Osocimab

A4DAB197 | Phase-II

Target F11

Isotype / Subclass G1 / None

Company

Bayer HealthCare

Clinical Status Phase-II

Format Whole mAb

Synonyms

BAY-121379 BAY121379 BAY 121379

pH Formulation —

IMGT PubChem (381128246) PubChem (404720319) PubChem (404772268) PubChem (440816735) PubChem (472420951) PubChem (480403207) PubChem (481988070) Thera-SAbDab YAbS

Avg A4D Score

-0.7098

Score Range

-0.71

Structures

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB197_6hhc_H_L	6hhc	99%	-0.7098	6.5	4.0	-0.3014	-0.7604

Osocimab

Avg. A4D Score per Structure

pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2