Calculation Parameters
| Chain Sequence(s) |
EVQLLESGGGLVQPGGSLRLSCAASGFTFSIYSMNWVRQAPGKGLEWVSSIGSSGGTTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAGSQWLYGMDVWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHDIQMTQSPSSLSASVGDRVTITCRSSQRIMTYLNWYQQKPGKAPKLLIFVASHSQSGVPSRFRGSGSETDFTLTISGLQPEDSATYYCQQSFWTPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
input.pdb
|
| Selected Chain(s) | A (Heavy), B (Light) |
| Distance of Aggregation | 10 Å |
| FoldX Energy Minimization | Yes |
| pH Calculations | Yes |
| Downloads | Download all data (.tar.gz) |
Aggrescan4D Profile
Per-Residue A4D Scores
Download CSVResidues with A4D score > 0.0 are highlighted as aggregation-prone.
| Index | Residue | Chain | A4D Score | Classification |
|---|---|---|---|---|
| 1 | E | A | -1.3947 | Soluble |
| 2 | V | A | 0.1500 | Aggregation-prone |
| 3 | Q | A | -0.5215 | Soluble |
| 4 | L | A | 0.0000 | Buried |
| 5 | L | A | 0.3068 | Aggregation-prone |
| 6 | E | A | 0.0000 | Buried |
| 7 | S | A | -0.4816 | Soluble |
| 8 | G | A | -0.7693 | Soluble |
| 9 | G | A | -0.7319 | Soluble |
| 11 | G | A | -0.5789 | Soluble |
| 12 | L | A | -0.3455 | Soluble |
| 13 | V | A | 0.0000 | Buried |
| 14 | Q | A | -1.7398 | Soluble |
| 15 | P | A | -1.9197 | Soluble |
| 16 | G | A | -1.6116 | Soluble |
| 17 | G | A | -1.1335 | Soluble |
| 18 | S | A | -0.9070 | Soluble |
| 19 | L | A | -0.7255 | Soluble |
| 20 | R | A | -1.3483 | Soluble |
| 21 | L | A | 0.0000 | Buried |
| 22 | S | A | -0.3478 | Soluble |
| 23 | C | A | 0.0000 | Buried |
| 24 | A | A | -0.3923 | Soluble |
| 25 | A | A | -0.3065 | Soluble |
| 26 | S | A | -0.3987 | Soluble |
| 27 | G | A | -0.5158 | Soluble |
| 28 | F | A | 0.2140 | Aggregation-prone |
| 29 | T | A | 0.4295 | Aggregation-prone |
| 30 | F | A | 0.0000 | Buried |
| 35 | S | A | 0.1271 | Aggregation-prone |
| 36 | I | A | 1.3188 | Aggregation-prone |
| 37 | Y | A | 0.7717 | Aggregation-prone |
| 38 | S | A | 0.3718 | Aggregation-prone |
| 39 | M | A | 0.0000 | Buried |
| 40 | N | A | 0.0000 | Buried |
| 41 | W | A | 0.0000 | Buried |
| 42 | V | A | 0.0000 | Buried |
| 43 | R | A | 0.0000 | Buried |
| 44 | Q | A | -0.9455 | Soluble |
| 45 | A | A | -1.3607 | Soluble |
| 46 | P | A | -1.2936 | Soluble |
| 47 | G | A | -1.4733 | Soluble |
| 48 | K | A | -2.3046 | Soluble |
| 49 | G | A | -1.5170 | Soluble |
| 50 | L | A | 0.0000 | Buried |
| 51 | E | A | -1.1830 | Soluble |
| 52 | W | A | 0.0000 | Buried |
| 53 | V | A | 0.0000 | Buried |
| 54 | S | A | 0.0000 | Buried |
| 55 | S | A | 0.0000 | Buried |
| 56 | I | A | 0.0000 | Buried |
| 57 | G | A | 0.0300 | Aggregation-prone |
| 58 | S | A | 0.1201 | Aggregation-prone |
| 59 | S | A | -0.2926 | Soluble |
| 62 | G | A | -0.7590 | Soluble |
| 63 | G | A | -0.5883 | Soluble |
| 64 | T | A | -0.2610 | Soluble |
| 65 | T | A | 0.1349 | Aggregation-prone |
