Global Registry
A4D-Ab
Vopikitug
A4DAB301
|
Phase-I
Target
IL2RA/CD25
Isotype / Subclass
G1 / None
Company
Roche
Clinical Status
Phase-I
Format
Whole mAb
Synonyms
RG 6292
RG-6292
RG6962
RO 7296682
RO-7296682
RO7296682
pH Formulation
—
IMGT
PubChem (442064859)
PubChem (472423545)
PubChem (485483339)
PubChem (485511908)
Thera-SAbDab
YAbS
Avg A4D Score
-0.6414
Score Range
-0.64
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB301_6yio_H_L
6yio
100%
-0.6414
6.5
9.0
0.1194
-0.7395