Global Registry
A4D-Ab
Abelacimab
A4DAB003
|
Cardiovascular / hemostasis disorders
|
Phase-III
Target
F11
Isotype / Subclass
G1 / IgG1
Company
Novartis
Anthos Therapeutics
Labcorp Drug Development
TIMI Study Group
Clinical Status
Phase-III
Format
Whole mAb
Synonyms
MAA-868
pH Formulation
—
IMGT
PubChem (381128283)
PubChem (442064645)
PubChem (472419757)
PubChem (476262747)
PubChem (476269359)
PubChem (479821208)
PubChem (505547120)
PubChem (505923885)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6113
Score Range
-0.61
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB003_6r8x_C_B
6r8x
100%
-0.6113
6.0
9.0
-0.0712
-0.6872