Global Registry
A4D-Ab
Amlenetug
A4DAB013
|
Neurological disorders
|
Phase-III
Target
SNCA/PARK1/PARK4
Isotype / Subclass
G1 / IgG1
Company
Lundbeck
Clinical Status
Phase-III
Format
Whole mAb
Synonyms
LU AF82422
pH Formulation
—
IMGT
PubChem (440234775)
PubChem (472420424)
Thera-SAbDab
YAbS
Avg A4D Score
-0.7803
Score Range
-0.78
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB013_8b9v_H_L
8b9v
100%
-0.7803
6.5
4.0
-0.6724
-0.7928