Global Registry
A4D-Ab
Cugrastomig
A4DAB077
|
Phase-I/II
Target
LAG3/CD223;PDCD1/CD279/PD1
Isotype / Subclass
G1;non-canonical / None
Company
Akeso Biopharma
Kangfang Huike (Shanghai) Biology Co
Clinical Status
Phase-I/II
Format
Bispecific Mixed mAb and scFv
Synonyms
AK 129
AK-129
AK129
pH Formulation
—
IMGT
PubChem (496143715)
PubChem (520378124)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6896
Score Range
-0.69 to -0.69
Structures
2
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
Export CSV
Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB077_7um3_H_L
7um3
97%
-0.691
6.5
4.0
-0.3085
-0.7361
A4DAB077_7um3_I_M
7um3
97%
-0.6883
6.5
4.0
-0.3144
-0.7323