Global Registry
A4D-Ab
Omburtamab
A4DAB192
|
Cancer
|
Preregistration
Target
B7H3/CD276
Isotype / Subclass
G1 / IgG1
Company
Memorial Sloan-Kettering Cancer Center
Y-mAbs Therapeutics
Clinical Status
Preregistration
Format
Whole mAb Radiolabelled
Synonyms
OMBLASTYS
pH Formulation
—
IMGT
PubChem (381128149)
PubChem (404719716)
PubChem (472420141)
PubChem (472435498)
PubChem (472439868)
PubChem (481155541)
PubChem (498149659)
PubChem (505852690)
Thera-SAbDab
YAbS
Avg A4D Score
-0.7735
Score Range
-0.77
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
Export CSV
Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB192_5cma_B_A
5cma
100%
-0.7735
6.5
4.0
-0.4642
-0.81