Global Registry
A4D-Ab
Isecarosmab
A4DAB155
|
Phase-I
Target
ADAMTSL5;ALB
Isotype / Subclass
non-canonical / None
Company
Merck
Clinical Status
Phase-I
Format
Whole mAb
Synonyms
M-6495
M 6495
M6495
pH Formulation
—
IMGT
PubChem (405023088)
PubChem (472422143)
PubChem (480403110)
PubChem (481987965)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6027
Score Range
-0.6
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
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Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB155_7quh_H_L
7quh
99%
-0.6027
6.5
4.0
0.0883
-0.6859