Calculation Parameters
| Chain Sequence(s) |
QVQLQESGGGLVKPGGSLRLSCAASGFTFSHAWMHWVRQAPGKGLEWVGQIKAKSDDYATYYAESVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTCWEWDLDFWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSDIVMTQTPLSSPVTLGQPASISCRSSQSLLDSDGHTYLNWLQQRPGQPPRLLIYSVSNLESGVPDRFSGSGAGTDFTLKISRVEAEDVGVYYCMQATHAPPYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
input.pdb
|
| Selected Chain(s) | B (Heavy), A (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | Q | B | -1.4829 | Soluble |
| 2 | V | B | -0.9174 | Soluble |
| 3 | Q | B | -1.6430 | Soluble |
| 4 | L | B | 0.0000 | Buried |
| 5 | Q | B | -1.4535 | Soluble |
| 6 | E | B | 0.0000 | Buried |
| 7 | S | B | -0.8471 | Soluble |
| 8 | G | B | -0.9231 | Soluble |
| 9 | G | B | -0.5735 | Soluble |
| 11 | G | B | -0.5910 | Soluble |
| 12 | L | B | -0.3284 | Soluble |
| 13 | V | B | 0.0000 | Buried |
| 14 | K | B | -2.1134 | Soluble |
| 15 | P | B | -1.9230 | Soluble |
| 16 | G | B | -1.5419 | Soluble |
| 17 | G | B | -1.2965 | Soluble |
| 18 | S | B | -1.3557 | Soluble |
| 19 | L | B | -1.1778 | Soluble |
| 20 | R | B | -2.1129 | Soluble |
| 21 | L | B | 0.0000 | Buried |
| 22 | S | B | -0.7819 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | A | B | -0.9821 | Soluble |
| 25 | A | B | 0.0000 | Buried |
| 26 | S | B | -1.2431 | Soluble |
| 27 | G | B | -1.0099 | Soluble |
| 28 | F | B | -0.5315 | Soluble |
| 29 | T | B | -0.4407 | Soluble |
| 30 | F | B | 0.0000 | Buried |
| 35 | S | B | -1.2307 | Soluble |
| 36 | H | B | -1.5300 | Soluble |
| 37 | A | B | 0.0000 | Buried |
| 38 | W | B | 0.0292 | Aggregation-prone |
| 39 | M | B | 0.0000 | Buried |
| 40 | H | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | V | B | 0.0000 | Buried |
| 43 | R | B | 0.0000 | Buried |
| 44 | Q | B | -0.7883 | Soluble |
| 45 | A | B | -1.2171 | Soluble |
| 46 | P | B | -0.9864 | Soluble |
| 47 | G | B | -1.4667 | Soluble |
| 48 | K | B | -2.4001 | Soluble |
| 49 | G | B | -1.6408 | Soluble |
| 50 | L | B | 0.0000 | Buried |
| 51 | E | B | -1.1109 | Soluble |
| 52 | W | B | 0.0000 | Buried |
| 53 | V | B | 0.0000 | Buried |
| 54 | G | B | 0.0000 | Buried |
| 55 | Q | B | 0.0000 | Buried |
| 56 | I | B | 0.0000 | Buried |
| 57 | K | B | -1.2259 | Soluble |
| 58 | A | B | 0.0000 | Buried |
| 59 | K | B | -3.1569 | Soluble |
| 60 | S | B | -2.4369 | Soluble |
| 61 | D | B | -2.9766 | Soluble |
| 62 | D | B | -3.0909 | Soluble |
| 63 | Y | B | -1.5140 | Soluble |
| 64 | A | B | -0.9411 | Soluble |
| 65 | T | B | 0.0332 | Aggregation-prone |
| 66 | Y | B | 0.3645 | Aggregation-prone |
| 67 | Y | B | -0.5974 | Soluble |
| 68 | A | B | -1.3309 | Soluble |
| 69 | E | B | -2.4997 | Soluble |
| 70 | S | B | -1.8721 | Soluble |
