Melredableukin

A4DAB168 | Phase-II
Non-Binding
G1 / None
Roche
Phase-II
Whole mAb Fusion
RG-7835 RG7835 RG 7835 RO-7049665 RO7049665 RO 7049665
—
IMGT Thera-SAbDab YAbS
Avg A4D Score
-0.7106
Score Range
-0.73 to -0.7
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB168_6ghg_H_L 6ghg 100% -0.7021 6.5 4.0 -0.262 -0.7516
A4DAB168_6ghg_A_B 6ghg 100% -0.7252 6.5 4.0 -0.2452 -0.7784
A4DAB168_5i1c_H_L 5i1c 96% -0.7044 6.5 4.0 -0.1408 -0.7736