Global Registry
A4D-Ab
Trabikibart
A4DAB275
|
Phase-I
Target
CSF2RB/CD131/IL3RB/IL5RB
Isotype / Subclass
G4 / None
Company
CSL
Clinical Status
Phase-I
Format
Whole mAb
Synonyms
CSL311
CSL-311
pH Formulation
—
IMGT
PubChem (478839002)
PubChem (485483414)
PubChem (485511916)
PubChem (494430853)
Thera-SAbDab
YAbS
Avg A4D Score
-0.7233
Score Range
-0.72
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB275_5dwu_H_L
5dwu
100%
-0.7233
6.0
9.0
-0.2339
-0.7828