| 66 | Y | A | 0.2587 | Aggregation-prone |
| 67 | Y | A | -0.5607 | Soluble |
| 68 | A | A | -1.4859 | Soluble |
| 69 | D | A | -2.6228 | Soluble |
| 70 | S | A | -1.8921 | Soluble |
| 71 | V | A | 0.0000 | Buried |
| 72 | K | A | -2.5596 | Soluble |
| 74 | G | A | -1.7844 | Soluble |
| 75 | R | A | -1.3336 | Soluble |
| 76 | F | A | 0.0000 | Buried |
| 77 | T | A | -0.6566 | Soluble |
| 78 | I | A | 0.0000 | Buried |
| 79 | S | A | -0.5044 | Soluble |
| 80 | R | A | -1.1674 | Soluble |
| 81 | D | A | -1.7731 | Soluble |
| 82 | N | A | -1.8014 | Soluble |
| 83 | S | A | -1.7389 | Soluble |
| 84 | K | A | -2.4879 | Soluble |
| 85 | N | A | -1.9590 | Soluble |
| 86 | T | A | -1.1801 | Soluble |
| 87 | L | A | 0.0000 | Buried |
| 88 | Y | A | -0.4283 | Soluble |
| 89 | L | A | 0.0000 | Buried |
| 90 | Q | A | -0.8407 | Soluble |
| 91 | M | A | 0.0000 | Buried |
| 92 | N | A | -1.3343 | Soluble |
| 93 | S | A | -1.3961 | Soluble |
| 94 | L | A | 0.0000 | Buried |
| 95 | R | A | -2.8695 | Soluble |
| 96 | A | A | -2.0421 | Soluble |
| 97 | E | A | -2.4445 | Soluble |
| 98 | D | A | 0.0000 | Buried |
| 99 | T | A | -0.9668 | Soluble |
| 100 | A | A | 0.0000 | Buried |
| 101 | V | A | -0.0571 | Soluble |
| 102 | Y | A | 0.0000 | Buried |
| 103 | Y | A | 0.0000 | Buried |
| 104 | C | A | 0.0000 | Buried |
| 105 | A | A | 0.0000 | Buried |
| 106 | G | A | 0.0000 | Buried |
| 107 | S | A | 0.0000 | Buried |
| 108 | Q | A | 0.6613 | Aggregation-prone |
| 109 | W | A | 1.5822 | Aggregation-prone |
| 110 | L | A | 1.6891 | Aggregation-prone |
| 113 | Y | A | 1.2738 | Aggregation-prone |
| 114 | G | A | 0.0000 | Buried |
| 115 | M | A | 0.0000 | Buried |
| 116 | D | A | -0.6885 | Soluble |
| 117 | V | A | 0.0000 | Buried |
| 118 | W | A | -0.2851 | Soluble |
| 119 | G | A | 0.0000 | Buried |
| 120 | Q | A | -1.4600 | Soluble |
| 121 | G | A | -0.7680 | Soluble |
| 122 | T | A | -0.2677 | Soluble |
| 123 | T | A | -0.1621 | Soluble |
| 124 | V | A | 0.0000 | Buried |
| 125 | T | A | -0.6540 | Soluble |
| 126 | V | A | 0.0000 | Buried |
| 127 | S | A | -0.8813 | Soluble |
| 128 | S | A | -0.7708 | Soluble |
| 129 | A | A | -0.5397 | Soluble |
| 130 | S | A | -0.6648 | Soluble |
| 131 | T | A | -0.9426 | Soluble |
| 132 | K | A | -1.5808 | Soluble |
| 133 | G | A | -1.6253 | Soluble |
| 134 | P | A | 0.0000 | Buried |
| 135 | S | A | -0.4648 | Soluble |
| 136 | V | A | 0.0000 | Buried |
| 137 | F | A | 0.0000 | Buried |
| 138 | P | A | -1.1805 | Soluble |
| 139 | L | A | 0.0000 | Buried |
| 140 | A | A | -1.0967 | Soluble |
| 141 | P | A | 0.0000 | Buried |
| 142 | S | A | -1.1263 | Soluble |
| 143 | S | A | -1.5913 | Soluble |
| 144 | K | A | -1.9504 | Soluble |
| 145 | S | A | -1.1445 | Soluble |
| 146 | T | A | -1.0756 | Soluble |
| 147 | S | A | -0.7999 | Soluble |
| 148 | G | A | -0.9702 | Soluble |
| 149 | G | A | -0.8964 | Soluble |