| 71 | V | B | 0.0000 | Buried |
| 72 | K | B | -2.5588 | Soluble |
| 74 | G | B | -1.8089 | Soluble |
| 75 | R | B | -1.5753 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | T | B | -0.8411 | Soluble |
| 78 | I | B | 0.0000 | Buried |
| 79 | S | B | -0.5157 | Soluble |
| 80 | R | B | 0.0000 | Buried |
| 81 | D | B | -1.5102 | Soluble |
| 82 | D | B | -1.8705 | Soluble |
| 83 | S | B | -1.5720 | Soluble |
| 84 | K | B | -2.3784 | Soluble |
| 85 | N | B | -1.8048 | Soluble |
| 86 | T | B | -1.2702 | Soluble |
| 87 | L | B | 0.0000 | Buried |
| 88 | Y | B | 0.0000 | Buried |
| 89 | L | B | 0.0000 | Buried |
| 90 | Q | B | -1.4227 | Soluble |
| 91 | M | B | 0.0000 | Buried |
| 92 | N | B | -1.3915 | Soluble |
| 93 | S | B | -1.2922 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | K | B | -2.3935 | Soluble |
| 96 | T | B | -1.9015 | Soluble |
| 97 | E | B | -2.2831 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | T | B | -0.7666 | Soluble |
| 100 | A | B | 0.0000 | Buried |
| 101 | V | B | 0.1955 | Aggregation-prone |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | T | B | 0.0000 | Buried |
| 106 | C | B | 0.0000 | Buried |
| 107 | W | B | 0.0000 | Buried |
| 108 | E | B | -0.2811 | Soluble |
| 109 | W | B | 0.2681 | Aggregation-prone |
| 114 | D | B | -1.1676 | Soluble |
| 115 | L | B | -0.3440 | Soluble |
| 116 | D | B | -0.4833 | Soluble |
| 117 | F | B | -0.0409 | Soluble |
| 118 | W | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | Q | B | -1.7915 | Soluble |
| 121 | G | B | 0.0000 | Buried |
| 122 | T | B | 0.0000 | Buried |
| 123 | M | B | -0.1100 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | T | B | 0.0000 | Buried |
| 126 | V | B | 0.0000 | Buried |
| 127 | S | B | -1.1192 | Soluble |
| 128 | S | B | -0.8139 | Soluble |
| 129 | A | B | -0.5489 | Soluble |
| 130 | S | B | -0.6517 | Soluble |
| 131 | T | B | -0.7344 | Soluble |
| 132 | K | B | -1.3850 | Soluble |
| 133 | G | B | -1.5160 | Soluble |
| 134 | P | B | -0.7692 | Soluble |
| 135 | S | B | -0.3611 | Soluble |
| 136 | V | B | 0.0000 | Buried |
| 137 | F | B | 0.0000 | Buried |
| 138 | P | B | -1.3128 | Soluble |
| 139 | L | B | 0.0000 | Buried |
| 140 | A | B | 0.0000 | Buried |
| 141 | P | B | -0.9982 | Soluble |
| 142 | S | B | -1.5129 | Soluble |
| 143 | S | B | -1.8487 | Soluble |
| 144 | K | B | -2.2378 | Soluble |
| 145 | S | B | -1.2923 | Soluble |
| 146 | T | B | -1.0009 | Soluble |
| 147 | S | B | -0.8009 | Soluble |
| 148 | G | B | -0.8641 | Soluble |
| 149 | G | B | -0.8460 | Soluble |
| 150 | T | B | -0.6173 | Soluble |
| 151 | A | B | -0.3613 | Soluble |
| 152 | A | B | 0.0000 | Buried |
| 153 | L | B | 0.0000 | Buried |
| 154 | G | B | 0.0000 | Buried |
