Efalizumab

A4DAB098 | Approved
ITGAL/CD11A/LFA1A
G1 / None
Genentech Merck Serono XOMA
Approved
Whole mAb
HU 1124 HU1124 HU-1124 Raptiva Xanelim
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IMGT PubChem (46505252) PubChem (50069676) PubChem (103771313) PubChem (135272703) PubChem (178103206) PubChem (329976983) PubChem (472399419) PubChem (472439124) PubChem (472441179) PubChem (480406065) PubChem (481101608) PubChem (488204503) PubChem (498146495) Thera-SAbDab YAbS
Avg A4D Score
-0.7356
Score Range
-0.75 to -0.72
Structures
5
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB098_3eoa_H_L 3eoa 100% -0.7434 6.5 9.0 -0.5065 -0.7733
A4DAB098_3eob_B_A 3eob 100% -0.7179 6.5 4.0 -0.4599 -0.7504
A4DAB098_3eo9_H_L 3eo9 100% -0.7274 6.5 9.0 -0.5527 -0.7495
A4DAB098_3eob_H_L 3eob 100% -0.7395 6.5 9.0 -0.5669 -0.7612
A4DAB098_3eoa_B_A 3eoa 100% -0.7497 6.5 9.0 -0.5215 -0.7784