| 150 | T | A | -0.6149 | Soluble |
| 151 | A | A | 0.0000 | Buried |
| 152 | A | A | 0.0000 | Buried |
| 153 | L | A | 0.0000 | Buried |
| 154 | G | A | 0.0000 | Buried |
| 155 | C | A | 0.0000 | Buried |
| 156 | L | A | 0.0000 | Buried |
| 157 | V | A | 0.0000 | Buried |
| 158 | K | A | 0.0000 | Buried |
| 159 | D | A | -0.6506 | Soluble |
| 160 | Y | A | 0.0000 | Buried |
| 161 | F | A | 0.0000 | Buried |
| 162 | P | A | 0.0000 | Buried |
| 163 | E | A | -0.5832 | Soluble |
| 164 | P | A | -0.6853 | Soluble |
| 165 | V | A | -0.6694 | Soluble |
| 166 | T | A | -0.6303 | Soluble |
| 167 | V | A | -0.3894 | Soluble |
| 168 | S | A | -0.4722 | Soluble |
| 169 | W | A | 0.0000 | Buried |
| 170 | N | A | -0.9396 | Soluble |
| 171 | S | A | -0.7516 | Soluble |
| 172 | G | A | -0.6256 | Soluble |
| 173 | A | A | -0.2733 | Soluble |
| 174 | L | A | -0.0169 | Soluble |
| 175 | T | A | -0.1905 | Soluble |
| 176 | S | A | -0.2171 | Soluble |
| 177 | G | A | -0.2246 | Soluble |
| 178 | V | A | 0.1387 | Aggregation-prone |
| 179 | H | A | -0.3462 | Soluble |
| 180 | T | A | -0.1776 | Soluble |
| 181 | F | A | 0.0000 | Buried |
| 182 | P | A | -0.2710 | Soluble |
| 183 | A | A | 0.3500 | Aggregation-prone |
| 184 | V | A | 0.8200 | Aggregation-prone |
| 185 | L | A | 1.4473 | Aggregation-prone |
| 186 | Q | A | 0.4321 | Aggregation-prone |
| 187 | S | A | -0.0420 | Soluble |
| 188 | S | A | -0.2576 | Soluble |
| 189 | G | A | -0.0737 | Soluble |
| 190 | L | A | 0.0139 | Aggregation-prone |
| 191 | Y | A | 0.5960 | Aggregation-prone |
| 192 | S | A | 0.0000 | Buried |
| 193 | L | A | 0.0000 | Buried |
| 194 | S | A | 0.0000 | Buried |
| 195 | S | A | 0.0000 | Buried |
| 196 | V | A | 0.0000 | Buried |
| 197 | V | A | 0.0000 | Buried |
| 198 | T | A | -0.1803 | Soluble |
| 199 | V | A | 0.0000 | Buried |
| 200 | P | A | -0.6272 | Soluble |
| 201 | S | A | -0.8556 | Soluble |
| 202 | S | A | -0.5829 | Soluble |
| 203 | S | A | -0.6315 | Soluble |
| 204 | L | A | -0.8133 | Soluble |
| 205 | G | A | -1.0341 | Soluble |
| 206 | T | A | -0.7292 | Soluble |
| 207 | Q | A | -1.2443 | Soluble |
| 208 | T | A | -1.2178 | Soluble |
| 209 | Y | A | 0.0000 | Buried |
| 210 | I | A | -1.5034 | Soluble |
| 211 | C | A | 0.0000 | Buried |
| 212 | N | A | -1.6291 | Soluble |
| 213 | V | A | 0.0000 | Buried |
| 214 | N | A | -2.0169 | Soluble |
| 215 | H | A | 0.0000 | Buried |
| 216 | K | A | -2.5600 | Soluble |
| 217 | P | A | -1.5763 | Soluble |
| 218 | S | A | -1.9155 | Soluble |
| 219 | N | A | -2.3982 | Soluble |
| 220 | T | A | -2.0769 | Soluble |
| 221 | K | A | -2.7157 | Soluble |
| 222 | V | A | -1.7748 | Soluble |
| 223 | D | A | -2.4856 | Soluble |
| 224 | K | A | -2.3163 | Soluble |
| 225 | R | A | -2.7894 | Soluble |
| 226 | V | A | 0.0000 | Buried |
| 227 | E | A | -2.9072 | Soluble |
| 228 | P | A | -1.9569 | Soluble |
