Romlusevimab

A4DAB227 | Phase-II/III
SARS-CoV-2 Spike RBD
G1 / None
Brii Biosciences
Phase-II/III
Whole mAb
BRII-198 BRII198 BRII 198
—
IMGT PubChem (442064693) PubChem (443565775) PubChem (472423206) PubChem (480403245) PubChem (481988108) PubChem (513907303) Thera-SAbDab YAbS
Avg A4D Score
-0.6074
Score Range
-0.63 to -0.58
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB227_8gx9_P_M 8gx9 99% -0.6312 6.5 9.0 -0.2021 -0.6856
A4DAB227_8gx9_O_N 8gx9 99% -0.5835 6.5 9.0 -0.1868 -0.6341