Amivantamab

A4DAB012 | Cancer | Approved
EGFR/ERBB1/HER1;MET/HGFR
G1;G1 / IgG1
Genmab Janssen Research & Development
Approved
Bispecific mAb
CNTO4424 JNJ 372 JNJ372 JNJ-372 JNJ-61186372 JNJ61176372 JNJ-6372 JNJ6372 RYBREVANT
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IMGT PubChem (387065587) PubChem (402425829) PubChem (404719883) PubChem (472419032) PubChem (476262939) PubChem (476269205) PubChem (483927838) PubChem (498146128) PubChem (508533721) Thera-SAbDab YAbS
Avg A4D Score
-0.7063
Score Range
-0.71
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB012_6wvz_H_L 6wvz 100% -0.7063 6.5 4.0 -0.2545 -0.7607