| 229 | K | A | -2.8735 | Soluble |
| 230 | S | A | -2.1657 | Soluble |
| 231 | C | A | -2.5119 | Soluble |
| 232 | D | A | -3.3459 | Soluble |
| 233 | K | A | -3.3878 | Soluble |
| 234 | T | A | -2.7511 | Soluble |
| 235 | H | A | -2.4383 | Soluble |
| 1 | D | B | -2.3495 | Soluble |
| 2 | I | B | 0.0000 | Buried |
| 3 | Q | B | -2.1906 | Soluble |
| 4 | M | B | 0.0000 | Buried |
| 5 | T | B | -0.9428 | Soluble |
| 6 | Q | B | 0.0000 | Buried |
| 7 | S | B | -0.5900 | Soluble |
| 8 | P | B | -0.5927 | Soluble |
| 9 | S | B | -0.8101 | Soluble |
| 10 | S | B | -0.8345 | Soluble |
| 11 | L | B | -0.4855 | Soluble |
| 12 | S | B | -0.6924 | Soluble |
| 13 | A | B | -0.9443 | Soluble |
| 14 | S | B | -0.8960 | Soluble |
| 15 | V | B | -0.2637 | Soluble |
| 16 | G | B | -1.0167 | Soluble |
| 17 | D | B | -2.0449 | Soluble |
| 18 | R | B | -2.4212 | Soluble |
| 19 | V | B | 0.0000 | Buried |
| 20 | T | B | -0.7513 | Soluble |
| 21 | I | B | 0.0000 | Buried |
| 22 | T | B | -0.6731 | Soluble |
| 23 | C | B | 0.0000 | Buried |
| 24 | R | B | -2.2027 | Soluble |
| 25 | S | B | 0.0000 | Buried |
| 26 | S | B | -2.2813 | Soluble |
| 27 | Q | B | -2.7514 | Soluble |
| 28 | R | B | -2.5355 | Soluble |
| 29 | I | B | 0.0000 | Buried |
| 36 | M | B | -0.1904 | Soluble |
| 37 | T | B | 0.0169 | Aggregation-prone |
| 38 | Y | B | 0.8867 | Aggregation-prone |
| 39 | L | B | 0.0000 | Buried |
| 40 | N | B | 0.0000 | Buried |
| 41 | W | B | 0.0000 | Buried |
| 42 | Y | B | 0.0000 | Buried |
| 43 | Q | B | 0.0000 | Buried |
| 44 | Q | B | 0.0000 | Buried |
| 45 | K | B | -1.5522 | Soluble |
| 46 | P | B | -1.4941 | Soluble |
| 47 | G | B | -1.7581 | Soluble |
| 48 | K | B | -2.3721 | Soluble |
| 49 | A | B | -1.5105 | Soluble |
| 50 | P | B | 0.0000 | Buried |
| 51 | K | B | -1.2621 | Soluble |
| 52 | L | B | 0.0000 | Buried |
| 53 | L | B | 0.0000 | Buried |
| 54 | I | B | 0.0000 | Buried |
| 55 | F | B | 0.3272 | Aggregation-prone |
| 56 | V | B | 0.6032 | Aggregation-prone |
| 57 | A | B | 0.0000 | Buried |
| 65 | S | B | -0.7887 | Soluble |
| 66 | H | B | -1.0714 | Soluble |
| 67 | S | B | -0.9629 | Soluble |
| 68 | Q | B | -0.8768 | Soluble |
| 69 | S | B | -0.7337 | Soluble |
| 70 | G | B | -0.5944 | Soluble |
| 71 | V | B | -0.4132 | Soluble |
| 72 | P | B | -0.5392 | Soluble |
| 74 | S | B | -0.7565 | Soluble |
| 75 | R | B | -1.0661 | Soluble |
| 76 | F | B | 0.0000 | Buried |
| 77 | R | B | -1.5262 | Soluble |
| 78 | G | B | 0.0000 | Buried |
| 79 | S | B | -0.9146 | Soluble |
| 80 | G | B | -0.9268 | Soluble |
| 83 | S | B | -1.0431 | Soluble |
| 84 | E | B | -1.7280 | Soluble |
| 85 | T | B | -2.1240 | Soluble |
| 86 | D | B | -2.1698 | Soluble |
| 87 | F | B | 0.0000 | Buried |
| 88 | T | B | -0.7963 | Soluble |
| 89 | L | B | 0.0000 | Buried |
| 90 | T | B | -0.9447 | Soluble |
| 91 | I | B | 0.0000 | Buried |