| 155 | C | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | V | B | 0.0000 | Buried |
| 158 | K | B | 0.0000 | Buried |
| 159 | D | B | -0.6785 | Soluble |
| 160 | Y | B | 0.0000 | Buried |
| 161 | F | B | -0.4132 | Soluble |
| 162 | P | B | 0.0000 | Buried |
| 163 | E | B | -0.8938 | Soluble |
| 164 | P | B | -0.7959 | Soluble |
| 165 | V | B | -0.6916 | Soluble |
| 166 | T | B | -0.7746 | Soluble |
| 167 | V | B | -0.2233 | Soluble |
| 168 | S | B | -0.3472 | Soluble |
| 169 | W | B | 0.0000 | Buried |
| 170 | N | B | -0.6691 | Soluble |
| 171 | S | B | -0.5526 | Soluble |
| 172 | G | B | -0.5351 | Soluble |
| 173 | A | B | -0.2545 | Soluble |
| 174 | L | B | -0.0212 | Soluble |
| 175 | T | B | -0.1691 | Soluble |
| 176 | S | B | -0.1834 | Soluble |
| 177 | G | B | -0.1866 | Soluble |
| 178 | V | B | 0.1714 | Aggregation-prone |
| 179 | H | B | -0.0823 | Soluble |
| 180 | T | B | 0.0079 | Aggregation-prone |
| 181 | F | B | 0.0000 | Buried |
| 182 | P | B | -0.4610 | Soluble |
| 183 | A | B | 0.0425 | Aggregation-prone |
| 184 | V | B | 0.2548 | Aggregation-prone |
| 185 | L | B | 1.1464 | Aggregation-prone |
| 186 | Q | B | 0.1098 | Aggregation-prone |
| 187 | S | B | -0.1390 | Soluble |
| 188 | S | B | -0.3359 | Soluble |
| 189 | G | B | -0.1056 | Soluble |
| 190 | L | B | -0.0772 | Soluble |
| 191 | Y | B | 0.3135 | Aggregation-prone |
| 192 | S | B | 0.0121 | Aggregation-prone |
| 193 | L | B | 0.0000 | Buried |
| 194 | S | B | -0.0301 | Soluble |
| 195 | S | B | 0.0000 | Buried |
| 196 | V | B | 0.0000 | Buried |
| 197 | V | B | 0.0000 | Buried |
| 198 | T | B | -0.1078 | Soluble |
| 199 | V | B | 0.0000 | Buried |
| 200 | P | B | -0.6176 | Soluble |
| 201 | S | B | -0.7122 | Soluble |
| 202 | S | B | -0.6598 | Soluble |
| 203 | S | B | -0.6625 | Soluble |
| 204 | L | B | -0.8219 | Soluble |
| 205 | G | B | -0.9980 | Soluble |
| 206 | T | B | -0.7807 | Soluble |
| 207 | Q | B | -1.3279 | Soluble |
| 208 | T | B | -1.2080 | Soluble |
| 209 | Y | B | 0.0000 | Buried |
| 210 | I | B | -1.0446 | Soluble |
| 211 | C | B | 0.0000 | Buried |
| 212 | N | B | -1.2144 | Soluble |
| 213 | V | B | 0.0000 | Buried |
| 214 | N | B | -2.2384 | Soluble |
| 215 | H | B | 0.0000 | Buried |
| 216 | K | B | -2.8406 | Soluble |
| 217 | P | B | -1.6101 | Soluble |
| 218 | S | B | -1.8470 | Soluble |
| 219 | N | B | -2.7201 | Soluble |
| 220 | T | B | -2.2792 | Soluble |
| 221 | K | B | -2.6931 | Soluble |
| 222 | V | B | -1.5109 | Soluble |
| 223 | D | B | -1.6074 | Soluble |
| 224 | K | B | -1.6167 | Soluble |
| 225 | K | B | -2.3555 | Soluble |
| 226 | V | B | 0.0000 | Buried |
| 227 | E | B | -2.9238 | Soluble |
| 228 | P | B | -1.9905 | Soluble |
| 229 | K | B | -2.6446 | Soluble |
