Serplulimab

A4DAB238 | Cancer | Approved
PDCD1/CD279/PD1
G4 / IgG4
Henlix Biotech Shanghai Henlius Biotech
Approved
Whole mAb
HLX-10 HLX10 HLX 10
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IMGT PubChem (402426057) PubChem (440234555) PubChem (472419871) PubChem (473142883) PubChem (473143251) PubChem (498145082) PubChem (505880864) PubChem (507750429) PubChem (513906310) Thera-SAbDab YAbS
Avg A4D Score
-0.6768
Score Range
-0.68
Structures
1
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity

Associated Structural Profiles Level 2

Structure ID Source PDB Seq. Identity Avg. A4D Score pH (Min Agg.) pH (Max Agg.) Score CDR Score non-CDR
A4DAB238_7e9b_H_L 7e9b 100% -0.6768 6.5 4.0 -0.149 -0.737