Bafisontamab

A4DAB031 | Phase-I/II
EGFR/ERBB1/HER1;MET/HGFR
G1;non-canonical / None
EpimAb Biotherapeutics
Phase-I/II
Bispecific Mixed mAb and Fab
EMB-01 EMB01
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IMGT PubChem (440234656) PubChem (443566315) PubChem (472420422) PubChem (476262784) PubChem (476269446) Thera-SAbDab YAbS
Avg A4D Score
-0.6884
Score Range
-0.71 to -0.67
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB031_5sx5_H_L 5sx5 100% -0.6716 6.5 4.0 -0.4548 -0.6983
A4DAB031_5sx5_J_K 5sx5 100% -0.674 6.5 4.0 -0.4715 -0.6989
A4DAB031_5sx4_J_I 5sx4 100% -0.6952 6.5 4.0 -0.409 -0.7306
A4DAB031_5sx4_H_L 5sx4 100% -0.7129 6.5 4.0 -0.4499 -0.745