Cobolimab

A4DAB068 | Cancer | Phase-III
HAVCR2/TIM3
G4 / IgG4
AnaptysBio GlaxoSmithKline TESARO
Phase-III
Whole mAb
GSK-4069889 GSK4069889 TSR 022 TSR-022 TSR022 WBP 296A WBP-296A WBP296A
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IMGT PubChem (381128219) PubChem (404719772) PubChem (472419575) PubChem (480403231) PubChem (481988094) PubChem (505573975) PubChem (513904321) PubChem (517704467) Thera-SAbDab YAbS
Avg A4D Score
-0.708
Score Range
-0.71
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB068_8gsi_B_A 8gsi 100% -0.708 6.5 9.0 -0.5849 -0.7207