Dostarlimab

A4DAB090 | Cancer | Approved
PDCD1/CD279/PD1
G4 / IgG4
AnaptysBio European Network of Gynaecological Oncological Trial Groups GlaxoSmithKline TESARO
Approved
Whole mAb
ANB 011 ANB011 ANB-011 GSK-4057190 GSK4057190 JEMPERLI TSR 042 TSR042 TSR-042 WBP 285 WBP285 WBP-285
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IMGT PubChem (381128218) PubChem (404720301) PubChem (441604890) PubChem (472407780) PubChem (476262679) PubChem (476269281) PubChem (483928936) PubChem (498148676) PubChem (500131949) PubChem (505188562) Thera-SAbDab YAbS
Avg A4D Score
-0.6285
Score Range
-0.63
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB090_7wsl_H_L 7wsl 100% -0.6285 6.5 4.0 -0.1823 -0.6792