Basiliximab

A4DAB035 | Immune-mediated / inflammatory disorders | Approved
IL2RA/CD25
G1 / IgG1
Cerimon Pharmaceuticals Novartis
Approved
Whole mAb
CHI 621 CHI621 CHI-621 Simulect
6.5
IMGT PubChem (46505169) PubChem (50067184) PubChem (103771251) PubChem (135321271) PubChem (178103461) PubChem (440790690) PubChem (472386308) PubChem (472437799) PubChem (472440172) PubChem (481101529) PubChem (498150491) PubChem (519819562) Thera-SAbDab YAbS
Avg A4D Score
-0.6438
Score Range
-0.67 to -0.62
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB035_3iu3_C_D 3iu3 99% -0.6231 6.5 9.0 -0.3124 -0.6564
A4DAB035_3iu3_A_B 3iu3 99% -0.6313 6.5 9.0 -0.3227 -0.6644
A4DAB035_3iu3_H_L 3iu3 99% -0.646 6.5 9.0 -0.304 -0.6827
A4DAB035_1mim_H_L 1mim 99% -0.6748 6.5 9.0 -0.3798 -0.7062