Global Registry
A4D-Ab
Boserolimab
A4DAB053
|
Phase-II
Target
TNFRSF7/CD27
Isotype / Subclass
G1 / None
Company
Bionovion
Merck Sharp & Dohme
Clinical Status
Phase-II
Format
Whole mAb
Synonyms
MK-5890
MK5890
pH Formulation
—
IMGT
PubChem (471299212)
PubChem (472419510)
PubChem (476000903)
PubChem (485483263)
PubChem (485511845)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6878
Score Range
-0.69
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB053_8ds5_C_B
8ds5
100%
-0.6878
6.5
9.0
-0.5467
-0.7033