Odesivimab

A4DAB187 | Approved
Zaire Ebolavirus Glycoprotein
G1 / None
Regeneron Pharmaceuticals
Approved
Whole mAb
REGN 3471 REGN3471 REGN-3471 INMAZEB (combination with Atoltivimab and Maftivimab)
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IMGT PubChem (381608746) PubChem (404719778) PubChem (472407781) PubChem (480403181) PubChem (481988044) PubChem (505852078) PubChem (508534651) PubChem (513907260) Thera-SAbDab YAbS
Avg A4D Score
-0.5092
Score Range
-0.54 to -0.48
Structures
3
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB187_7tn9_M_N 7tn9 73% -0.4843 6.5 4.0 -0.0429 -0.596
A4DAB187_7tn9_O_P 7tn9 73% -0.5058 6.5 4.0 -0.0952 -0.6108
A4DAB187_7tn9_Q_R 7tn9 73% -0.5375 6.5 4.0 -0.1491 -0.634