Ginisortamab

A4DAB130 | Phase-I/II

Target GREM1

Isotype / Subclass G4 / None

Company

UCB

Clinical Status Phase-I/II

Format Whole mAb

Synonyms

UCB6114 UCB-6114

pH Formulation —

IMGT PubChem (442064868) PubChem (443566107) PubChem (458923804) PubChem (472422648) PubChem (476264150) PubChem (476270760) PubChem (498142835) Thera-SAbDab YAbS

Avg A4D Score

-0.7251

Score Range

-0.73

Structures

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB130_8b7h_H_L	8b7h	100%	-0.7251	7.0	4.0	N/A	N/A

Ginisortamab

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2