| 92 | S | B | -1.4831 | Soluble |
| 93 | G | B | -1.2448 | Soluble |
| 94 | L | B | 0.0000 | Buried |
| 95 | Q | B | -0.9508 | Soluble |
| 96 | P | B | -1.5152 | Soluble |
| 97 | E | B | -1.8707 | Soluble |
| 98 | D | B | 0.0000 | Buried |
| 99 | S | B | 0.0000 | Buried |
| 100 | A | B | 0.0000 | Buried |
| 101 | T | B | -0.7552 | Soluble |
| 102 | Y | B | 0.0000 | Buried |
| 103 | Y | B | 0.0000 | Buried |
| 104 | C | B | 0.0000 | Buried |
| 105 | Q | B | 0.0000 | Buried |
| 106 | Q | B | 0.0000 | Buried |
| 107 | S | B | 0.0000 | Buried |
| 108 | F | B | 1.2640 | Aggregation-prone |
| 109 | W | B | 0.8677 | Aggregation-prone |
| 114 | T | B | 0.4473 | Aggregation-prone |
| 115 | P | B | -0.1712 | Soluble |
| 116 | L | B | 0.0912 | Aggregation-prone |
| 117 | T | B | -0.5423 | Soluble |
| 118 | F | B | 0.0000 | Buried |
| 119 | G | B | 0.0000 | Buried |
| 120 | G | B | -1.2183 | Soluble |
| 121 | G | B | -0.9472 | Soluble |
| 122 | T | B | 0.0000 | Buried |
| 123 | K | B | -1.4848 | Soluble |
| 124 | V | B | 0.0000 | Buried |
| 125 | E | B | -1.1061 | Soluble |
| 126 | I | B | 0.0000 | Buried |
| 127 | K | B | -1.0693 | Soluble |
| 128 | R | B | -0.6967 | Soluble |
| 129 | T | B | -0.0616 | Soluble |
| 130 | V | B | 0.3496 | Aggregation-prone |
| 131 | A | B | -0.0238 | Soluble |
| 132 | A | B | -0.0753 | Soluble |
| 133 | P | B | 0.0000 | Buried |
| 134 | S | B | -0.2061 | Soluble |
| 135 | V | B | 0.0000 | Buried |
| 136 | F | B | 0.0092 | Aggregation-prone |
| 137 | I | B | 0.0142 | Aggregation-prone |
| 138 | F | B | 0.0000 | Buried |
| 139 | P | B | -0.4990 | Soluble |
| 140 | P | B | -0.7705 | Soluble |
| 141 | S | B | -1.3703 | Soluble |
| 142 | D | B | -2.6991 | Soluble |
| 143 | E | B | -2.3290 | Soluble |
| 144 | Q | B | 0.0000 | Buried |
| 145 | L | B | -1.9619 | Soluble |
| 146 | K | B | -2.5221 | Soluble |
| 147 | S | B | -1.5990 | Soluble |
| 148 | G | B | -1.2283 | Soluble |
| 149 | T | B | -0.9125 | Soluble |
| 150 | A | B | 0.0000 | Buried |
| 151 | S | B | 0.0000 | Buried |
| 152 | V | B | 0.0000 | Buried |
| 153 | V | B | 0.0000 | Buried |
| 154 | C | B | 0.0000 | Buried |
| 155 | L | B | 0.0000 | Buried |
| 156 | L | B | 0.0000 | Buried |
| 157 | N | B | 0.0000 | Buried |
| 158 | N | B | -0.8104 | Soluble |
| 159 | F | B | 0.0000 | Buried |
| 160 | Y | B | 0.0000 | Buried |
| 161 | P | B | -1.5038 | Soluble |
| 162 | R | B | -2.6129 | Soluble |
| 163 | E | B | -2.9550 | Soluble |
| 164 | A | B | -2.1811 | Soluble |
| 165 | K | B | -2.4256 | Soluble |
| 166 | V | B | -1.0304 | Soluble |
| 167 | Q | B | -0.6233 | Soluble |
| 168 | W | B | 0.0000 | Buried |
| 169 | K | B | -0.6185 | Soluble |
| 170 | V | B | 0.0000 | Buried |
| 171 | D | B | -1.9272 | Soluble |
| 172 | N | B | -1.5288 | Soluble |
| 173 | A | B | -0.2484 | Soluble |
| 174 | L | B | 0.7652 | Aggregation-prone |
