Umesolerbart

A4DAB281 | Phase-III

Target Bet v 1

Isotype / Subclass G4 / None

Company

Regeneron

Clinical Status Phase-III

Format Whole mAb

Synonyms

REGN5713-5714-5715 (combination of Atisnolerbart Bremzalerbart and Umesolerbart)

pH Formulation —

IMGT PubChem (471299149) PubChem (474492746) PubChem (476000826) PubChem (485483314) PubChem (485511887) Thera-SAbDab YAbS

Avg A4D Score

-0.6563

Score Range

-0.66

Structures

1

Structure ID	Source PDB	Seq. Identity	Avg. A4D Score	pH (Min Agg.)	pH (Max Agg.)	Score CDR	Score non-CDR
A4DAB281_7mxl_H_L	7mxl	100%	-0.6563	6.5	4.0	-0.3351	-0.6948