Palverafusp

A4DAB200 | Phase-I/II
VEGF
G1 / None
ImmuneOnco Biopharma
Phase-I/II
Fusion Protein
IMM-2510 IMM2510 IMM 2510
—
Avg A4D Score
-0.6556
Score Range
-0.68 to -0.62
Structures
6
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB200_5x8l_G_L 5x8l 100% -0.669 6.5 4.0 -0.2149 -0.7246
A4DAB200_5x8l_J_O 5x8l 100% -0.6449 7.0 4.0 -0.2084 -0.6971
A4DAB200_5xxy_H_L 5xxy 99% -0.6532 6.5 4.0 -0.1812 -0.71
A4DAB200_5x8l_S_N 5x8l 100% -0.6674 6.5 4.0 -0.2012 -0.7241
A4DAB200_5x8l_F_K 5x8l 100% -0.6838 6.5 4.0 -0.2015 -0.7409
A4DAB200_5x8l_H_M 5x8l 100% -0.6156 6.5 4.0 -0.1601 -0.6695