| 230 | S | B | -1.4587 | Soluble |
| 1 | D | A | -1.5354 | Soluble |
| 2 | I | A | -0.1996 | Soluble |
| 3 | V | A | 0.8326 | Aggregation-prone |
| 4 | M | A | 0.0000 | Buried |
| 5 | T | A | -0.6763 | Soluble |
| 6 | Q | A | 0.0000 | Buried |
| 7 | T | A | -0.5682 | Soluble |
| 8 | P | A | -0.5488 | Soluble |
| 9 | L | A | -0.2056 | Soluble |
| 10 | S | A | -0.1323 | Soluble |
| 11 | S | A | -0.2887 | Soluble |
| 12 | P | A | -0.5510 | Soluble |
| 13 | V | A | -0.8082 | Soluble |
| 14 | T | A | -0.9380 | Soluble |
| 15 | L | A | -0.9216 | Soluble |
| 16 | G | A | -1.8062 | Soluble |
| 17 | Q | A | -1.8405 | Soluble |
| 18 | P | A | -1.6107 | Soluble |
| 19 | A | A | -1.0629 | Soluble |
| 20 | S | A | -0.6284 | Soluble |
| 21 | I | A | 0.0000 | Buried |
| 22 | S | A | -0.9610 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | R | A | -2.1592 | Soluble |
| 25 | S | A | -1.0239 | Soluble |
| 26 | S | A | -0.8977 | Soluble |
| 27 | Q | A | -1.4380 | Soluble |
| 28 | S | A | -0.7644 | Soluble |
| 29 | L | A | 0.0000 | Buried |
| 30 | L | A | 0.2769 | Aggregation-prone |
| 31 | D | A | -1.0803 | Soluble |
| 32 | S | A | -1.4216 | Soluble |
| 34 | D | A | -2.3883 | Soluble |
| 35 | G | A | -1.6777 | Soluble |
| 36 | H | A | -1.4487 | Soluble |
| 37 | T | A | -0.2367 | Soluble |
| 38 | Y | A | 0.2977 | Aggregation-prone |
| 39 | L | A | 0.0000 | Buried |
| 40 | N | A | 0.1789 | Aggregation-prone |
| 41 | W | A | 0.0000 | Buried |
| 42 | L | A | 0.0000 | Buried |
| 43 | Q | A | 0.0000 | Buried |
| 44 | Q | A | -0.9931 | Soluble |
| 45 | R | A | -1.4259 | Soluble |
| 46 | P | A | -1.3447 | Soluble |
| 47 | G | A | -1.5355 | Soluble |
| 48 | Q | A | -1.9170 | Soluble |
| 49 | P | A | -1.2539 | Soluble |
| 50 | P | A | 0.0000 | Buried |
| 51 | R | A | -0.9033 | Soluble |
| 52 | L | A | -0.1850 | Soluble |
| 53 | L | A | 0.0000 | Buried |
| 54 | I | A | 0.0000 | Buried |
| 55 | Y | A | 0.3708 | Aggregation-prone |
| 56 | S | A | -0.0326 | Soluble |
| 57 | V | A | -0.1163 | Soluble |
| 65 | S | A | -0.5320 | Soluble |
| 66 | N | A | -0.8172 | Soluble |
| 67 | L | A | -0.6624 | Soluble |
| 68 | E | A | -1.0693 | Soluble |
| 69 | S | A | -0.9336 | Soluble |
| 70 | G | A | -0.8579 | Soluble |
| 71 | V | A | -0.6969 | Soluble |
| 72 | P | A | -1.0770 | Soluble |
| 74 | D | A | -1.9278 | Soluble |
| 75 | R | A | 0.0000 | Buried |
| 76 | F | A | 0.0000 | Buried |
| 77 | S | A | -1.1501 | Soluble |
| 78 | G | A | -0.6372 | Soluble |
| 79 | S | A | -0.7614 | Soluble |
| 80 | G | A | -0.7718 | Soluble |
| 83 | A | A | -0.1239 | Soluble |
| 84 | G | A | -0.4351 | Soluble |
| 85 | T | A | -1.2113 | Soluble |
| 86 | D | A | -1.7604 | Soluble |
| 87 | F | A | 0.0000 | Buried |
