble |
| 185 | E | B | -2.3301 | Soluble |
| 186 | Q | B | -1.9784 | Soluble |
| 187 | D | B | -2.0671 | Soluble |
| 188 | S | B | -1.8541 | Soluble |
| 189 | K | B | -2.4334 | Soluble |
| 190 | D | B | -1.9917 | Soluble |
| 191 | S | B | -1.9150 | Soluble |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7045 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.5025 | Soluble |
| 201 | L | B | -0.8092 | Soluble |
| 202 | S | B | -1.2556 | Soluble |
| 203 | K | B | -2.2756 | Soluble |
| 204 | A | B | -2.1453 | Soluble |
| 205 | D | B | -3.1055 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.5302 | Soluble |
| 208 | K | B | -3.7117 | Soluble |
| 209 | H | B | -3.0026 | Soluble |
| 210 | K | B | -3.1886 | Soluble |
| 211 | V | B | -1.4896 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.5600 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.0027 | Soluble |
| 218 | Q | B | -1.3497 | Soluble |
| 219 | G | B | -1.0567 | Soluble |
| 220 | T | B | -0.4358 | Soluble |
| 221 | T | B | -0.2179 | Soluble |
| 222 | S | B | -0.2355 | Soluble |
| 223 | V | B | 0.3712 | Aggregation-prone |
| 224 | T | B | -0.3848 | Soluble |
| 225 | K | B | -0.8924 | Soluble |
| 226 | S | B | -0.7107 | Soluble |
| 227 | F | B | 0.0000 | Buried |
| 228 | N | B | -1.6915 | Soluble |
| 229 | R | B | -2.3689 | Soluble |
| 230 | G | B | -2.1642 | Soluble |
| 231 | E | B | -2.1750 | Soluble |
| 232 | C | B | -0.6911 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.8306 | 2.6776 | CSV PDB |
| 4.5 | -0.8731 | 2.6781 | CSV PDB |
| 5.0 | -0.922 | 2.6797 | CSV PDB |
| 5.5 | -0.9667 | 2.6846 | CSV PDB |
| 6.0 | -0.9953 | 2.6976 | CSV PDB |
| 6.5 | -0.9981 | 2.7252 | CSV PDB |
| 7.0 | -0.9761 | 2.7686 | CSV PDB |
| 7.5 | -0.9393 | 2.8219 | CSV PDB |
| 8.0 | -0.8955 | 2.8795 | CSV PDB |
| 8.5 | -0.8463 | 2.9385 | CSV PDB |
| 9.0 | -0.7923 | 2.9977 | CSV PDB |