Porustobart

A4DAB230 | Phase-II
CTLA4/CD152
G1 / None
Harbour Biomed
Phase-II
Whole mAb Fusion
HBM-4003 HBM4033 HBM 4033 HCAb-4003-2
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IMGT PubChem (471298931) PubChem (474492459) PubChem (476000927) Thera-SAbDab YAbS
Avg A4D Score
-0.7146
Score Range
-0.73 to -0.7
Structures
2
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB230_6x4t_B_E 6x4t 100% -0.7255 6.5 9.0 -0.372 -0.7691
A4DAB230_6x4t_D_F 6x4t 100% -0.7036 6.5 4.0 -0.1875 -0.7676