| 88 | T | A | -0.9241 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | K | A | -1.6032 | Soluble |
| 91 | I | A | 0.0000 | Buried |
| 92 | S | A | -2.2032 | Soluble |
| 93 | R | A | -2.8620 | Soluble |
| 94 | V | A | 0.0000 | Buried |
| 95 | E | A | -2.6957 | Soluble |
| 96 | A | A | -2.1129 | Soluble |
| 97 | E | A | -1.9197 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | V | A | 0.0000 | Buried |
| 100 | G | A | 0.0000 | Buried |
| 101 | V | A | -0.7624 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | M | A | 0.0000 | Buried |
| 106 | Q | A | 0.0000 | Buried |
| 107 | A | A | -0.0997 | Soluble |
| 108 | T | A | -0.2067 | Soluble |
| 109 | H | A | -0.7915 | Soluble |
| 113 | A | A | -0.3960 | Soluble |
| 114 | P | A | -0.2862 | Soluble |
| 115 | P | A | -0.6750 | Soluble |
| 116 | Y | A | -0.1313 | Soluble |
| 117 | T | A | -0.1061 | Soluble |
| 118 | F | A | 0.0000 | Buried |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.6258 | Soluble |
| 121 | G | A | -1.2328 | Soluble |
| 122 | T | A | 0.0000 | Buried |
| 123 | K | A | -1.6587 | Soluble |
| 124 | L | A | 0.0000 | Buried |
| 125 | E | A | -1.1080 | Soluble |
| 126 | I | A | 0.0000 | Buried |
| 127 | K | A | -0.7971 | Soluble |
| 128 | R | A | -0.4593 | Soluble |
| 129 | T | A | 0.1497 | Aggregation-prone |
| 130 | V | A | 0.3829 | Aggregation-prone |
| 131 | A | A | 0.1728 | Aggregation-prone |
| 132 | A | A | -0.0842 | Soluble |
| 133 | P | A | 0.0000 | Buried |
| 134 | S | A | -0.1453 | Soluble |
| 135 | V | A | 0.0000 | Buried |
| 136 | F | A | 0.0844 | Aggregation-prone |
| 137 | I | A | -0.0575 | Soluble |
| 138 | F | A | 0.0000 | Buried |
| 139 | P | A | -0.6091 | Soluble |
| 140 | P | A | -0.7324 | Soluble |
| 141 | S | A | 0.0000 | Buried |
| 142 | D | A | -2.9188 | Soluble |
| 143 | E | A | -2.6171 | Soluble |
| 144 | Q | A | 0.0000 | Buried |
| 145 | L | A | -2.0256 | Soluble |
| 146 | K | A | -2.6196 | Soluble |
| 147 | S | A | -1.6434 | Soluble |
| 148 | G | A | -1.1785 | Soluble |
| 149 | T | A | -0.8170 | Soluble |
| 150 | A | A | 0.0000 | Buried |
| 151 | S | A | 0.0000 | Buried |
| 152 | V | A | 0.0000 | Buried |
| 153 | V | A | 0.0000 | Buried |
| 154 | C | A | 0.0000 | Buried |
| 155 | L | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | N | A | 0.0000 | Buried |
| 158 | N | A | -0.8033 | Soluble |
| 159 | F | A | 0.0000 | Buried |
| 160 | Y | A | -1.0324 | Soluble |
| 161 | P | A | -1.6542 | Soluble |
| 162 | R | A | -3.1104 | Soluble |
| 163 | E | A | -3.2640 | Soluble |
| 164 | A | A | -2.3618 | Soluble |
| 165 | K | A | -2.5240 | Soluble |
| 166 | V | A | -1.2066 | Soluble |
| 167 | Q | A | -0.8286 | Soluble |
| 168 | W | A | 0.0000 | Buried |
| 169 | K | A | -0.6688 | Soluble |
