Calculation Parameters
| Chain Sequence(s) |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTWIHWVRQAPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGMMFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDIQMTQSPSSLSASVGDRVTITCRASQDIPRRISGYVAWYQQKPGKAPKLLIYWGSYLYSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -2.1391 | Soluble |
| 2 | V | A | -1.3365 | Soluble |
| 3 | Q | A | -1.3578 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | V | A | 0.3685 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.5273 | Soluble |
| 8 | G | A | -0.8634 | Soluble |
| 9 | G | A | -0.4602 | Soluble |
| 11 | G | A | -0.3752 | Soluble |
| 12 | L | A | -0.0032 | Soluble |
| 13 | V | A | -0.5619 | Soluble |
| 14 | Q | A | -1.5262 | Soluble |
| 15 | P | A | -1.3760 | Soluble |
| 16 | G | A | -1.3624 | Soluble |
| 17 | G | A | -1.0689 | Soluble |
| 18 | S | A | -1.1223 | Soluble |
| 19 | L | A | -0.7854 | Soluble |
| 20 | R | A | -1.7295 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.4466 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.3127 | Soluble |
| 25 | A | A | 0.0000 | Buried |
| 26 | S | A | -1.2903 | Soluble |
| 27 | G | A | -1.4862 | Soluble |
| 28 | F | A | -1.4905 | Soluble |
| 29 | N | A | -2.2603 | Soluble |
| 30 | I | A | 0.0000 | Buried |
| 35 | K | A | -2.7056 | Soluble |
| 36 | D | A | -2.2880 | Soluble |
| 37 | T | A | 0.0000 | Buried |
| 38 | W | A | 0.0000 | Buried |
| 39 | I | A | 0.0000 | Buried |
| 40 | H | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.7872 | Soluble |
| 45 | A | A | -1.2180 | Soluble |
| 46 | P | A | -1.1712 | Soluble |
| 47 | G | A | -1.4787 | Soluble |
| 48 | K | A | -2.3811 | Soluble |
| 49 | G | A | -1.6353 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.0417 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | A | A | 0.0000 | Buried |
| 55 | R | A | -0.3737 | Soluble |
| 56 | I | A | 0.0000 | Buried |
| 57 | Y | A | -0.5660 | Soluble |
| 58 | P | A | -1.1428 | Soluble |
| 59 | T | A | -1.4090 | Soluble |
| 62 | N | A | -1.4204 | Soluble |
| 63 | G | A | -0.6824 | Soluble |
| 64 | Y | A | -0.1432 | Soluble |
| 65 | T | A | -0.4577 | Soluble |
| 66 | R | A | -1.3436 | Soluble |
| 67 | Y | A | -1.5258 | Soluble |
| 68 | A | A | -1.6888 | Soluble |
| 69 | D | A | -2.5816 | Soluble |
| 70 | S | A | -1.7718 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.7883 | Soluble |
| 74 | G | A | -1.7993 | Soluble |
| 75 | R | A | -1.3778 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.9654 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.2585 | Soluble |
| 80 | A | A | -0.8520 | Soluble |
| 81 | D | A | -1.5007 | Soluble |
| 82 | T | A | -1.8592 | Soluble |
| 83 | S | A | -1.6496 | Soluble |
| 84 | K | A | -2.2440 | Soluble |
| 85 | N | A | -1.8308 | Soluble |
| 86 | T | A | 0.0000 | Buried |
| 87 | A | A | 0.0000 | Buried |
| 88 | Y | A | 0.0000 | Buried |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -1.0826 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.3579 | Soluble |
| 93 | S | A | -1.2444 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.2372 | Soluble |
| 96 | A | A | -1.6875 | Soluble |
| 97 | E | A | -2.2355 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.7027 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | 0.2274 | Aggregation-prone |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | S | A | 0.0000 | Buried |
| 106 | R | A | 0.0000 | Buried |
| 107 | W | A | 0.0000 | Buried |
| 108 | G | A | 0.0000 | Buried |
| 109 | G | A | -0.0583 | Soluble |
| 110 | M | A | 0.9261 | Aggregation-prone |
| 111 | M | A | 0.9253 | Aggregation-prone |
