Afasevikumab

A4DAB008 | Phase-I
IL17A
G1 / None
NovImmune Genentech
Phase-I
Whole mAb
MCAF-5352A MCAF5352A NI-1401 NI1401 RG-7624 RG7624 RO5553110
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IMGT PubChem (160671724) PubChem (381127661) PubChem (404772248) PubChem (472408711) PubChem (476262755) PubChem (476269367) Thera-SAbDab YAbS
Avg A4D Score
-0.6878
Score Range
-0.7 to -0.68
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB008_6ppg_H_L 6ppg 100% -0.6785 6.5 4.0 -0.3134 -0.7261
A4DAB008_6ppg_B_A 6ppg 100% -0.6971 6.5 4.0 -0.3499 -0.7432