Certolizumab

A4DAB062 | Approved
TNF/TNFA
G1 / None
UCB
Approved
Fab
CDP-870 CDP870 Cimzia PHA-738144 PHA738144 Simziya
5.2
IMGT PubChem (135347437) PubChem (404719925) PubChem (472399115) PubChem (481155459) PubChem (505570956) Thera-SAbDab YAbS
Avg A4D Score
-0.6437
Score Range
-0.66 to -0.61
Structures
4
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB062_5wux_C_D 5wux 100% -0.6064 6.5 4.0 -0.1213 -0.6673
A4DAB062_5wuv_H_L 5wuv 100% -0.6567 6.5 9.0 0.0057 -0.7335
A4DAB062_5wux_H_L 5wux 100% -0.6496 6.5 4.0 -0.107 -0.7139
A4DAB062_5wux_A_B 5wux 100% -0.6622 6.5 9.0 -0.1141 -0.7276