Orilanolimab

A4DAB196 | Phase-II
FCGRT/FcRn
G4 / None
Syntimmune
Phase-II
Whole mAb
ALXN 1830 ALXN1830 ALXN-1830 SYNT-001 SYNT001 SYNT 001 SYNT-1 SYNT1 SYNT 1 SYNT1001 SYNT-1001 SYNT 1001
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IMGT PubChem (381128248) PubChem (404720518) PubChem (404772743) PubChem (472419735) PubChem (480403204) PubChem (481988067) PubChem (498148259) Thera-SAbDab YAbS
Avg A4D Score
-0.7297
Score Range
-0.73
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB196_6nha_H_L 6nha 100% -0.7297 6.5 9.0 -0.4434 -0.7638