Global Registry
A4D-Ab
Muromonab
A4DAB173
|
Approved (withdrawn)
Target
CD3E
Isotype / Subclass
G2a / None
Company
Cancer Research UK
Ortho-McNeil
XOMA
Clinical Status
Approved (withdrawn)
Format
Whole mAb
Synonyms
Zolimomab
pH Formulation
—
IMGT
PubChem (46507837)
PubChem (103771420)
PubChem (472422762)
PubChem (472435494)
PubChem (472439862)
PubChem (481155587)
PubChem (498153009)
PubChem (504687574)
Thera-SAbDab
YAbS
Avg A4D Score
-0.7568
Score Range
-0.76
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB173_1sy6_H_L
1sy6
100%
-0.7568
6.5
4.0
-0.6718
-0.7667