| 112 | F | A | 1.2299 | Aggregation-prone |
| 113 | Y | A | 1.0023 | Aggregation-prone |
| 114 | A | A | 0.0000 | Buried |
| 115 | M | A | 0.0000 | Buried |
| 116 | D | A | -0.0542 | Soluble |
| 117 | Y | A | -0.0216 | Soluble |
| 118 | W | A | -0.3508 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4906 | Soluble |
| 121 | G | A | -0.6597 | Soluble |
| 122 | T | A | -0.0898 | Soluble |
| 123 | L | A | 0.2099 | Aggregation-prone |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.3769 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.7296 | Soluble |
| 128 | S | A | -0.6774 | Soluble |
| 129 | A | A | -0.4359 | Soluble |
| 130 | S | A | -0.5584 | Soluble |
| 131 | T | A | -0.7058 | Soluble |
| 132 | K | A | -1.1586 | Soluble |
| 133 | G | A | -1.3475 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.6339 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.3412 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -0.8679 | Soluble |
| 141 | P | A | -0.9151 | Soluble |
| 142 | S | A | -1.4749 | Soluble |
| 143 | S | A | -1.6052 | Soluble |
| 144 | K | A | -2.2119 | Soluble |
| 145 | S | A | -1.2421 | Soluble |
| 146 | T | A | -0.8564 | Soluble |
| 147 | S | A | -0.6176 | Soluble |
| 148 | G | A | -0.8050 | Soluble |
| 149 | G | A | -0.8441 | Soluble |
| 150 | T | A | -0.6035 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | -0.3182 | Soluble |
| 159 | D | A | -0.4586 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.6176 | Soluble |
| 164 | P | A | -0.7292 | Soluble |
| 165 | V | A | -0.6761 | Soluble |
| 166 | T | A | -0.5405 | Soluble |
| 167 | V | A | -0.3251 | Soluble |
| 168 | S | A | -0.4044 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.7685 | Soluble |
| 171 | S | A | -0.6838 | Soluble |
| 172 | G | A | -0.5740 | Soluble |
| 173 | A | A | -0.2447 | Soluble |
| 174 | L | A | -0.0034 | Soluble |
| 175 | T | A | -0.1780 | Soluble |
| 176 | S | A | -0.1826 | Soluble |
| 177 | G | A | -0.2275 | Soluble |
| 178 | V | A | 0.1723 | Aggregation-prone |
| 179 | H | A | -0.3501 | Soluble |
| 180 | T | A | 0.0346 | Aggregation-prone |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.3532 | Soluble |
| 183 | A | A | 0.1926 | Aggregation-prone |
| 184 | V | A | 0.5324 | Aggregation-prone |
| 185 | L | A | 1.2261 | Aggregation-prone |
| 186 | Q | A | 0.2410 | Aggregation-prone |
| 187 | S | A | -0.0793 | Soluble |
| 188 | S | A | -0.2246 | Soluble |
| 189 | G | A | 0.0241 | Aggregation-prone |
| 190 | L | A | 0.1475 | Aggregation-prone |
| 191 | Y | A | 0.4366 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1246 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.5949 | Soluble |
| 201 | S | A | -0.5367 | Soluble |
| 202 | S | A | -0.5281 | Soluble |
| 203 | S | A | -0.5642 | Soluble |
| 204 | L | A | -0.7204 | Soluble |
| 205 | G | A | -1.2446 | Soluble |
| 206 | T | A | -0.8881 | Soluble |
| 207 | Q | A | -1.1936 | Soluble |
| 208 | T | A | -1.1074 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.2785 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.4457 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -1.9056 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.7678 | Soluble |
| 217 | P | A | -1.6356 | Soluble |
| 218 | S | A | -1.8591 | Soluble |
| 219 | N | A | -2.6148 | Soluble |
| 220 | T | A | -2.0643 | Soluble |
| 221 | K | A | -2.6609 | Soluble |
| 222 | V | A | -1.5351 | Soluble |
| 223 | D | A | -2.4702 | Soluble |
| 224 | K | A | -2.1049 | Soluble |
| 225 | K | A | -2.4972 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.8810 | Soluble |
| 228 | P | A | -1.8779 | Soluble |
