Global Registry
A4D-Ab
Xaluritamig
A4DAB303
|
Cancer
|
Phase-III
Target
STEAP1;CD3
Isotype / Subclass
G1;non-canonical / TBD
Company
Amgen
Xencor
BeiGene
Clinical Status
Phase-III
Format
Bispecific Mixed mAb and scFv
Synonyms
AMG-509
AMG509
AMG 509
pH Formulation
—
IMGT
PubChem (471299029)
PubChem (474492365)
PubChem (507750352)
Thera-SAbDab
YAbS
Avg A4D Score
-0.5728
Score Range
-0.57
Structures
1
Show Structure Profiles
Avg. A4D Score per Structure
pH at Min / Max Aggregation Propensity
Associated Structural Profiles
Level 2
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Column Filters
Min Seq. Identity (%)
0
Min Avg A4D Score
-5.0
Max Avg A4D Score
2.0
Min pH (min agg. prop.)
0.0
Max pH (max agg. prop.)
14.0
Reset Filters
Structure ID
Source PDB
Seq. Identity
Avg. A4D Score
pH (Min Agg.)
pH (Max Agg.)
Score CDR
Score non-CDR
A4DAB303_8ucd_H_L
8ucd
100%
-0.5728
7.0
4.0
-0.0591
-0.7085