Global Registry
A4D-Ab
Vesencumab
A4DAB292
|
Phase-I
Target
NRP1
Isotype / Subclass
G1 / None
Company
Genentech
Roche
Clinical Status
Phase-I
Format
Whole mAb
Synonyms
M 1685A
M1685A
M-1685A
MNRP 1685A
MNRP-1685A
MNRP1685A
R 7347
R7347
R-7347
RG7347
RG-7347
RG 7347
pH Formulation
—
IMGT
PubChem (160666633)
PubChem (381126585)
PubChem (404772855)
PubChem (472387951)
PubChem (476262719)
PubChem (476269328)
PubChem (497983080)
PubChem (505897752)
PubChem (513906596)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6685
Score Range
-0.67
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB292_2qqn_H_L
2qqn
100%
-0.6685
6.5
4.0
-0.0364
-0.7496