Global Registry
A4D-Ab
Coltuximab
A4DAB069
|
Phase-II
Target
CD19
Isotype / Subclass
G1 / None
Company
ImmunoGen
Clinical Status
Phase-II
Format
Whole mAb ADC
Synonyms
SAR3419
SAR-3419
pH Formulation
—
IMGT
Thera-SAbDab
YAbS
Avg A4D Score
-0.6826
Score Range
-0.7 to -0.66
Structures
2
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB069_6ani_H_L
6ani
100%
-0.7036
6.5
4.0
-0.3948
-0.7391
A4DAB069_6ani_I_M
6ani
100%
-0.6617
6.5
4.0
-0.3228
-0.7011