| 229 | K | A | -2.4531 | Soluble |
| 230 | S | A | -1.0073 | Soluble |
| 231 | C | A | -0.1482 | Soluble |
| 1 | D | B | -2.1124 | Soluble |
| 2 | I | B | -1.6836 | Soluble |
| 3 | Q | B | -1.7987 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -1.2581 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.8648 | Soluble |
| 8 | P | B | -0.6226 | Soluble |
| 9 | S | B | -0.8882 | Soluble |
| 10 | S | B | -0.7491 | Soluble |
| 11 | L | B | -0.4196 | Soluble |
| 12 | S | B | -0.7326 | Soluble |
| 13 | A | B | -0.7789 | Soluble |
| 14 | S | B | -0.6631 | Soluble |
| 15 | V | B | 0.0598 | Aggregation-prone |
| 16 | G | B | -0.7491 | Soluble |
| 17 | D | B | -1.7481 | Soluble |
| 18 | R | B | -2.3134 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.6420 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.6509 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.2822 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -2.0784 | Soluble |
| 27 | Q | B | -2.7497 | Soluble |
| 28 | D | B | -2.7244 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 30 | P | B | -1.7661 | Soluble |
| 31 | R | B | -2.7433 | Soluble |
| 34 | R | B | -2.2160 | Soluble |
| 35 | I | B | -0.1004 | Soluble |
| 36 | S | B | -0.0712 | Soluble |
| 37 | G | B | 0.0000 | Buried |
| 38 | Y | B | 0.9989 | Aggregation-prone |
| 39 | V | B | 0.0000 | Buried |
| 40 | A | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.6547 | Soluble |
| 46 | P | B | -1.3806 | Soluble |
| 47 | G | B | -1.7359 | Soluble |
| 48 | K | B | -2.4862 | Soluble |
| 49 | A | B | -1.4982 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.2580 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | Y | B | 1.1729 | Aggregation-prone |
| 56 | W | B | 1.1552 | Aggregation-prone |
| 57 | G | B | 0.4832 | Aggregation-prone |
| 65 | S | B | 0.6506 | Aggregation-prone |
| 66 | Y | B | 1.6279 | Aggregation-prone |
| 67 | L | B | 1.2256 | Aggregation-prone |
| 68 | Y | B | 0.5258 | Aggregation-prone |
| 69 | S | B | -0.0602 | Soluble |
| 70 | G | B | -0.4659 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | P | B | -0.3478 | Soluble |
| 74 | S | B | -0.3942 | Soluble |
| 75 | R | B | -0.7178 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | S | B | -0.0172 | Soluble |
| 78 | G | B | 0.1070 | Aggregation-prone |
| 79 | S | B | -0.3656 | Soluble |
| 80 | G | B | -0.8575 | Soluble |
| 83 | S | B | -0.7778 | Soluble |
| 84 | G | B | -1.6221 | Soluble |
| 85 | T | B | -1.5948 | Soluble |
| 86 | D | B | -1.4714 | Soluble |
| 87 | F | B | -0.8838 | Soluble |
| 88 | T | B | -0.5570 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.6137 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.3468 | Soluble |
| 93 | S | B | -1.1031 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -1.0826 | Soluble |
| 96 | P | B | -1.6908 | Soluble |
| 97 | E | B | -2.2588 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | F | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.8394 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | H | B | 0.0000 | Buried |
| 108 | Y | B | 0.4545 | Aggregation-prone |
| 109 | T | B | -0.1509 | Soluble |
| 114 | T | B | -0.2384 | Soluble |
| 115 | P | B | -0.5588 | Soluble |
| 116 | P | B | 0.0000 | Buried |
| 117 | T | B | -0.5327 | Soluble |
| 118 | F | B | -0.4275 | Soluble |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.8077 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.5164 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.1734 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -0.9889 | Soluble |
| 128 | R | B | -0.6616 | Soluble |
