Global Registry
A4D-Ab
Tusamitamab
A4DAB280
|
Phase-III
Target
CEACAM5/CD66e
Isotype / Subclass
G1 / None
Company
Sanofi-Aventis
Clinical Status
Phase-III
Format
Whole mAb
Synonyms
IBI-126
IBI126
IBI 126
SAR 701
SAR701
SAR-701
SAR-408701
SAR 408701
SAR408701
pH Formulation
—
IMGT
PubChem (433770569)
PubChem (472422421)
PubChem (476001011)
PubChem (481155577)
PubChem (498143571)
PubChem (505057006)
Thera-SAbDab
YAbS
Avg A4D Score
-0.4896
Score Range
-0.49
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
Export CSV
Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB280_8bw0_H_L
8bw0
100%
-0.4896
7.0
4.0
0.1209
-0.6546