| 170 | V | A | 0.0000 | Buried |
| 171 | D | A | -1.8353 | Soluble |
| 172 | N | A | -1.5110 | Soluble |
| 173 | A | A | -0.2783 | Soluble |
| 174 | L | A | 0.6844 | Aggregation-prone |
| 175 | Q | A | -0.1939 | Soluble |
| 176 | S | A | -0.6002 | Soluble |
| 177 | G | A | -0.9944 | Soluble |
| 178 | N | A | -0.9660 | Soluble |
| 179 | S | A | -1.4508 | Soluble |
| 180 | Q | A | -1.9005 | Soluble |
| 181 | E | A | -2.2165 | Soluble |
| 182 | S | A | -0.9596 | Soluble |
| 183 | V | A | -0.8218 | Soluble |
| 184 | T | A | -1.1902 | Soluble |
| 185 | E | A | -2.2994 | Soluble |
| 186 | Q | A | 0.0000 | Buried |
| 187 | D | A | -2.0730 | Soluble |
| 188 | S | A | -2.1959 | Soluble |
| 189 | K | A | -2.6256 | Soluble |
| 190 | D | A | -1.9755 | Soluble |
| 191 | S | A | 0.0000 | Buried |
| 192 | T | A | 0.0000 | Buried |
| 193 | Y | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | L | A | 0.0000 | Buried |
| 196 | S | A | 0.0000 | Buried |
| 197 | S | A | 0.0000 | Buried |
| 198 | T | A | -0.8524 | Soluble |
| 199 | L | A | 0.0000 | Buried |
| 200 | T | A | -0.5146 | Soluble |
| 201 | L | A | -0.6049 | Soluble |
| 202 | S | A | -0.9538 | Soluble |
| 203 | K | A | -1.8456 | Soluble |
| 204 | A | A | -1.6463 | Soluble |
| 205 | D | A | -2.2942 | Soluble |
| 206 | Y | A | 0.0000 | Buried |
| 207 | E | A | -2.7176 | Soluble |
| 208 | K | A | -3.2284 | Soluble |
| 209 | H | A | -2.6536 | Soluble |
| 210 | K | A | -2.7338 | Soluble |
| 211 | V | A | -1.1920 | Soluble |
| 212 | Y | A | 0.0000 | Buried |
| 213 | A | A | 0.0000 | Buried |
| 214 | C | A | 0.0000 | Buried |
| 215 | E | A | -0.9053 | Soluble |
| 216 | V | A | 0.0000 | Buried |
| 217 | T | A | -1.2493 | Soluble |
| 218 | H | A | 0.0000 | Buried |
| 219 | Q | A | -1.7838 | Soluble |
| 220 | G | A | -0.4776 | Soluble |
| 221 | L | A | -0.2716 | Soluble |
| 222 | S | A | -0.4727 | Soluble |
| 223 | S | A | -0.4536 | Soluble |
| 224 | P | A | -0.5259 | Soluble |
| 225 | V | A | 0.0988 | Aggregation-prone |
| 226 | T | A | -0.3013 | Soluble |
| 227 | K | A | -0.5562 | Soluble |
| 228 | S | A | -0.5945 | Soluble |
| 229 | F | A | 0.0000 | Buried |
| 230 | N | A | -1.8438 | Soluble |
| 231 | R | A | -2.0056 | Soluble |
| 232 | G | A | -1.7524 | Soluble |
| 233 | E | A | -2.2578 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.7737 | 3.7242 | CSV PDB |
| 4.5 | -0.8235 | 3.531 | CSV PDB |
| 5.0 | -0.8799 | 3.2884 | CSV PDB |
| 5.5 | -0.9304 | 3.0241 | CSV PDB |
| 6.0 | -0.9624 | 2.7546 | CSV PDB |
| 6.5 | -0.9676 | 2.4896 | CSV PDB |
| 7.0 | -0.9488 | 2.2348 | CSV PDB |
| 7.5 | -0.9161 | 1.9904 | CSV PDB |
| 8.0 | -0.8763 | 1.7565 | CSV PDB |
| 8.5 | -0.8307 | 1.5415 | CSV PDB |
| 9.0 | -0.7781 | 1.6154 | CSV PDB |