| 129 | T | B | 0.0413 | Aggregation-prone |
| 130 | V | B | 0.5368 | Aggregation-prone |
| 131 | A | B | 0.0205 | Aggregation-prone |
| 132 | A | B | -0.1024 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.1110 | Soluble |
| 135 | V | B | 0.0187 | Aggregation-prone |
| 136 | F | B | 0.0800 | Aggregation-prone |
| 137 | I | B | 0.0000 | Buried |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.6796 | Soluble |
| 140 | P | B | -0.8477 | Soluble |
| 141 | S | B | -1.9702 | Soluble |
| 142 | D | B | -3.2614 | Soluble |
| 143 | E | B | -3.1752 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -2.3807 | Soluble |
| 146 | K | B | -2.9545 | Soluble |
| 147 | S | B | -1.8408 | Soluble |
| 148 | G | B | -1.3594 | Soluble |
| 149 | T | B | -1.3214 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -1.0358 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.6288 | Soluble |
| 162 | R | B | -2.8006 | Soluble |
| 163 | E | B | -3.1639 | Soluble |
| 164 | A | B | -2.3140 | Soluble |
| 165 | K | B | -2.3005 | Soluble |
| 166 | V | B | -1.1905 | Soluble |
| 167 | Q | B | -0.7618 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.7718 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.8747 | Soluble |
| 172 | N | B | -1.5380 | Soluble |
| 173 | A | B | -0.3534 | Soluble |
| 174 | L | B | 0.5110 | Aggregation-prone |
| 175 | Q | B | -0.1881 | Soluble |
| 176 | S | B | -0.4041 | Soluble |
| 177 | G | B | -0.7492 | Soluble |
| 178 | N | B | -0.8160 | Soluble |
| 179 | S | B | -1.1739 | Soluble |
| 180 | Q | B | -1.4407 | Soluble |
| 181 | E | B | -1.9929 | Soluble |
| 182 | S | B | -1.0830 | Soluble |
| 183 | V | B | -1.0859 | Soluble |
| 184 | T | B | -1.2367 | Soluble |
| 185 | E | B | -2.2916 | Soluble |
| 186 | Q | B | 0.0000 | Buried |
| 187 | D | B | -2.2487 | Soluble |
| 188 | S | B | -2.3618 | Soluble |
| 189 | K | B | -2.7624 | Soluble |
| 190 | D | B | -2.1452 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.7286 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.4946 | Soluble |
| 201 | L | B | -0.6632 | Soluble |
| 202 | S | B | -1.0887 | Soluble |
| 203 | K | B | -2.1539 | Soluble |
| 204 | A | B | -1.8280 | Soluble |
| 205 | D | B | -2.4454 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -2.9977 | Soluble |
| 208 | K | B | -3.3438 | Soluble |
| 209 | H | B | -2.6298 | Soluble |
| 210 | K | B | -2.5943 | Soluble |
| 211 | V | B | -1.0038 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | -0.8408 | Soluble |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -1.0730 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.2527 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6949 | Soluble |
| 220 | G | B | -0.3816 | Soluble |
| 221 | L | B | -0.2338 | Soluble |
| 222 | S | B | -0.4651 | Soluble |
| 223 | S | B | -0.4239 | Soluble |
| 224 | P | B | -0.5594 | Soluble |
| 225 | V | B | -0.0137 | Soluble |
| 226 | T | B | -0.4489 | Soluble |
| 227 | K | B | -0.6648 | Soluble |
| 228 | S | B | -0.6155 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.7511 | Soluble |
| 231 | R | B | -1.9649 | Soluble |
| 232 | G | B | -1.4710 | Soluble |
| 233 | E | B | -1.9624 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7674 | 2.2984 | CSV PDB |
| 4.5 | -0.8113 | 2.2924 | CSV PDB |
| 5.0 | -0.8616 | 2.2862 | CSV PDB |
| 5.5 | -0.9084 | 2.28 | CSV PDB |
| 6.0 | -0.9404 | 2.2738 | CSV PDB |
| 6.5 | -0.9485 | 2.2676 | CSV PDB |
| 7.0 | -0.9327 | 2.2617 | CSV PDB |
| 7.5 | -0.9011 | 2.2564 | CSV PDB |
| 8.0 | -0.8609 | 2.2522 | CSV PDB |
| 8.5 | -0.814 | 2.2497 | CSV PDB |
| 9.0 | -0.7602 | 2.2479 | CSV PDB |