| 175 | Q | B | -0.0488 | Soluble |
| 176 | S | B | -0.4229 | Soluble |
| 177 | G | B | -0.8111 | Soluble |
| 178 | N | B | -0.6725 | Soluble |
| 179 | S | B | -0.8093 | Soluble |
| 180 | Q | B | -0.7842 | Soluble |
| 181 | E | B | -1.4102 | Soluble |
| 182 | S | B | -0.6176 | Soluble |
| 183 | V | B | -0.7008 | Soluble |
| 184 | T | B | -1.0630 | Soluble |
| 185 | E | B | -2.2236 | Soluble |
| 186 | Q | B | -1.9657 | Soluble |
| 187 | D | B | -1.9971 | Soluble |
| 188 | S | B | -2.1343 | Soluble |
| 189 | K | B | -2.4942 | Soluble |
| 190 | D | B | -1.7319 | Soluble |
| 191 | S | B | 0.0000 | Buried |
| 192 | T | B | 0.0000 | Buried |
| 193 | Y | B | 0.0000 | Buried |
| 194 | S | B | 0.0000 | Buried |
| 195 | L | B | 0.0000 | Buried |
| 196 | S | B | 0.0000 | Buried |
| 197 | S | B | 0.0000 | Buried |
| 198 | T | B | -0.3798 | Soluble |
| 199 | L | B | 0.0000 | Buried |
| 200 | T | B | -0.2480 | Soluble |
| 201 | L | B | -0.7205 | Soluble |
| 202 | S | B | -1.2263 | Soluble |
| 203 | K | B | -2.3293 | Soluble |
| 204 | A | B | -2.1201 | Soluble |
| 205 | D | B | -2.7909 | Soluble |
| 206 | Y | B | 0.0000 | Buried |
| 207 | E | B | -3.8383 | Soluble |
| 208 | K | B | -3.7905 | Soluble |
| 209 | H | B | -3.0670 | Soluble |
| 210 | K | B | -3.2907 | Soluble |
| 211 | V | B | -1.7502 | Soluble |
| 212 | Y | B | 0.0000 | Buried |
| 213 | A | B | 0.0000 | Buried |
| 214 | C | B | 0.0000 | Buried |
| 215 | E | B | -0.7904 | Soluble |
| 216 | V | B | 0.0000 | Buried |
| 217 | T | B | -1.0623 | Soluble |
| 218 | H | B | 0.0000 | Buried |
| 219 | Q | B | -1.6882 | Soluble |
| 220 | G | B | -0.4501 | Soluble |
| 221 | L | B | -0.2255 | Soluble |
| 222 | S | B | -0.4456 | Soluble |
| 223 | S | B | -0.4039 | Soluble |
| 224 | P | B | -0.5248 | Soluble |
| 225 | V | B | 0.0204 | Aggregation-prone |
| 226 | T | B | -0.4527 | Soluble |
| 227 | K | B | -0.7506 | Soluble |
| 228 | S | B | -0.6981 | Soluble |
| 229 | F | B | 0.0000 | Buried |
| 230 | N | B | -1.9741 | Soluble |
| 231 | R | B | -2.9400 | Soluble |
| 232 | G | B | -2.7530 | Soluble |
| 233 | E | B | -3.1161 | Soluble |
| 234 | C | B | -2.0828 | Soluble |
3D Structure — colored by A4D score
pH-Dependent Aggregation Profiles
A4D scores calculated across 11 pH conditions (4.0–9.0, step 0.5). Click a row to view the structure at that pH. The input structure is globular — max score is recommended for pH analysis.
| pH | Avg A4D Score | Max A4D Score | Downloads |
|---|---|---|---|
| 4.0 | -0.786 | 3.9971 | CSV PDB |
| 4.5 | -0.8295 | 3.9971 | CSV PDB |
| 5.0 | -0.8805 | 3.9971 | CSV PDB |
| 5.5 | -0.928 | 3.9971 | CSV PDB |
| 6.0 | -0.9602 | 3.9971 | CSV PDB |
| 6.5 | -0.9684 | 3.9971 | CSV PDB |
| 7.0 | -0.9537 | 3.9971 | CSV PDB |
| 7.5 | -0.9247 | 3.997 | CSV PDB |
| 8.0 | -0.8881 | 3.997 | CSV PDB |
| 8.5 | -0.8459 | 3.9968 | CSV PDB |
| 9.0 | -0.7976 | 3.9961 | CSV PDB |